![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by edgaras on April 29, 2006, at 0:10:19
I have tried using ferulic acid for athletic performance enhancing properties, however,
I have noticed significant cognitive effects.
I wanted to know if anyone had similar experience.I have used ziprasidone [Geodon] [<10 mg] for over a year to limit psychotic effects of amphetamines [Adderall]. However, I do not like it, as it causes weight gain, and makes me restless and depressed. However, without the use of ziprasidone [Geodon] I would become very unorganized and would be lost in a state that I would to refer to as delerium.
I first tried ferulic acid few months ago, and noticed that my thoughts are much more stable and more orgnaized, and that I am not as confused. I was able to discontinue ziprasidone for 3 weeks.
After stopping to take ferulic acid, I was back to confused state of mind, and was forced to go back on ziprasidone.I have started taking ferulic acid again, 250 mg/day and I feel that I do not need to take ziprasidone to stabilize my mind anymore. It's been two weeks.
The effect of ferulic acid that
I get is similar to ziprasidone - if I am in a almost manic mood - very excited and happy, it tends to stabilize me.As far as side effects I have not experienced any,
except for minimal effect on mood, but the
effects appear to be not as drastic as those of
ziprasidone.
After I have check online, I was suprized to learn that ferulic acid might effect norepinephrine in the brain.Thus, my hypothesis -
ferulic acid might serve as alternative treatment method for some of the cognitive conditions.Here the references:
It appears that ferulic acid interacts with brain norepinephrine metabolism, possibly correcting deficiencies in norepinephrine(2). As a result, brain norepinephrine levels were normalized, with concomitant release of antistress hormones such as somatotrophin and endorphins(6).6)Ieiri, et. al., The Effects of Gamma Oryzanol on the Hypothalamo-Pituitary Axis, Folia Endocrinol., Japan, 58(1):1350/1982.
... increase the release of dopamine and norepinephrine, in the brain. [4]
[4] Wheeler KB, Garleb KA. Gamma oryzanol-plant sterol supplementation: metabolic, endocrine, and physiologic effects. Int J Sport Nutr. Jun1991;1(2):170-7.
http://content.nhiondemand.com/moh/media/monoVMN.asp?ctype=ds&mtyp=4&objID=100401
http://www.seabuckthorn.com/FerulicAcid.htm
Posted by Larry Hoover on May 24, 2006, at 12:21:37
In reply to ferulic acid - antipsychotic?, posted by edgaras on April 29, 2006, at 0:10:19
> I have tried using ferulic acid for athletic performance enhancing properties, however,
> I have noticed significant cognitive effects.
> I wanted to know if anyone had similar experience.I really don't know what to say, as the literature is full of confounds. Rice bran oil, the parent for the ferulic acid/gamma oryzanol, contains only small amounts of this mixture of substances. It's really a complex mixture of plant steroids, and their ferulic acid esters.
If it works, it works. Just watch for adverse effects. Plan occasional "holidays" from the substance, if you can manage that. Traditional use of this substance is never long-term, so there is no supporting evidence for using it that way.
Lar
This is the end of the thread.
Psycho-Babble Alternative | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.