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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by mike99 on March 23, 2006, at 12:48:38
I guess this could go on the alternative board, but since it's related to med interactions/mechanisms I thought it would getter better exposure here.
My question is regarding green tea's actions as an maoi (a/b?). Apparently it has some mao inhibitory actions.
Would one need to be cautious about taking high doses of green tea (ie 10-20 cups worth in liquid or other extract form) with meds or foods that are usually contraindicated with maoi's?
Thanks y'all.
Posted by linkadge on March 23, 2006, at 12:48:38
In reply to mao inhibition---green tea caution?, posted by mike99 on March 22, 2006, at 18:04:30
I did not know it was a MAO inhibitor. Do you have any literature on that ? I knew it was a COMT inhibitor, which affects the metabolism of norepinephrine and dopamine. I've heard of people combining COMT inhibitors with MAOI's, though I don't know the consensious.
Linkadge
Posted by mike99 on March 23, 2006, at 12:48:38
In reply to Re: mao inhibition---green tea caution?, posted by linkadge on March 23, 2006, at 9:18:40
Hey Linkadge,My mistake...thanks for clearing that up for me. I confused COMT for MAOI. I do not know it to be an MAOI.
Might you happen to know if there any general precautions for COMT's and other drugs such as opiods or stimulants?
I am also wondering if it would be safe to take large doses of green tea w/ provigil since both have dopamine reuptake inhibitory actions (?).
Or a TCA for that matter.
Thanks again.
Mike
Posted by linkadge on March 23, 2006, at 15:24:58
In reply to Re: mao inhibition---green tea caution? » linkadge, posted by mike99 on March 23, 2006, at 12:27:48
That is a very good question, and I would like to hear a good answer. From experience, norepinephrine reuptake interacted with COMT inhibition, but MAO inhibition did not seem to interact with COMT inhibition.
The flavanoid quercetin is a COMT/MAO inhibitor.
I was taking a TCA with green tea and definately noticed advere effects.
Linkadge
Posted by mike99 on March 24, 2006, at 18:57:53
In reply to Re: mao inhibition---green tea caution?, posted by linkadge on March 23, 2006, at 15:24:58
> That is a very good question, and I would like to hear a good answer.
Me too.
> The flavanoid quercetin is a COMT/MAO inhibitor.Interesting. Quercetin is found in apples and certain teas if I'm not mistaken.
>
> I was taking a TCA with green tea and definately noticed advere effects.I did too after taking a vicodin and green tea.
Posted by linkadge on March 25, 2006, at 11:52:02
In reply to Re: mao inhibition---green tea caution? » linkadge, posted by mike99 on March 24, 2006, at 18:57:53
Yeah, quercetin is in apples, garlic, and olive oil. It comes in greater quentities in supplements though.
Linkadge
This is the end of the thread.
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