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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by eloaf on May 7, 2005, at 19:07:25
Ive heard that St. Johns Wort is not suposed to be taken with certain medication and was wondering if it is safe to take it with trileptal?
Posted by Phillipa on May 7, 2005, at 19:07:25
In reply to trileptal, posted by eloaf on May 7, 2005, at 18:15:19
I know you're not supposed to take it with SSRI's . Fondly, Phillipa
Posted by Phillipa on May 7, 2005, at 19:20:51
In reply to trileptal, posted by eloaf on May 7, 2005, at 18:15:19
Want to stay on the Thread. Fondly, Phillipa
Posted by Larry Hoover on May 15, 2005, at 12:46:39
In reply to trileptal, posted by eloaf on May 7, 2005, at 18:15:19
> Ive heard that St. Johns Wort is not suposed to be taken with certain medication and was wondering if it is safe to take it with trileptal?
Not a good idea. They both affect enzyme 3A4, and both induce it (increase the activity). Carbamazepine is also a substrate at 3A4, so it self-induces its own elimination. If you combined the two, you might lose some carbamazepine effect, *and* change the blood concentration of other substances even more than the Trileptal did on its own.
Lar
This is the end of the thread.
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