![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 29 to 53 of 53. Go back in thread:
Posted by SLS on April 9, 2018, at 21:04:57
In reply to Re: Why is alcohol the only thing that helps me? » SLS, posted by Prefect on April 9, 2018, at 19:49:36
> I'm discontinuing zoloft because it's not not working. I've been on it for almost a year at 150mg per day and it's not helping. I've also read zoloft and lamictal are a toxic combination.
I didn't know that. In what way are they toxic?
> I want to taper of and either try prozac with lamital or luvox with abilify.
Will you add Lamictal if you go with Abilify and Luvox? I should think that the three drugs would go together well. What do you think?
- Scott
Posted by Prefect on April 9, 2018, at 21:16:47
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by SLS on April 9, 2018, at 21:04:57
Aparently one severly interferences with clearance of the other:
https://www.ncbi.nlm.nih.gov/pubmed/9627209
But I've read positive literature about prozac/lamictal combo for depersonizaltion disorder.
Why do you feel lamictal would be a good add on to luvox+abilify?
Posted by SLS on April 9, 2018, at 22:43:48
In reply to Re: Why is alcohol the only thing that helps me? » SLS, posted by Prefect on April 9, 2018, at 21:16:47
> Aparently one severly interferences with clearance of the other:
>
> https://www.ncbi.nlm.nih.gov/pubmed/9627209
>
> But I've read positive literature about prozac/lamictal combo for depersonizaltion disorder.
>
> Why do you feel lamictal would be a good add on to luvox+abilify?I have seen Abilify + Lamictal work well for a woman with severe depression. These drugs are also critical for my feeling better (not remission yet). In my opinion, both drugs are pro-dopaminergic, albeit via different mechanisms. Abilify often acts to make SSRIs work better, so perhaps the three drugs together will help you. Lamictal is metabolized by glucuronidation, not by CYP450 enzymes, so I don't see any problems with pharmacokinetics. You might want to start Abilify at 2.0-5.0 mg/day. It is metabolized by CYP450 3A4 and 2D6. Luvox might increase blood levels of Abilify. I'm not sure. For me, 15 mg/day of Abilify is optimal, but I have bipolar depression. I had severe depersonalization and derealization earlier in the course of my illness. If depersonalization is a feature of your condition, you might need to titrate the Abilify upwards. There are reports of Abilify helping:
https://www.ncbi.nlm.nih.gov/pubmed/24992087
Keep bothering Linkadge. He knows his stuff and thinks outside the box. I'm sure he can help you.
- Scott
Posted by Prefect on April 10, 2018, at 11:07:07
In reply to Re: Why is alcohol the only thing that helps me?, posted by SLS on April 9, 2018, at 22:43:48
I'll be taking Luvox at night. Would I take Lamictal at nigh too? I suspect it's somewhat sedating.
Posted by Prefect on April 10, 2018, at 11:18:47
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by bleauberry on April 9, 2018, at 13:14:20
BTW I should mention I've tested positive for Bartonella not even through a specialized testing lab but a public health lab.
You mention Ritalin, would low dose abilify not rebalance dopamine levels as well? It's a D1 agonist.
Posted by Prefect on April 10, 2018, at 12:21:03
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by bleauberry on April 9, 2018, at 13:14:20
Also I have a lot of inner tension, tachycardia, and sensory agitation. Would Ritalin not make this worse, because it's also a norepinephrine reuptake inhibitor. I went on Fetzima last year for a weak and it turned me into a basketcase.
Posted by linkadge on April 10, 2018, at 16:50:42
In reply to Re: Why is alcohol the only thing that helps me? » bleauberry, posted by Prefect on April 9, 2018, at 20:13:00
There are a few new studies linking overuse of antibiotics to an increased risk of future heart disease.
Of course, if you need them, use them. The notion, however, that people should be on a steady stream of antibioticis is perhaps a bit unwise.
Linkadge
Posted by SLS on April 10, 2018, at 17:08:00
In reply to Re: Why is alcohol the only thing that helps me? » bleauberry, posted by Prefect on April 10, 2018, at 12:21:03
> Also I have a lot of inner tension, tachycardia, and sensory agitation. Would Ritalin not make this worse, because it's also a norepinephrine reuptake inhibitor. I went on Fetzima last year for a weak and it turned me into a basketcase.
Fetzima sucks - except when it works :-). I just don't see any success stories, and I didn't like how milnacipran affects me.
Regarding Abilify, it is a D2/D3 partial agonist. It is thought to stabilize dopamine transmission. Abilify boosts transmission when there isn't enough (antidepressant) and dampens it when there is too much (antipsychotic). That's a bit simplistic, I guess.
Regarding Lamictal, you might find it a bit stimulating at first. Not like Ritalin, though. It is likely to be rather pleasant and feels like an antidepressant. This phenomenon can occur at 50 mg/day. If so, it will probaby fade in between dosage increases. For me, 200 mg/day helps quite a bit, but I need 300 mg/day to get the most improvement from Lamictal.
- Scott
Posted by Prefect on April 10, 2018, at 23:46:12
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by SLS on April 10, 2018, at 17:08:00
So my doctor refuses to give me more cloanzepam to ween off the alcohol. She presecribed me clonodine instead. We'll see how that works.
Posted by SLS on April 11, 2018, at 5:55:20
In reply to Re: Why is alcohol the only thing that helps me?, posted by Prefect on April 10, 2018, at 23:46:12
> So my doctor refuses to give me more cloanzepam to ween off the alcohol. She presecribed me clonodine instead. We'll see how that works.
Clonodine can be depressogenic - even in otherwise healthy people. If you get this reaction, you might opt for something else. Do you know if guanfacine is ever used? Both drugs are NE alpha-2a agonists.
Carbamazepine (Tegretol) and oxcarbazepine (Trileptal), both of which are anticonvulsants, are used to ease alcohol withdrawal. Perhaps you can research this.
https://www.ncbi.nlm.nih.gov/pubmed/?term=(carbamazepine+OR+oxcarbazepine)+alcohol+withdrawal
Important side effects:
Carbamazepine: Sedating; agranulocytosis
Oxcarbazepine: Hyponatremia
- Scott
Posted by baseball55 on April 11, 2018, at 18:52:26
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by SLS on April 11, 2018, at 5:55:20
Generally you shouldn't mix benzos and alcohol. This is how many people end up, accidentally or on purpose, killing themselves. Especially not with the quantity of alcohol you've been drinking.
Posted by rjlockhart37 on April 12, 2018, at 23:37:32
In reply to Why is alcohol the only thing that helps me?, posted by Prefect on April 6, 2018, at 14:34:51
whiskey is usally 80 proof alcohol, it bumps dopamine up, but also doing GABA, which is why you get punch of euphoria
benzos ... clonazepam, do not work on dopamine, mainly alprazolam is the one that touches dopamine
Posted by rjlockhart37 on April 12, 2018, at 23:48:48
In reply to Re: Why is alcohol the only thing that helps me?, posted by rjlockhart37 on April 12, 2018, at 23:37:32
when i was being ripped off alprazolam - alcohol - it did help with anxiety, and it helped withdrawls, f*ck those doctors they were worse in letting suffer, i've found other resorted treatments too
Posted by bleauberry on April 13, 2018, at 9:01:30
In reply to Re: Why is alcohol the only thing that helps me? » bleauberry, posted by Prefect on April 9, 2018, at 20:13:00
I understand your surprise and curiosity. It happened to me too after 20+ of psychiatric meds, a dozen psychiatrists, multiple diagnosis and all of them bad, failed ECT, failed backpacks full of prescriptions, total cost wasted estimated in the $120,000 range.
Then a Nurse Practitioner one day said that she has seen Lyme disease patients mistaken as psychiatric and she wondered if that had happened with me.
That was the beginning of a 3 year journey to REMISSION! After all that, remission was possible? Absolutely. You just have to hit the right target.
It is my opinion that most of us here a babble, and most psych patients in general, we are hitting the wrong targets. We are attempting to use psychiatric meds as long-term disease cures. They don't cure any diseases. They are excellent for acute manifestations and short term goals.
There are a ton of myths about Lyme. And antibiotics. I don't know where you got the '6 month' thing but that is one of the myths, one of many, many, many. There is a fair consensus that if you treat Lyme in the early stages - like perhaps within the first 6 months - then you can cure it, but that later Lyme is harder to treat. That is true. Not a myth. The deeper the bacteria dig into cartilage, done marrow, brain tissue, glands, the harder it is to reach them with the immune system or antibiotics.
But late Lyme can be cured. It is just harder. And when remission is reached, it can relapse requiring another round of treatment. Catching it early is definitely a better way to go.
But that often doesn't happen. Many people aren't even aware they had exposure to a tick. Nymph ticks are so small you might not even see it - smaller than a freckle. Half the time a bullseye rash does not happen. Half the time the lab test is wrong - the reason I was sick for 20+ years, including a stay in the psych ward.
If a doctor tests you and says, "I am happy to inform you that your test came back negative and it appears you don't have Lyme" - that is the same thing as sentencing an innocent prisoner to a lifetime in a dungeon with ever-increasing torture with time.
Both of my M.D.s and one N.P. are experts on Lyme. They all told me the same thing - that for every 1 person correctly diagnosed, there are an estimated 9 wrongly diagnosed - they got labelled as Fibromyalgia, Depression, Bipolar, Chronic Fatigue, Anxiety, and sometimes even Lupus and MS. They said nearly every new patient comes to them on psychiatric meds and poorly managed by previous doctors. And that when treatment is done, the psychiatric meds are either at much lower doses or eliminated completely.
In the lyme world, psychiatric meds are useful for short-term assistance. Sometimes they are needed permanently depending on longterm brain damage. For example in my case I know there has been some sort of long term impact in the dopamine system and Ritalin overcomes that. Nothing else could do that for me.
I did not experience any pscyhatric relief from antiobiotics until 1 year in. Remission didn't happen until year 3. The whole time I was on 2-4 antibiotics at a time, rotating every couple of months. There are reasons for that but I don't want to get into all that here.
You asked how would antibiotics work for 20+ years of suffering? Good question! My case is only one of millions and shows that it does work, can work. But how it works is more complicated.
In a nutshell - a stealth unsuspected infection - such as Borellia, Bartonella, Babesia, Mycoplasma (all from ticks and sometimes from cats, mosquitoes, flies, mice) - is going to produce toxins - poop, pee, enzymes, dead body parts, etc - in addition to the systemic inflammation damage to the body, and all of that debris floating around.
THAT stuff is what is jamming up our mood center in the brain. Get rid of that stuff. Antibiotics cause that to happen. When the population levels of pathogenic creatures are brought down to low levels (I think eradication is impossible) you no longer have symptoms. No more debris in the brain. Minimal anyway. Co-exist.
So longterm antibiotics work by two hypothesis:
1. Stop the source of the debris hitting the brain, the debris that is squashing out good mood chemicals or contaminating them....
2.Re-setting the immune system. My first LLMD had his own theory that antibiotics work by allowing the immune system to rest for some time. During that rest it can recover and reset. The immune system is intricately tied to mood. As anyone has noticed whenever they catch a flu or virus...It all is quite profound the first time you hear of this. I get that. Been there done that.
> I'm not sure I understand this lyme angle. I've been suffering from various form of this for 20 years. My understanding is antibiotics onlt work for lyme in the first 6 months of infection. You're proposing I go on antibiotics for a possible lyme infection after 20 years? Would it even work now?!
Posted by bleauberry on April 13, 2018, at 9:15:02
In reply to Re: Why is alcohol the only thing that helps me? » bleauberry, posted by Prefect on April 10, 2018, at 11:18:47
Bartonella! Wow. Ok. Of all the various pathogenic creatures from ticks, Bartonella is the one with the most profound psychiatric presentation, in my opinion. And it is not as easy to treat as the others.
I am on antibiotics right now for Bartonella, and Lyme in general, but with focus on Bartonella. Relapse. This relapse is different for me - mostly trembling and stage fright but not deep depression. A combination that really turned the corner for me, twice, concerning Bartonella, has been Doxycycline plus Rifampin. Rifampin is generally a turberculosis med. But it happens to have good efficacy against Bartonella.
When it comes to dopamine agonists, antagonists, stimulants, whatever, my experience has shown me that armchair quarterbacking is not usually real helpful. It can help steer us in a certain direction but not useful for the actual drug choice.
Would Ritalin be more helpful or would Ability be more helpful? Dunno. Only a personal trial would answer that question. That said, my doctor said she prescribes Ritalin more frequently than any other medication because it helps so many more people with so many more symptoms than any other med on the market. I don't think anyone will ever say that about Ability. ???
Armchair quarterbacking did lead me to Prozac+Zyprexa+Modafinil which was a good combination that kept me functional and fairly well, but not remission, for several years. Studies at PubMed led me directly to that combo. It worked good for a while. But a personal trial was the only way to find out. Eventually lyme symptoms were able to overwhelm the meds and they pooped.
My doc said Ritalin might help me because I flunked the ADHD questionnaire badly. But because of armchair quarterbacking, I was afraid to start it - anxiety was already an issue - I couldn't fathom the idea of adding a stimulant on top of anxiety! But my armchair quarterbacking was completely wrong - Ritalin turned out to be the best anti-anxiety med I ever tried! Totally relaxed, totally focused, and lots of energy for multitasking. The exact opposite of what I thought would happen.
> BTW I should mention I've tested positive for Bartonella not even through a specialized testing lab but a public health lab.
>
> You mention Ritalin, would low dose abilify not rebalance dopamine levels as well? It's a D1 agonist.
Posted by bleauberry on April 13, 2018, at 10:01:10
In reply to Re: Why is alcohol the only thing that helps me? » bleauberry, posted by Prefect on April 10, 2018, at 12:21:03
> Also I have a lot of inner tension, tachycardia, and sensory agitation. Would Ritalin not make this worse, because it's also a norepinephrine reuptake inhibitor. I went on Fetzima last year for a weak and it turned me into a basketcase.
Wow. You are offering a very good description of what Bartonella feels like. Excellent choice of descriptive words. Accurate.
I don't know anything about your case. Looking in from the outside, knowing very little, my gut instinct is two-fold:
1. Find a med(s) as quick as you can that just helps your symptoms feel better - don't worry about a cure or perfection at this point - you just need improvement at this point. Whether it is Xanax or Ritalin or SSRI or antipsychotic, to me, really doesn't matter. What does matter is that you are more functional than you were, more relaxed than you were.
2. Find an LLMD.Because the real thing that needs to happen is to address the Bartonella and its likely tag-team of friends - they are causing your psychiatric symptoms - in my opinion.
In terms of psychiatry, Bartonella is often associated with:
1. over sensitive to random meds, requiring tiny doses
2. under sensitive to random meds, requiring massive doses
3.paradoxical reactions where the med makes you worseAs an example, one of my LLMDs starts his depression patients on one drop of liquid lexapro. I personally disagree strongly with any kind of reuptake inhibitors in Lyme, but that's another story. He liked lexapro and said he had a good method. That one drop was the same as 1/10th of 1mg! Some of his patients were making progress from depression with just 1mg to 5mg of lexapro! Because they were so sensitive. I often think the doses are way too high. Just my opinion. I think it is easy to accidentally overshoot a magical window.
A book called Healing Lyme by Stephen Buhner is a fantastic book to orient yourself on the complexities, mysteries, diagnosis and treatment via natural herbs and supplements. This is a great place to start! You can feel better with just some of the anti-inflammation and anti-toxicity strategies. There are potent antimicrobial herbs, including ones for Bartonella.
I think most people eventually need pharmaceutical antibiotics to get over the hump to the finish line. But herbal approaches can get you started on the journey at home while you hunt for the right clinician to help you. You can make a lot of progress before you even see a doctor.
You will want to specifically seek out LLMDs in your state. LLMD stands for Lyme Literate Medical Doctors - these folks have been to special training, seminars, and clinical experience that regular doctors/specialists have not. They are keenly aware of the strong correlation between psychiatry and Lyme, and they can even make educated guesses as to which organism is causing the symptoms based on the description of the symptoms. They know how to make the diagnosis, with or without testing, and they know the ways to treat that work, and the ones that don't work. I actually did some of this on my own for a while by ordering my own antibiotics from overseas pharmacies. I would not suggest anyone else do that. But I did.
I got a head start while I was still hunting for an LLMD. There were none in my state. I had to go the next state over which had 6 of them. That was years ago. My state now has 2 LLMDs and 1 LLNP. Where ever you live, there are probably a handful of them within reach.
Trying to figure out what kind of medication might help you feel better is hard. Will it be a NE med? DA? 5ht? Gaba? Don't know. I think what makes sense to start with meds that work fast - stimulants, benzos, and antipsychotics. The SSRIS and TCAs can take weeks or months of time and end up being a total waste of time often. They can behave badly when Bartonella is present. We can get oversensitive reactions or opposite reactions. SSRIs, for example, or any kind of reuptake mechanism, made my depression worse not better. And the numbness. Yuck.
I think an approach that makes sense in your case is to find the fastest short-term assistance you can get from meds that doesn't require a longtime commitment to see if it helps or not, to study a book or two, to begin treatment with a few select supplements/herbs at home, while hunting for an LLMD. The meds won't ever be your cure, if you ask me. But the LLMD stands a real good chance of being your cure.
Even simple herbal strategies could give you rapid relief of symptoms. I'm thinking Lemon Balm, Passion flower, Chinese Skullcap (Baical Skullcap), American Skullcap, Valerian root, and others. At the natural food store or online buy 2-4 of these are start experimenting with combinations of them. Any combos. herbs work best in combos. The ones I listed here are generally known for their calming properties on the nervous system, and not known for worsening existing depression (valerian could worsen).
I want to share with you one of my profound experiences. Just so you can think about it. This is recent. Last week I had incredible anxiety pop up for no reason. It is sort of like butterflies in the tummy or stage fright. I get lightening bolts of electricity through my heart. Heart palpitations. Fear of going out. Now, I didn't freak out over any of this because I already knew it was 'fake' - not real - a fake way of feeling, caused by infection, most likely Bartonella. Even though it feels horrible and impacted me terribly, I knew deep down where it was coming from. Ok so I see my doctor and she decides to change out antibiotics - one of Borellia regular, one for Borellia L form, one for Borellia Cystic form, and one specific for Bartonella. I do 3 during the week and add the 4th only on weekends (Flagyl - a cyst buster).
So here is what happened on day 2 to day 4: Lightening bolts gone, completely gone. Heart palpitations improved 90%. No fear of going out. Feeling peaceful and hopeful. Day 5 is when the Herx hit (die-off) which brought all the original symptoms back. I stopped a day to let my body catch up clean out the toxicity of death. Great peace again. And today back on meds. And so goes the battle. I symbolically compare it to peeling layers of onions. It goes like this: Meds cause improvement, but then it gets blown up by a Herx, then stop to rest, then restart for more improvement, then Herx, then stop again, then start again...and with each new layer the time of 'peace' or 'remission' gets longer and longer. At first maybe it's just half a day. Then next time it's a while day. Then next time it's 2 whole days. Then next time it's almost a whole week. And then as time goes by, the good days greatly outnumber the bad days, Herxing hardly ever happens anymore, much milder when it does, and progress is remarkable.
It is a hard fight I will tell you that. But there is a harder fight that doesn't end with remarkable progress. That's the fight we are in here, trying to choose the best psychiatric med.
That is my experience and opinion.
Posted by Prefect on April 13, 2018, at 13:17:46
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by bleauberry on April 13, 2018, at 10:01:10
You sound very knowledgable bleaberry.
My doctor has prescribed me 0.1 mg of clonidide twice a day to help me withdraw from alcohol. It doesn't even make a dent. I give up by 2 pm after hours of inner tension, shaking, and derealization and have a couple of shots of whiskey and almost feel human again.
I should tell you another interesting fact. ex-wife and I conceived 4 times only 3 years ago (three miscarried, 4th made it and is the love of my like and the only thing keeping me from committing suicide). And yet lab tests recently show all my pituitary hormones have suddenly tanked. They're at the level of someone 50 years older than me. I'm not sure if it's related or not, but it's a little baffling. Testosterone is supposed to only fall 1% a year. Mine have tanked very suddenly.
Posted by SLS on May 1, 2018, at 7:21:33
In reply to Re: Why is alcohol the only thing that helps me? » bleauberry, posted by Prefect on April 13, 2018, at 13:17:46
Trilepal (oxcarbazepine) is supposed to reduce the withdrawal effects of alcohol discontinuation. Trileptal is an anticonvulsant used for epilepsy and as a mood stabilizer.
It sounds like alcohol is disinhibiting you (your brain) in some way. This might be why you feel better when you drink it. Disinhibition is common, but it looks different in each person.
Can you describe how you feel when you are depressed?
In what ways does alcohol make you feel better?
- Scott
Posted by Prefect on May 1, 2018, at 17:59:20
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by SLS on May 1, 2018, at 7:21:33
I've had a relapse of a neuropsychaitric syndrome I had 20 years ago: Anxiety, derealization, executive functioning issues, no concentration, it's like I'm in a catatonic anxious daze that causes me to lose touch with reality most of the day. Oh and hands and eyeballs tremor (yes, eyeballs, opthomalogist has confirmed this is in fact happening but can;t explain it). I fully check out when people try to engage me in conversation.
Alcohol put me in full remission. I can focus better, I can socialize, even the mild weakness in my limbs and tremor is fully gone. BTW I did a home detox 3 weeks ago and have been alcohol free since then, not even craving it. I'm just craving the remission state it put me in.
This is why I'm fascinated by bleauberry's dopamine dysfunction theory. Diazepams don't help at all, so it must be some mechanism of alcohol that's nothing to do with GABA. Either dopamine or opioid system.
Posted by SLS on May 2, 2018, at 23:51:57
In reply to Re: Why is alcohol the only thing that helps me?, posted by Prefect on May 1, 2018, at 17:59:20
Have you ever tried Lamictal, Abilify, or Wellbutrin? This makes a pretty decent dopamine cocktail.
- Scott
Posted by Prefect on May 6, 2018, at 6:01:33
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by SLS on May 2, 2018, at 23:51:57
by cocktail you mean I'd take all three of them?
Posted by SLS on May 6, 2018, at 9:12:12
In reply to Re: Why is alcohol the only thing that helps me? » SLS, posted by Prefect on May 6, 2018, at 6:01:33
> by cocktail you mean I'd take all three of them?
Yes.
Lamictal, Wellbutrin, Abilify (Effexor)
There are several people I know who were treatment resistant who responded favorably to these three drugs taken together. Of course, you might not react the same way. You can line up 10 people, and get 10 different reactions to the same one drug. Another drug that can be added to the other three is Effexor. Each drug helps to stabilize
People recommending one treatment or another will have their favorites to promote. I like these drugs because they work. Why they work would be difficult to ascertain at this point given the current state of neuroscience. However, an argument can be made that these drugs help to increase dopamine function either directly or indirectly. If these drugs don't work for you or produced intolerable side effects, this information would be useful when refining future treatments. As far as I can tell, there are no serious interactions between these drugs.
How are you feeling right now? I'm thinking that taking a mood stabilizer might help. The ones I'm thinking of include Tegretol, Trileptal, and Lyrica. Maybe Depakote. The goal here is to use one of these as a replacement for the pro-GABA effects of alcohol.
- Scott
Posted by Prefect on May 11, 2018, at 17:58:24
In reply to Re: Why is alcohol the only thing that helps me? » Prefect, posted by SLS on May 6, 2018, at 9:12:12
I've been off alcohol for a month and not even craving it. But my mood disorder and symptoms remain. I'm tapering down Zoloft and may start Trintellix in a couple of weeks. Meanwhile I'm using this SSRI lull (at 50 mg zoloft now) to try CBD oil. Took my first dose today.
Posted by Phillipa on May 11, 2018, at 18:17:58
In reply to Re: Why is alcohol the only thing that helps me? » SLS, posted by Prefect on May 11, 2018, at 17:58:24
What if CBD oil could eradicate alcholism and also withdrawal from SSRI and eliminate need for benzos? Did you buy it or need an RX? Thanks Phillipa
Posted by SLS on May 11, 2018, at 22:21:07
In reply to Re: Why is alcohol the only thing that helps me? » SLS, posted by Prefect on May 11, 2018, at 17:58:24
> I've been off alcohol for a month and not even craving it. But my mood disorder and symptoms remain. I'm tapering down Zoloft and may start Trintellix in a couple of weeks. Meanwhile I'm using this SSRI lull (at 50 mg zoloft now) to try CBD oil. Took my first dose today.
I'll be watching your CBD trial closely. Good luck.
- Scott
This is the end of the thread.
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