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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by porkpiehat on September 20, 2016, at 15:47:53
Effexor trial was making me feel a little too detached and unmotivated but keeping me out of rock bottom. I didn't want to go up to 75 and feel worse but I didn't want to ruin a weeks' vacation with friends and stay locked in a room.
For two weeks, 10mgs (half a capusle) of vyvanse paired really well with the effexor. I didn't feel super wired or sketchy or nervous like I would normally on vyvanse; I was re-interested in my friends and my hobbies and studies; I could concentrate at home and work.
Didn't sleep so well. Now I feel like I'm asleep on my feet all day and then not tired at night. The lift is gone and I'm exhausted.
Before the lift went, this weekend, I got super drinky and smokey (cigs), did an awful lot of stuff, masturbated 7 times in six hours.
Monday I was kind of a shell. Today a shell but barely able to stand. I took a little more Vyvanse in the afternoon and I feel more OK. Don't want to chase this dragon but there's such a thing as an effective dose, right?
Posted by baseball55 on September 20, 2016, at 19:48:18
In reply to Is this Stim tolerance or maybe cycling?, posted by porkpiehat on September 20, 2016, at 15:47:53
I've never taken vyanase, but I have taken ritalin and adder all. Both made me spacey and tired, yet wired and jumpy at the same time. Not at first, but after a taking for a few days, I couldn't wait for them to wear off. I seem to have a paradoxical reaction to stimulants. Maybe you do as well.
Posted by Christ_empowered on September 21, 2016, at 13:43:01
In reply to Re: Is this Stim tolerance or maybe cycling?, posted by baseball55 on September 20, 2016, at 19:48:18
Its weird...stimulants have been around in psychiatry forever, and its still kind of hard to predict who will respond well, who won't, who'll turn psychotic, etc.
I'd lay off the amphetamine until you get a better idea of how effexor by itself treats you, and then maybe reintroduce it.
Posted by porkpiehat on September 21, 2016, at 14:08:03
In reply to Re: Is this Stim tolerance or maybe cycling?, posted by Christ_empowered on September 21, 2016, at 13:43:01
that's good advice, but It was pretty clear how I was responding to effexor, which is why I added the stim to offset the blunting, apathy and sleepiness.
I'm not sure if what's happening to me know is a response to the amphetamine or from the lack of quality sleep.
Posted by J Kelly on September 21, 2016, at 22:52:27
In reply to Is this Stim tolerance or maybe cycling?, posted by porkpiehat on September 20, 2016, at 15:47:53
> Effexor trial was making me feel a little too detached and unmotivated but keeping me out of rock bottom. I didn't want to go up to 75 and feel worse but I didn't want to ruin a weeks' vacation with friends and stay locked in a room.
>
> For two weeks, 10mgs (half a capusle) of vyvanse paired really well with the effexor. I didn't feel super wired or sketchy or nervous like I would normally on vyvanse; I was re-interested in my friends and my hobbies and studies; I could concentrate at home and work.
>
> Didn't sleep so well. Now I feel like I'm asleep on my feet all day and then not tired at night. The lift is gone and I'm exhausted.
>
> Before the lift went, this weekend, I got super drinky and smokey (cigs), did an awful lot of stuff, masturbated 7 times in six hours.
>
> Monday I was kind of a shell. Today a shell but barely able to stand. I took a little more Vyvanse in the afternoon and I feel more OK. Don't want to chase this dragon but there's such a thing as an effective dose, right?I've had a similar response to Ritalin. At first I feel great, motivated with lots of energy. But I find that I always need ever increasing doses to keep the same effect. Chasing the dragon as you say. Great for a two week vacation, not so great for long term use in my experience.
Jade
Posted by SLS on September 22, 2016, at 6:43:30
In reply to Re: Is this Stim tolerance or maybe cycling? » porkpiehat, posted by J Kelly on September 21, 2016, at 22:52:27
> > Effexor trial was making me feel a little too detached and unmotivated but keeping me out of rock bottom. I didn't want to go up to 75 and feel worse but I didn't want to ruin a weeks' vacation with friends and stay locked in a room.
> >
> > For two weeks, 10mgs (half a capusle) of vyvanse paired really well with the effexor. I didn't feel super wired or sketchy or nervous like I would normally on vyvanse; I was re-interested in my friends and my hobbies and studies; I could concentrate at home and work.
> >
> > Didn't sleep so well. Now I feel like I'm asleep on my feet all day and then not tired at night. The lift is gone and I'm exhausted.
> >
> > Before the lift went, this weekend, I got super drinky and smokey (cigs), did an awful lot of stuff, masturbated 7 times in six hours.
> >
> > Monday I was kind of a shell. Today a shell but barely able to stand. I took a little more Vyvanse in the afternoon and I feel more OK. Don't want to chase this dragon but there's such a thing as an effective dose, right?
>
> I've had a similar response to Ritalin. At first I feel great, motivated with lots of energy. But I find that I always need ever increasing doses to keep the same effect. Chasing the dragon as you say. Great for a two week vacation, not so great for long term use in my experience.
>
> JadePorkpiehat, Have you experienced this type of switch in mood before? Is there any bipolarity in your family? If there is, it may change treatment strategies. If not, then desipramine or nortriptyline might be worth trying. You can simply add one of these to Effexor so that you won't go without some coverage. If ADHD/ADD is involved, I would go with desipramine.
Some people, including myself, find Focalin (dexmethylphenidate) smoother and more consistent than Ritalin (methylphenidate). Whatever it takes. Vyvanse (lisdexamfetamine) was not at all helpful to me.
What illness and symptoms are you trying to treat? In some situations, Provigil or Nuvigil help with anergic and cognitive symptoms. If word-finding impairments are particularly problematic, Namenda (memantine) often helps.
- Scott
Posted by porkpiehat on September 26, 2016, at 20:26:35
In reply to Re: Is this Stim tolerance or maybe cycling?, posted by SLS on September 22, 2016, at 6:43:30
I have had that sudden uptick in mood before on different medications.Is it not possible to have sensitivities to drugs without a bipolar dx...especially in trauma?
I'm going to look at memantine, but in doing some thinking and research I'm pretty sure the effexor is the reason for the insomnia and daytime sleepiness.
This is the end of the thread.
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