Psycho-Babble Medication Thread 1002060

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Coffee, Caffeine + Risk Of Depression In Women

Posted by Phillipa on November 9, 2011, at 20:14:08

What if you get anxious when drinking caffeine? Also why do psych wards not allow caffeine? Phillipa

Medline:
Arch Intern Med. 2011; 171(17):1571-8 (ISSN: 1538-3679)
Lucas M; Mirzaei F; Pan A; Okereke OI; Willett WC; O'Reilly ÉJ; Koenen K; Ascherio A
Department of Nutrition, Harvard School of Public Health, and Department of Medicine, Brigham and Women's Hospital, 655 Huntington Ave, Boston, MA 02115, USA.

BACKGROUND: Caffeine is the world's most widely used central nervous system stimulant, with approximately 80% consumed in the form of coffee. However, studies that analyze prospectively the relationship between coffee or caffeine consumption and depression risk are scarce.

METHODS: A total of 50,739 US women (mean age, 63 years) free of depressive symptoms at baseline (in 1996) were prospectively followed up through June 1, 2006. Consumption of caffeine was measured from validated questionnaires completed from May 1, 1980, through April 1, 2004, and computed as cumulative mean consumption with a 2-year latency period applied. Clinical depression was defined as self-reported physician-diagnosed depression and antidepressant use. Relative risks of clinical depression were estimated using Cox proportional hazards regression models.

RESULTS: During 10 years of follow-up (1996-2006), 2607 incident cases of depression were identified. Compared with women consuming 1 or less cup of caffeinated coffee per week, the multivariate relative risk of depression was 0.85 (95% confidence interval, 0.75-0.95) for those consuming 2 to 3 cups per day and 0.80 (0.64-0.99; P for trend<.001) for those consuming 4 cups per day or more. Multivariate relative risk of depression was 0.80 (95% confidence interval, 0.68-0.95; P for trend=.02) for women in the highest (&#8805;550 mg/d) vs lowest (<100 mg/d) of the 5 caffeine consumption categories. Decaffeinated coffee was not associated with depression risk.

CONCLUSIONS: In this large longitudinal study, we found that depression risk decreases with increasing caffeinated coffee consumption. Further investigations are needed to confirm this finding and to determine whether usual caffeinated coffee consumption can contribute to depression prevention.

Major Subject Heading(s) Minor Subject Heading(s)

PreMedline Identifier: 21949167
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

 

Re: Coffee, Caffeine + Risk Of Depression In Women

Posted by gadchik on November 10, 2011, at 6:28:17

In reply to Coffee, Caffeine + Risk Of Depression In Women, posted by Phillipa on November 9, 2011, at 20:14:08

I know it sucks.Coffee helps depression,but can cause anxiety.So the anxious,depressed people dont know what to do.I used to drink 3 cups a day,and got a boost.But since my anxiety came roaring back,I can only drink 1/2 cup,mostly milk.My klonopin doesnt do well w/caffeine.But I love that 1/2 cup 1st thing everyday!

 

Re: Coffee, Caffeine + Risk Of Depression In Women » gadchik

Posted by Phillipa on November 10, 2011, at 19:20:57

In reply to Re: Coffee, Caffeine + Risk Of Depression In Women, posted by gadchik on November 10, 2011, at 6:28:17

Believe it not there was a period in my life when stable with a husband and job did take xanax for sleep but could drink a full pot of coffee and grind own beans each morning. Even a time when working 3-11 drank about a pot and with the small dose of xanx went right to sleep an hour after getting home. I wonder what causes these changes in body chemistry? Phillipa

 

Re: Coffee, Caffeine + Risk Of Depression In Women » gadchik

Posted by psychobot5000 on November 14, 2011, at 12:36:08

In reply to Re: Coffee, Caffeine + Risk Of Depression In Women, posted by gadchik on November 10, 2011, at 6:28:17

> I know it sucks.Coffee helps depression,but can cause anxiety.So the anxious,depressed people dont know what to do.I used to drink 3 cups a day,and got a boost.But since my anxiety came roaring back,I can only drink 1/2 cup,mostly milk.My klonopin doesnt do well w/caffeine.But I love that 1/2 cup 1st thing everyday!

First, Phillipa, thanks for posting this--it's interesting.

Gadchik, I have some advice that might (or might not) be helpful. Have you tried switching to tea? Tea has caffeine to, of course, though less than coffee, but its load of caffeine comes leavened with chemicals that relieve anxiety at least a little, like theanine and perhaps some of the polyphenols. Some people, like myself, can tolerate a cup of tea when coffee makes them too edgy--coffee actually has some chemicals beside caffeine that INCREASE the anxiety you feel--they're GABA-A inverse agonists, if I remember correctly. A little like the opposite of a benzodiazepine.

Anyway, if you can't do coffee, tea is worth a try. There are thousands of papers in Japanese and Chinese about its health benefits.

 

Re: Coffee, Caffeine + Risk Of Depression In Women » psychobot5000

Posted by ed_uk2010 on November 14, 2011, at 17:06:58

In reply to Re: Coffee, Caffeine + Risk Of Depression In Women » gadchik, posted by psychobot5000 on November 14, 2011, at 12:36:08

Too much coffee makes me feel unwell, tea does not have this effect.

 

Re: Coffee, Caffeine + Risk Of Depression In Women

Posted by Phillipa on November 14, 2011, at 19:45:58

In reply to Re: Coffee, Caffeine + Risk Of Depression In Women » psychobot5000, posted by ed_uk2010 on November 14, 2011, at 17:06:58

I also drink tea. It's okay no problem. Phillipa


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