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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by floatingbridge on November 17, 2010, at 16:18:20
I had a terrible increase in pain when I trialed strattera, an nri and even experienced new symptoms, like headaches.
Today is a high pain day w/ headache. Headaches are unusual for me. I am trialing cymbalta 30mg since Friday. (The first few days were promising.)
I haven't given up yet. I've a message out to my pdoc.
Please, any thoughts? Theory?
Posted by morgan miller on November 17, 2010, at 20:04:52
In reply to why might an nri or snri not work for someone, posted by floatingbridge on November 17, 2010, at 16:18:20
Wish I had the answers. I'm just not knowledgeable enough with neurochemistry to make a good guess. My best guess would be that you have a sensitivity to drugs that boost levels of norepinephrine. I think I do.
It is very early FB. Hopefully in a week or two this minor setback will just me a memory.
Posted by Phillipa on November 18, 2010, at 0:32:25
In reply to Re: why might an nri or snri not work for someone, posted by morgan miller on November 17, 2010, at 20:04:52
FB the med is building up in your system. I had head pressure second round with cymbalta. Didn't want to say took twice as second time had to quit. But you say you are have a hard time coming off pristiq right? Could it be withdrawal? Love Phillipa
Posted by floatingbridge on November 18, 2010, at 11:00:46
In reply to Re: why might an nri or snri not work for someone, posted by Phillipa on November 18, 2010, at 0:32:25
There is alot going on, so it could be withdrawal. Sigh.
I am sticking it out. Yesterday brought back memories of the strattera trial :(
Wish I understood the science of it all.
Wait. I wish I didn't have depression :)
Thanks Morgan and Phillipa.
Posted by PartlyCloudy on November 19, 2010, at 7:08:47
In reply to Re: why might an nri or snri not work for someone, posted by floatingbridge on November 18, 2010, at 11:00:46
I've had a hard time starting medications because of really poor experiences in the past - enough to make me avoid starting something new at all. It's also hard to read about others' responses with meds when they don't jive at all with what we are going through. (Makes me understand a bit more how daunting a pdoc's job is, though - sheesh.)
I read on another thread that you are finding the Cymbalta to be activating and perhaps giving you some relief from your pain - I hope that you can manage the first and rejoice in the second :-)
And goddess bless all our different synapses and how they decide to react to our medications...
pc
Posted by floatingbridge on November 19, 2010, at 10:12:18
In reply to Re: why might an nri or snri not work for someone » floatingbridge, posted by PartlyCloudy on November 19, 2010, at 7:08:47
thanks pc :)
I might actually improve on cymbalta. Yesterday I felt like moving, and that means walking and stretching (exercise!). It's like I had fallen off of the earth, and this could stop it, plus some.
So one week in, feeling wobbly and positive.
(I try not to alarm myself w/ others' symptoms. I was comparing to one prior bad experience of mine....)
I hope cymbalta is treating you well (?) and thanks for your support(!).
fb
Posted by PartlyCloudy on November 20, 2010, at 10:21:30
In reply to why might cymbalta work? » PartlyCloudy, posted by floatingbridge on November 19, 2010, at 10:12:18
> thanks pc :)
>
> I might actually improve on cymbalta. Yesterday I felt like moving, and that means walking and stretching (exercise!). It's like I had fallen off of the earth, and this could stop it, plus some.
>
> So one week in, feeling wobbly and positive.
>
> (I try not to alarm myself w/ others' symptoms. I was comparing to one prior bad experience of mine....)
>
> I hope cymbalta is treating you well (?) and thanks for your support(!).
>
> fbI'm feeling pretty activated on the 30mg. My mornings have me feeling waaaay energized and I am trying to take advantage of having some oomph in me. At the same time, I'm scatter brained from waking up from the Remeron and not enjoying that aspect, so I'm having to make lists to keep myself reigned in.
The day just doesn't play out very smoothly yet. I find that I become very tired in the evening, and have been experimenting with my caffeine intake to manage it. Last night was somewhat of a disaster where I was lying in bed for 2 hours waiting for sleep that just couldn't overcome all the tea I'd had during the day. I ended up taking that extra 100mg dose of Seroquel that I keep in reserve when I have really messed up my sleep. It kicked in quickly and off I went.
So today I am tired and have a medication hangover :-( It will take a while for everything to even out if past experiences are repeated. My body tends to be a slow learner.
I am very happy, though, to be free of my chronic back pain, and of my suicidal ideations.
I hope you have a good weekend.
pc
Posted by Conundrum on November 20, 2010, at 10:44:38
In reply to Re: why might cymbalta work? » floatingbridge, posted by PartlyCloudy on November 20, 2010, at 10:21:30
I bet you can't wait until Lilly's patent run out and they release the once a day dosing, as a patent extender, that they've probably shelved for just that time. I bet it would keep the amount of drug in the body and energy levels more even through out the day.
> > thanks pc :)
> >
> > I might actually improve on cymbalta. Yesterday I felt like moving, and that means walking and stretching (exercise!). It's like I had fallen off of the earth, and this could stop it, plus some.
> >
> > So one week in, feeling wobbly and positive.
> >
> > (I try not to alarm myself w/ others' symptoms. I was comparing to one prior bad experience of mine....)
> >
> > I hope cymbalta is treating you well (?) and thanks for your support(!).
> >
> > fb
>
> I'm feeling pretty activated on the 30mg. My mornings have me feeling waaaay energized and I am trying to take advantage of having some oomph in me. At the same time, I'm scatter brained from waking up from the Remeron and not enjoying that aspect, so I'm having to make lists to keep myself reigned in.
>
> The day just doesn't play out very smoothly yet. I find that I become very tired in the evening, and have been experimenting with my caffeine intake to manage it. Last night was somewhat of a disaster where I was lying in bed for 2 hours waiting for sleep that just couldn't overcome all the tea I'd had during the day. I ended up taking that extra 100mg dose of Seroquel that I keep in reserve when I have really messed up my sleep. It kicked in quickly and off I went.
>
> So today I am tired and have a medication hangover :-( It will take a while for everything to even out if past experiences are repeated. My body tends to be a slow learner.
>
> I am very happy, though, to be free of my chronic back pain, and of my suicidal ideations.
>
> I hope you have a good weekend.
> pc
>
>
Posted by floatingbridge on November 20, 2010, at 10:48:44
In reply to Re: why might cymbalta work?, posted by Conundrum on November 20, 2010, at 10:44:38
Is cymbalta early evening lag notorious?
I thought it was me, maybe. Not sure.
Posted by floatingbridge on November 20, 2010, at 11:07:29
In reply to Re: why might cymbalta work? » floatingbridge, posted by PartlyCloudy on November 20, 2010, at 10:21:30
pc,
I'm working on the timing and daily rhythm, too (along w/everything else! ).
Hope your weekend is good, too, despite the med hangover.
Sounds like you are having excellent results :)
fb
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