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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by france1000 on March 10, 2008, at 22:15:00
Have been taking low dose of Loxapine since one week:
- Before beginning the treatement my heart rate was about 85-90 p./min
Now, with Loxapine my heart rate is about 65-70p./min
Is that a good or bad symptome ???
Someone takes Loxapine too and in combination with wich medication??
Posted by yxibow on March 11, 2008, at 0:36:44
In reply to Loxapine - is it cardiotoxic?, posted by france1000 on March 10, 2008, at 22:15:00
> Have been taking low dose of Loxapine since one week:
>
> - Before beginning the treatement my heart rate was about 85-90 p./min
>
> Now, with Loxapine my heart rate is about 65-70p./min
>
> Is that a good or bad symptome ???
> Someone takes Loxapine too and in combination with wich medication??Sounds more like the Loxapine is helping with your condition, whatever it may be.
90bpm can be uncomfortable for some people
65-70bpm is a perfectly ideal pulse rate.Loxapine is metabolized partially into amoxapine, a tricyclic with antipsychotic properties.
Usually it actually can have a side effect of -increasing- heart rate.
Posted by france1000 on March 11, 2008, at 5:06:14
In reply to Re: Loxapine - is it cardiotoxic? » france1000, posted by yxibow on March 11, 2008, at 0:36:44
> Loxapine is metabolized partially into amoxapine, a tricyclic with antipsychotic properties.THANK YOUR FOR YOUR ANSWER YXBOY;
IF LOXAPINE IS METABOLIZED PARTIALLY INTO AMOXAPINE - IS IT USUAL TO COMBINE AMOXAPINE WITH
ANAFRANIL?
Posted by yxibow on March 13, 2008, at 4:24:36
In reply to LOXAPINE WITH ANAFRANIL?, posted by france1000 on March 11, 2008, at 5:06:14
>
> > Loxapine is metabolized partially into amoxapine, a tricyclic with antipsychotic properties.
>
> THANK YOUR FOR YOUR ANSWER YXBOY;
> IF LOXAPINE IS METABOLIZED PARTIALLY INTO AMOXAPINE - IS IT USUAL TO COMBINE AMOXAPINE WITH
> ANAFRANIL?
>
>I should have said, may metabolize fully, partially, it depends on genetics and a whole lot of other things.
Although Amoxapine can be compared to an antipsychotic in some ways, Loxapine is in the official class of one. Amoxapine is an odd and old member of the tricyclic family that possesses some modest D2 blocking capabilities.
Its not usual these days to prescribe Amoxapine, and combining two tricyclics is generally not a practice due to doubling of anticholinergic effects.
Anafranil can have sweating effects for some so it definately has anticholinergic properties.
I would say it would be a very unusual combination.
This is the end of the thread.
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