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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by linkadge on January 1, 2008, at 12:52:14
http://www.biopsychiatry.com/hyperdopaminergic.html
Linkadge
Posted by clipper40 on January 1, 2008, at 19:44:50
In reply to Hyperdopaminergic mice aren't any happier, posted by linkadge on January 1, 2008, at 12:52:14
True, but at least they have the motivation to get to their goal!
I'd far prefer to have accomplishments and the same amount of happiness than not to have the accomplishments at all.
Posted by linkadge on January 1, 2008, at 20:26:23
In reply to Hyperdopaminergic mice aren't any happier, posted by linkadge on January 1, 2008, at 12:52:14
Perhaps, but it still means that one is willing to work harder for a similar level of with the result.
However, I don't know how satisfaction from sucrose translates to satisfaction from cars, money etc.
Linkadge
Posted by clipper40 on January 1, 2008, at 23:15:43
In reply to Re: Hyperdopaminergic mice aren't any happier, posted by linkadge on January 1, 2008, at 20:26:23
That's true and maybe there's a sense of satisfaction for humans about completion of tasks that wouldn't be there for rats and that wouldn't fall into the definition of happy utilized in the study. (I don't know. I'd have to read the abstract again and I'm just too lazy.)
Posted by amigan on January 2, 2008, at 4:14:39
In reply to Hyperdopaminergic mice aren't any happier, posted by linkadge on January 1, 2008, at 12:52:14
I don't know about mice but excessive dopamine leads to psychosis in humans.
Posted by bleauberry on January 2, 2008, at 18:45:09
In reply to Hyperdopaminergic mice aren't any happier, posted by linkadge on January 1, 2008, at 12:52:14
I do believe dopamine is the final common pathway of antidepressants. There are quite a few science reports on the net that look into that also and agree with varying theories on how dopamine is manipulated by other drugs that don't directly work on dopamine.
But one interesting thing that popped up was that the brain might not be entirely hyperdopaminergic or hypodopaminergic, but that it can be both at the same time except in different parts of the brain. That would explain both the positive and negative symptoms of schizophrenia happening simultaneously, and why some antipsychotics can work on both of those symptoms clusters at the same time by reducing dopamine in some parts of the brain and increasing it in others.
All theory of course, as is all of psychiatry, but interesting to ponder.
This is the end of the thread.
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