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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by dapper on December 10, 2007, at 14:50:19
I read about trivastals effectiveness for some people on here, makes me wonder if I should think about it as an option....Im on wellbutrin 150, effexor 225, and lamictal 200...doc wanted me to switch from wellbutrin to remeron, but one dose of the remeron made me sleep way too much...Should i be thinking about switching out the wellbutrin for trivastal? Isn't it aimed at treating conditions like Parkinsons, and dementia? Isn't it only sold in other countries, unless u buy online?
Posted by Mishal on December 10, 2007, at 22:16:48
In reply to Should I try trivastal?, posted by dapper on December 10, 2007, at 14:50:19
> Should i be thinking about switching out the wellbutrin for trivastal? Isn't it aimed at treating conditions like Parkinsons, and dementia? Isn't it only sold in other countries, unless u buy online?
Right. Trivastal Retard is a Parkinson's med, so what? Many Parkinson's meds are being tried for depresion, ADD and for a number of other disorders too. Piribedil has unique action on both dopamine and noradrenaline receptors. The action seems to be similar to that of Amineptine which once was marketed as an antidepressant. Many users swear Amineptine was the best antidepressant they ever have taken.
Sadly goddamned medico-politics did away with that wonderful med.If you are in U.S you can obtain Trivastal Retard from an online pharmacy with a valid U.S prescription. If I promote it in any other way, that would be in violation of this board rules; something I don't want to try at the moment.
Posted by dapper on December 11, 2007, at 2:14:05
In reply to Re: Should I try trivastal? Why not..? » dapper, posted by Mishal on December 10, 2007, at 22:16:48
Well, I havent found Travistal 'retard' online, even if I had a prescription. If I were to find it, for instance, as Travistal 'substained release' would that be the same thing? And in a cocktail of 225mg effexor, 150mg wellbutrin, and 200mg lamictal, the travistal would basically be replacing the wellbutrin, correct?
Posted by Mishal on December 11, 2007, at 2:36:10
In reply to Re: Should I try trivastal? Why not..?, posted by dapper on December 11, 2007, at 2:14:05
> Well, I havent found Travistal 'retard' online, even if I had a prescription. If I were to find it, for instance, as Travistal 'substained release' would that be the same thing?
Trivastal Retard is the brand name of generic Piribedil. It is a french drug patent owned by Servier.
AFIK, there isn't a sustained release version available. Indian version of Piribedil is Trivastal LA (Long Acting). That would be the med you are going to obtain from online pharmacies I guess.> And in a cocktail of 225mg effexor, 150mg wellbutrin, and 200mg lamictal, the travistal would basically be replacing the wellbutrin, correct?
No. Effexor acts on serotonin receptors too. Lamictal is entirely different though Wellbutrin seems to be similar in paper at least. I hadn't had any luck with Wellbutrin.
Adding a little bit of Strattera to Mirapex would mimic the effects of Trivastal. Again a supposition only.
Posted by cumulative on December 11, 2007, at 4:06:44
In reply to Re: Should I try trivastal? Why not..? » dapper, posted by Mishal on December 11, 2007, at 2:36:10
I'm skirting the edge of the board rules here, but there are sites selling Trivastal Retard, and I'd prefer this instead of the Indian generic, if possible. Indian medications can be kind of shady. Also the release is different -- I think this LA cited a 6 hour half-life.
Posted by Sigismund on December 11, 2007, at 14:38:22
In reply to Re: Should I try trivastal? Why not..?, posted by cumulative on December 11, 2007, at 4:06:44
I'm interested in the formulation that produces least insomnia by being eliminated most quickly.
Any idea what that might be?
I was unclear here
>Also the release is different -- I think this LA cited a 6 hour half-life.
as to your meaning.
Posted by Mishal on December 12, 2007, at 4:01:33
In reply to Re: Should I try trivastal? Why not..?, posted by cumulative on December 11, 2007, at 4:06:44
> I'd prefer this instead of the Indian generic, if possible. Indian medications can be kind of shady. Also the release is different -- I think this LA cited a 6 hour half-life.
Sorry to disagree with you cumulative. If it wasn't for Indian generics, I would have been bankrupted by now.I can't afford the price of Provigil here, so I take MODALERT manufactured by SUN pharma of India. Recently, when my friend brought some real Provigil tabs from U.K. I tried it for a couple of days only to make sure, I am taking the right stuff. With all honesty, I would say Indian generic doesn't differ to original brand by any means.
Other than this: Servier operates in India as Serdia: Once I brought some Stablon from India, and from head to toe it was the same stuff I could buy here as Servier's. Exactly the same med, nothing has been altered.
There might be some low quality molecules for sale in India, but it is their best pharmaceutical companies that offer products over Internet. If the product is made by namely SUN Pharma, Cipla, Ranbaxy, or Dr. Reddies, there is nothing to worry over their quality.
This is not a supposition, but an empirical observation.
Cheers.
Posted by cumulative on December 12, 2007, at 6:32:08
In reply to Re: Should I try trivastal? Why not..? » cumulative, posted by Mishal on December 12, 2007, at 4:01:33
Hi Mishal,
Sigismund,I've gotten good medications from India before too (the Lyrica I got in the same shipment is divine -- I wake up refreshed for once in my life, however might switch to neurontin since I'm still affected in the morning and I hate nothing more than compromised cognitive abilities).
Unfortunately my Trivastal LA, which I've been taking for a week as high as 10+ pills at once, wasn't one of them -- it does absolutely nothing to me. I don't know (sort of doubt) that this is the case for all the trivastal LA in India, but it is for everything I purchased.
I'm still looking forward to trying the other formulation in a few weeks. There's a chance I'm just a nonresponder to the substance I guess, but I feel like I should have at least gotten sick.
I know I should have written about this sooner, or given my primary reason for discouraging the generic stuff, but worries that it would discourage people here as regards the other formulation, and lingering, hardcore focus/anhedonia difficulties that make it difficult for me to string words together stopped me for some reason.
I'm real sorry about this. I know it was a useless move to not warn people sooner. Still have high hopes for everyone in whatever they want to try. This is only my experience, but for now I can only give my warning against the LA stuff, and possible uneasiness about the product in general. My hopes are still high for myself as well though.
It was never my intention to display first-world snobbishness, either, although having spent three months in an Indian village on the brink of industrialization, I know that the supply-side economics (aka very little regulation) produces some pretty bad products.
Peace,
Nick
Posted by Mishal on December 12, 2007, at 7:29:47
In reply to Re: Should I try trivastal? Why not..?, posted by cumulative on December 12, 2007, at 6:32:08
Hi Cumulative,Thanks for your input. I am using the original Trivastal Retard made by Servier. Still I don't think The LA stuff made by SERDIA India should differ a lot. After all Serdia is a subsidiary of Servier, France. The only difference is they like to operate in India in a different name. If you check both Servier and Serdia websites, you can notice SERDIA portal is mirroring that of SERVIER.
BTW, since Trivastal Retard's price here is well within the range of my purse, I don't plan to bring in from India.
I agree with you, there are more wicked chemicals on the loose in Indian domicile. Just an example: The benzo Alprazolam is manufactured by at least 40 listed Indian pharm companies, that makes it impossible for an Indian doc to remember all brand names. When I was in Delhi, the young Doc told me he would never go for other than three bands of it. Namely of Cipla, SUN and Ranbaxy. But to have such a wide range of brands for a single generic is astounding. More interestingly, all these brands should have their markets too in the country, otherwise they are not going to survive. I personally found at least 15 of them with different guys, that is not the end; All gain good results from them.
Posted by bulldog2 on December 12, 2007, at 17:10:16
In reply to Re: Should I try trivastal? Why not..?, posted by cumulative on December 12, 2007, at 6:32:08
> Hi Mishal,
> Sigismund,
>
> I've gotten good medications from India before too (the Lyrica I got in the same shipment is divine -- I wake up refreshed for once in my life, however might switch to neurontin since I'm still affected in the morning and I hate nothing more than compromised cognitive abilities).
>
> Unfortunately my Trivastal LA, which I've been taking for a week as high as 10+ pills at once, wasn't one of them -- it does absolutely nothing to me. I don't know (sort of doubt) that this is the case for all the trivastal LA in India, but it is for everything I purchased.
>
> I'm still looking forward to trying the other formulation in a few weeks. There's a chance I'm just a nonresponder to the substance I guess, but I feel like I should have at least gotten sick.
>
> I know I should have written about this sooner, or given my primary reason for discouraging the generic stuff, but worries that it would discourage people here as regards the other formulation, and lingering, hardcore focus/anhedonia difficulties that make it difficult for me to string words together stopped me for some reason.
>
> I'm real sorry about this. I know it was a useless move to not warn people sooner. Still have high hopes for everyone in whatever they want to try. This is only my experience, but for now I can only give my warning against the LA stuff, and possible uneasiness about the product in general. My hopes are still high for myself as well though.
>
> It was never my intention to display first-world snobbishness, either, although having spent three months in an Indian village on the brink of industrialization, I know that the supply-side economics (aka very little regulation) produces some pretty bad products.
>
> Peace,
> NickIf you look on the back of the Trivastal LA blister pack it has has the servier stamp. It should be the same molecule with the only difference being the nature of the time release. Possibly poor shipping degraded your meds. It may have been exposed to much heat etc.
Posted by clipper40 on December 12, 2007, at 17:33:37
In reply to Re: Should I try trivastal? Why not..?, posted by bulldog2 on December 12, 2007, at 17:10:16
Do you think it's possible that it really isn't what it says it is? Could it be nothing more than a sugar pill disguised as Trivastal LA? Maybe I'm too cynical.
Posted by bulldog2 on December 12, 2007, at 17:46:47
In reply to Re: Should I try trivastal? Why not..? » bulldog2, posted by clipper40 on December 12, 2007, at 17:33:37
> Do you think it's possible that it really isn't what it says it is? Could it be nothing more than a sugar pill disguised as Trivastal LA? Maybe I'm too cynical.
Possibly..There are a lot of foreign counterfeits out there. I can definitely feel one trivastal LA. It has a stimulating quality that makes me more alert. Hard to believe that 10 are doing nothing with it's effect on NE.
This is the end of the thread.
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