![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Pluto on January 10, 2007, at 4:34:06
Just curious,Have taken Remeron at 30 mg doses. I could handle it. Could it be the same with Seroquel at 25mg? Can anyone compare the sedative effects?
PLS
Posted by Quintal on January 10, 2007, at 10:47:22
In reply to Remeron Vs Seroquel. Which is More Sedating?, posted by Pluto on January 10, 2007, at 4:34:06
High doses of Remeron are actually less stimulating than lower doses because of the stronger noradrenergic (alerting) effects at high doses.
I would say the sedative effects are in the same ballpark but it is impossible to generalize. I think you would find them very similar.
Q
Posted by Phillipa on January 10, 2007, at 11:50:21
In reply to Re: Remeron Vs Seroquel. Which is More Sedating? » Pluto, posted by Quintal on January 10, 2007, at 10:47:22
Not me seroquel sedates me remeron even at low doses does nothing. Love Phillipa
Posted by Quintal on January 10, 2007, at 12:00:35
In reply to Re: Remeron Vs Seroquel. Which is More Sedating? » Quintal, posted by Phillipa on January 10, 2007, at 11:50:21
>Not me seroquel sedates me remeron even at low doses does nothing. Love Phillipa
Remeron has no sedative effect at all for you at any dose? That's unusual. How much Seroquel were you taking?
Q
Posted by cgd092 on January 10, 2007, at 12:22:34
In reply to Re: Remeron Vs Seroquel. Which is More Sedating? » Phillipa, posted by Quintal on January 10, 2007, at 12:00:35
1/4th of the smallest dose of Remeron (7mg?) will make me very, very sleepy. 25mg. of Seroquel will make me sleepy but not as bad as remeron. To me in general, I would say for me, Remeron causes more sleepiness and munchies.
Posted by blueberry1 on January 10, 2007, at 14:20:18
In reply to Remeron Vs Seroquel. Which is More Sedating?, posted by Pluto on January 10, 2007, at 4:34:06
I found remeron more sedating than seroquel. Longer lasting too. It kept me asleep nearly all night. Seroquel only kept me asleep half the night. I used remeron for about 2 years and it always worked. Based on comments here from others, seroquel keeps needing dose increases with some people.
The trick I found with remeron, and I have seen it in psychopharmacology articles, was to keep the dose low, low, low. For example 7.5mg, 1/2 of 7.5mg, or 1/4 of 7.5mg. The lower the dose the more sedating. Weird.
Posted by Quintal on January 10, 2007, at 15:15:40
In reply to Re: Remeron Vs Seroquel. Which is More Sedating? » Pluto, posted by Quintal on January 10, 2007, at 10:47:22
Earlier I wrote:
>High doses of Remeron are actually less stimulating than lower doses because of the stronger noradrenergic (alerting) effects at high doses.
I really meant:
High doses of Remeron are actually less sedating than lower doses because of the stronger noradrenergic (alerting) effects at high doses.
%$*^%! Typos!
Q
Posted by yxibow on January 10, 2007, at 16:23:48
In reply to Re: Correction, posted by Quintal on January 10, 2007, at 15:15:40
> Earlier I wrote:
>
> >High doses of Remeron are actually less stimulating than lower doses because of the stronger noradrenergic (alerting) effects at high doses.
>
> I really meant:
>
> High doses of Remeron are actually less sedating than lower doses because of the stronger noradrenergic (alerting) effects at high doses.
>
> %$*^%! Typos!
>
> QThis is supposedly a general idea but I don't believe I ever saw that -- highest was 52.5 I think -- maybe the few who can stand 90mg of Remeron can get that.
Seroquel is by far the most sedating of the two but its half life is much less and generally taken at night so its sedation wears off earlier in the day for those who can get by with single dosing. Still residual sedation with Seroquel, if I can remember anything about Remeron, I would say that Seroquel is still more sedating.
But interestingly enough at higher doses, Remeron acts partially like Seroquel with a 5HT blockade for some in addition to Remeron's alpha adrenergic quality, so maybe that's your question here. I first took Remeron with multiple split doses to minimize the sedation but eventually started to combine them. So there is sedation with both I'm afraid. But Remeron, a tetracyclic, is still a very good antidepressant for MDD provided one heeds a restrictive diet/food intake due to its significant weight gain factor which may not go away at high doses. As they say, your miles may vary.-- Jay
Posted by Phillipa on January 10, 2007, at 18:58:45
In reply to Re: Remeron Vs Seroquel. Which is More Sedating? » Phillipa, posted by Quintal on January 10, 2007, at 12:00:35
Q well I waw in the hospital and that night they gave me a total of l00mg of seroquel and l5mg of remeron with chloral hydrate and xanax. I have the constitution of a horse when it comes to sleep. Love Phillipa
Posted by Karen44 on January 10, 2007, at 21:04:38
In reply to Remeron Vs Seroquel. Which is More Sedating?, posted by Pluto on January 10, 2007, at 4:34:06
My pdoc says Seroquel is supposedly more sedating; for me I have to cut the 25 mg. tablet in half because I cannot function the next day if I take 25 mg. at night to help me sleep.
Karen44
>
> Just curious,
>
> Have taken Remeron at 30 mg doses. I could handle it. Could it be the same with Seroquel at 25mg? Can anyone compare the sedative effects?
>
> PLS
Posted by ronaldo on January 12, 2007, at 14:07:44
In reply to Remeron Vs Seroquel. Which is More Sedating?, posted by Pluto on January 10, 2007, at 4:34:06
Hi Pluto
I tried Seroquel for insomnia. 25 mg and above did not overcome the rebound insomnia from Zyprexa w/d. The closest I came to getting some sleep out of it was when I cut a 25 mg tablet into four pieces and took +/- 6.25 mg. That made the room revolve briefly but did not send me to sleep. I don't know which to blame, the Seroquel or the fierce rebound insomnia. But the Seroquel did not make me sleep, not at any dose from 6.25 mg to 100 mg, nothing doing.
ronaldo
Posted by Sadaiya on January 15, 2007, at 10:27:01
In reply to Re: Remeron Vs Seroquel. Which is More Sedating? » Pluto, posted by ronaldo on January 12, 2007, at 14:07:44
Ok.. I had "substance induced sleep disorder".. and i never found out what substance it is that did that to me.. BUT I was taking i think 200 mg of seroquel for sleeping plus 160mg of geodon nightly. But I was able to replace both with Remeron alone.
Remeron did wonders for me with sleeping, with 15 mg alone i was able to replace everything else..
Although supposedly Remeron is less sedating at higher doses, I find this to not entirely be true.
Because what happened to me is that my 15 mg remeron stopped working for a while, so I took 30 mg and it got me to sleep, and I slept longer too..
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.