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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by AMD on May 30, 2005, at 14:21:35
Folks,
I took Zyprexa last weekend (~seven days ago), at a dose of 2.5 mg, then 10 mg, then 2.5 mg. As of today, I still feel 'icky' and chubby (!), as if my metabolism ground to a halt. Now that I've stopped the medicine, how long can I expect these symptoms to last? Is this a permanent change from the medicine? Will I revert to normal? Finally, does these latent effects indicate I may have gotten diabetes from the drug?
Thanks,
amd
Posted by Maxime on May 30, 2005, at 15:06:50
In reply to ZYPREXA HELL!, posted by AMD on May 30, 2005, at 14:21:35
Hi, you will lose any weight you have gained. You will want to exercise to speed things up. You only took it for such a short time it's impossible that you would develop diabetes that quickly from it.
Why didn't you stay at 2.5 for longer? You really increased significantly? What was it prescribed for?
Maxime
> Folks,
>
> I took Zyprexa last weekend (~seven days ago), at a dose of 2.5 mg, then 10 mg, then 2.5 mg. As of today, I still feel 'icky' and chubby (!), as if my metabolism ground to a halt. Now that I've stopped the medicine, how long can I expect these symptoms to last? Is this a permanent change from the medicine? Will I revert to normal? Finally, does these latent effects indicate I may have gotten diabetes from the drug?
>
> Thanks,
>
> amd
Posted by Lynne on May 30, 2005, at 16:00:21
In reply to Re: ZYPREXA HELL! » AMD, posted by Maxime on May 30, 2005, at 15:06:50
Has anyone tried this oral dissovling formulation of Zyprexa? It just dissloves on the tongue. My PDoc said it shouldn't cause the weight gain that the oral capsules do. I have been on 2.5mg for almost a week and I feel FAT!
Posted by Maxime on May 30, 2005, at 16:30:14
In reply to Zyprexa Zydis, posted by Lynne on May 30, 2005, at 16:00:21
> Has anyone tried this oral dissovling formulation of Zyprexa? It just dissloves on the tongue. My PDoc said it shouldn't cause the weight gain that the oral capsules do. I have been on 2.5mg for almost a week and I feel FAT!
Never heard of it. Have you weighed yourself? Have you actually gained weight? Attacked the refridgerator(that's what I did)?
Maxime
Posted by AMD on May 30, 2005, at 16:41:20
In reply to Re: ZYPREXA HELL! » AMD, posted by Maxime on May 30, 2005, at 15:06:50
I was very depressed and in that state threw judgment to the wind and downed four pills. Probably not the smartest move, but I'm glad I stuck at four and didn't down the whole bottle. (This was not a suicide attempt, by the way, but rather a desperate grab for sanity.)
amd
Posted by AMD on May 30, 2005, at 16:43:45
In reply to Re: Zyprexa Zydis » Lynne, posted by Maxime on May 30, 2005, at 16:30:14
Just the thought that it raises blood sugar is enough to turn me off of the medicine. That plus the fact that having taken it at two intervals now, I've realized it just isn't compatible with my body. I've had a strong reaction both times.
By the way, I work out regularly, but despite that felt weight coming on. Or not weight, rather a feeling of decreased muscle mass, increased body fat, and less overall energy. I suspect this was the Zyprexa, and I'm hoping soon it will be completely out of my system with little sequelae.
amd
Posted by AMD on May 30, 2005, at 16:44:50
In reply to Re: Zyprexa Zydis » Maxime, posted by AMD on May 30, 2005, at 16:43:45
I am feeling markedly better today than I was yesterday. The only thing is that my focus is off, my problem solving and planning skills slightly impaired. My mind is racing slightly and I thus feel unable to plan and organize my thoughts and tasks as well as I would like to. I am hoping this is transient.
amd
Posted by Phillipa on May 30, 2005, at 16:59:52
In reply to Re: Zyprexa Zydis » AMD, posted by AMD on May 30, 2005, at 16:44:50
That stupid dumb old pdoc wanted me to take it to help me be hungry. He didn't understand that it was my inability to taste that was a problem. But I definitely would have sued him if I'd taken it and gained wt. He gave me so many wrong meds and totally brainwashed me. And he's the one under investigation right now. Fondly, Phillipa
Posted by Lynne on May 30, 2005, at 20:52:39
In reply to Re: Zyprexa Zydis » Lynne, posted by Maxime on May 30, 2005, at 16:30:14
Maxime, Yes I have weighed myself and gained about 3 lbs in a week. Yes, I attack the Fridge and anywhere else there is food !!! The problem is I like this med but the weight thing will probably make me discontinue it.
Lynne
Posted by med_empowered on May 31, 2005, at 1:49:08
In reply to Re: Zyprexa Zydis, posted by Lynne on May 30, 2005, at 20:52:39
hey! I **hated** zyprexa; at 2.5mgs, I developed awful akathisia. I doubt the zydis tabs will be any better...basically, they're mostly used on people who can't...or, more often, *WON'T*...take the zyprexa. This way, as long as the tab gets in the mouth, that person takes the med. Its the same in terms of side-effects and weight gain and what not...it just dissolves. As for AMD...whenever you take any antipsychotic, it blocks off a good bit of the D2 transmission in your brain. Some of the atypicals, like zyprexa, also block off some serotonin receptors and may also hit up muscarinic (sp?) receptors and affect glutamate...since some of them have kind of long half-lives, it may take a while for all the drug-induced effects to go away, even if you only took the drug for a *brief* amount of time. There's also the possibility of withdrawal issues, but that's way more pronounced in those who have been taking the meds for a good while. For those who have taken high doses of the old antipsychotics, withdrawal effects can include psychosis, even if the person was taking the med for something unrelated to psychosis (old antipsycohtics have been used for anxiety, depression, "neurosis", senile agitation, behavior problems in children, adolescents, and the mentally handicapped, so on and forth.). This occurs because the dopamine blockade causes the development of brand new D2 receptors and makes all the D2 receptors hyper-sensitive; as the D2 blockade wears off and dopamine levels return to normal, a psychosis kind of like amphetamine psychosis can occur because the brain has become hyper-sensitive to dopamine.
This is the end of the thread.
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