![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by ed_uk on December 14, 2004, at 10:48:37
Hello,
Several years ago, thioridazine was one of the most widely prescribed drugs in the UK. Today, it is used only as a second-line treatment for schizophrenia. Its use was restricted due to the risk of serious arrhythmias, especially torsade de pointes.
Thioridazine was popular because it is very cheap and is associated with a low incidence of extrapyramidal side effects. Sadly, it can cause strong peripheral anticholinergic side effects and is more hypotensive than most APs.
Has anyone on psycho-babble taken thioridazine? How did you find it? How did it compare with other APs that you've taken?
Has anyone taken mesoridazine? (Serentil)
Ed.
Posted by Ritch on December 14, 2004, at 13:39:02
In reply to Thioridazine (Mellaril / Melleril), posted by ed_uk on December 14, 2004, at 10:48:37
> Hello,
>
> Several years ago, thioridazine was one of the most widely prescribed drugs in the UK. Today, it is used only as a second-line treatment for schizophrenia. Its use was restricted due to the risk of serious arrhythmias, especially torsade de pointes.
>
> Thioridazine was popular because it is very cheap and is associated with a low incidence of extrapyramidal side effects. Sadly, it can cause strong peripheral anticholinergic side effects and is more hypotensive than most APs.
>
> Has anyone on psycho-babble taken thioridazine? How did you find it? How did it compare with other APs that you've taken?
>
> Has anyone taken mesoridazine? (Serentil)
>
> Ed.
>
>I took it for several years in the late '80's between 10-30mg/day. I liked the stuff, but I got a cataract and some retinal pigmentation from it. Made a great sleeper though. Good next day AD effect. No EPS. The worst side effect from daily use was a very bad stuffy nose (traz was a little like that).
Posted by xbunny on December 14, 2004, at 14:23:55
In reply to Thioridazine (Mellaril / Melleril), posted by ed_uk on December 14, 2004, at 10:48:37
> Hello,
>
> Several years ago, thioridazine was one of the most widely prescribed drugs in the UK. Today, it is used only as a second-line treatment for schizophrenia.>
> Has anyone on psycho-babble taken thioridazine? How did you find it? How did it compare with other APs that you've taken?I used to take thioridazine. As a calming drug I found it very effective, easing the nerves and stopping intrusive thoughts and ruminations. As an antipsychotic I found it less effective having minimal effect on hallucinations and delusions. The side effects were quite acceptable it wasnt too sedating and I didnt get eps or restlessness from it. I stopped it after it use was limited. The nearest drug I have taken to compare it to is chlorpromazine and it was far more tolerable than that. All in to me I think its a shame that its been sidelined I would probably take it again.
Posted by ed_uk on December 14, 2004, at 14:28:05
In reply to Re: Thioridazine (Mellaril / Melleril) » ed_uk, posted by xbunny on December 14, 2004, at 14:23:55
Hi,
In what way did you prefer it to chlorpromazine? I once tried chlorpromazine for anxiety and it caused very severe akathisia.
Regards,
Ed.
Posted by xbunny on December 14, 2004, at 14:38:42
In reply to Re: Thioridazine (Mellaril / Melleril) » xbunny, posted by ed_uk on December 14, 2004, at 14:28:05
Chlorpromazine made me act wacky and made me very restless and jumpy and yet doped at the same time (kinda hard to describe - wired and tired symultaneously). Thioridazine did none of that just made me feel calm and in control of my thoughts. Oh I did get very depressed whilst taking it and prozac. Dont know if that was related to it though.
Posted by jay on December 14, 2004, at 19:53:54
In reply to Thioridazine (Mellaril / Melleril), posted by ed_uk on December 14, 2004, at 10:48:37
> Hello,
>
> Several years ago, thioridazine was one of the most widely prescribed drugs in the UK. Today, it is used only as a second-line treatment for schizophrenia. Its use was restricted due to the risk of serious arrhythmias, especially torsade de pointes.
>
> Thioridazine was popular because it is very cheap and is associated with a low incidence of extrapyramidal side effects. Sadly, it can cause strong peripheral anticholinergic side effects and is more hypotensive than most APs.
>
> Has anyone on psycho-babble taken thioridazine? How did you find it? How did it compare with other APs that you've taken?
>I found Mellaril to have very, very little effect on agitation and major anxiety, while Risperdal, Seroquel, and Zyprexa have helped. It was almost like taking a sugar pill. Mind you, it takes about 2-3 mg's of Risperdal, and 15-20 mg's of Zyprexa to affect me. Many years on these meds seem to build up a bit of tolerance.
Jay
Posted by cubbybear on December 15, 2004, at 5:44:59
In reply to Thioridazine (Mellaril / Melleril), posted by ed_uk on December 14, 2004, at 10:48:37
I don't know if this info will be helpful. I tried Mellaril back in the mid 80s while waiting for MAOI Parnate to kick in against my depression and severe anxiety. So I didn't take it as an AP.
I told my pdoc that it made me feel pretty weird and uncomfortable. I don't recall exactly what happened but I do recall not liking Mellaril at all. I guess I'd concur with what poster Jay said about it.
Posted by Larry Hoover on December 15, 2004, at 22:49:58
In reply to Thioridazine (Mellaril / Melleril), posted by ed_uk on December 14, 2004, at 10:48:37
> Hello,
>
> Several years ago, thioridazine was one of the most widely prescribed drugs in the UK. Today, it is used only as a second-line treatment for schizophrenia. Its use was restricted due to the risk of serious arrhythmias, especially torsade de pointes.
>
> Thioridazine was popular because it is very cheap and is associated with a low incidence of extrapyramidal side effects. Sadly, it can cause strong peripheral anticholinergic side effects and is more hypotensive than most APs.
>
> Has anyone on psycho-babble taken thioridazine? How did you find it? How did it compare with other APs that you've taken?
>
> Has anyone taken mesoridazine? (Serentil)
>
> Ed.I was on Mellaril for a brief period, after I developed psychotic mania from SSRIs. I was put on 200 mg/day. I don't much remember what it was like, other than I finally could sleep again. Years later, I was desperate for something to help me sleep, and I took 25 mg. Bad call! I have no idea how I could have tolerated the higher dose, as that much smaller one was very unpleasant. I threw the remainder in the trash.
Lar
Posted by ed_uk on December 16, 2004, at 6:27:39
In reply to Re: Thioridazine (Mellaril / Melleril) » ed_uk, posted by Larry Hoover on December 15, 2004, at 22:49:58
Hi Larry,
What happened when you took 25mg?
Ed.
Posted by Larry Hoover on December 16, 2004, at 9:56:36
In reply to Re: Thioridazine (Mellaril / Melleril) » Larry Hoover, posted by ed_uk on December 16, 2004, at 6:27:39
> Hi Larry,
>
> What happened when you took 25mg?
>
> Ed.I hardly remember, but I think it was head-spinning stomach-churning disorientation. Plus morning hangover.
Lar
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.