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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by greywolf on September 29, 2004, at 20:17:05
I haven't visited here in a while because I started on Nardil a few months ago and wanted to experience it without prejudging it by other's experiences.I'm now up to only 60mg/day, but I've found it to be somewhat effective with few side effects. The dietary restrictions were no big deal once I committed them to memory, but it does seem to contribute to some weight gain.
I'm curious as to how quickly to push the dosage up. I've been taking it as slow as reasonably possible to allow myself the best chance of adjusting to the med, but the depressive episodes are still pretty severe, though less so than before.
Your thoughts would be appreciated.
Posted by King Vultan on September 29, 2004, at 23:17:17
In reply to Nardil hope, posted by greywolf on September 29, 2004, at 20:17:05
>
> I haven't visited here in a while because I started on Nardil a few months ago and wanted to experience it without prejudging it by other's experiences.
>
> I'm now up to only 60mg/day, but I've found it to be somewhat effective with few side effects. The dietary restrictions were no big deal once I committed them to memory, but it does seem to contribute to some weight gain.
>
> I'm curious as to how quickly to push the dosage up. I've been taking it as slow as reasonably possible to allow myself the best chance of adjusting to the med, but the depressive episodes are still pretty severe, though less so than before.
>
> Your thoughts would be appreciated.I started at 45 mg/day and went to 60 mg/day after two or three weeks. I was at 90 mg/day within two months of starting it. 60 mg/day is more or less the standard effective dose, but there is one school of thought on this drug that says you need 1.0 mg/kg of body weight. For me at about 150 lbs., this figured out to 150/2.2 = 68 mg/day or 5 x 15 pills per day. This was actually the minimum dosage for me that was truly effective. I eventually made it all the way up to 105 mg/day, which I now feel was too much. If I went on the med again, I would shoot for either 75 or 90 mg/day.
If you are still having depressive episodes, I would recommend definitely increasing to 5 x 15 mg/day. I believe you will find it a considerable improvement over 60 mg/day. You may experience an increase in side effects, but I would hope the degree of improvement in antidepressant efficacy would still make it worthwhile.
Todd
Posted by greywolf on September 30, 2004, at 13:08:05
In reply to Re: Nardil hope, posted by King Vultan on September 29, 2004, at 23:17:17
Thanks, Todd. I think it may be a good idea to move up 15mg and see what happens. I have been reluctant to push anything given that I've tried an untold number of other meds over the past 6 years, to no avail longterm.
Posted by jparsell82` on September 30, 2004, at 20:51:29
In reply to Re: Nardil hope, posted by King Vultan on September 29, 2004, at 23:17:17
Do you have any cognitive/memory problems with Nardil? Is the sedation/drowsiness that bad? Just curious, I'm about to start Nardil after everything else failing for me.
Josh
Posted by King Vultan on September 30, 2004, at 21:08:02
In reply to Re: Nardil hope, posted by jparsell82` on September 30, 2004, at 20:51:29
> Do you have any cognitive/memory problems with Nardil? Is the sedation/drowsiness that bad? Just curious, I'm about to start Nardil after everything else failing for me.
>
> Josh
I had zero cognitive or memory problems with Nardil but must say that Parnate is much better for my ADD symptoms. I had fairly severe afternoon drowsiness with Nardil until adding Halcion/triazolam every other night for sleep. I believe the drowsiness was related to the horrific insomnia the stuff caused me at 60 mg/day and above (there were really no therapeutic or adverse effects for me below 60 mg/day). I can't really say that I noticed any sedation related to taking the med itself. It was actually one of the more neutral ones I've taken in that respect.Todd
Posted by ron1953 on September 30, 2004, at 23:26:14
In reply to Nardil hope, posted by greywolf on September 29, 2004, at 20:17:05
Wolf:
Check out the latest and greatest MAIO diet info on this board. The REAL restrictions are nil. I haven't changed my diet one bit since I started Parnate, which has helped my atypical depression tremendously.
Posted by greywolf on October 1, 2004, at 11:34:22
In reply to Re: Nardil hope » jparsell82`, posted by King Vultan on September 30, 2004, at 21:08:02
I haven't had much of a problem with drowsiness. I know that I have a little extra insomnia, but compared to the ridiculous SEs of the SSRIs, NDRIs, SNRIs, etc., Nardil is nothing.Nardil has had a slight sexual SE, but nothing major. In fact, it's a relief after all the problems caused by the numerous other ADs I've been on.
I'm generally absented-minded, so it's probably not right to measure the issue by me, but I've been a little weak on the short term memory stuff since I've been on Nardil. For instance, 3 times in the past few months I've pulled up to a restaurant drive-thru, ordered and paid, then driven straight off without my food. Never, ever did that before.
But if that's the worst inconvenience I face with Nardil, I'm thrilled.
Posted by jparsell82` on October 1, 2004, at 16:32:53
In reply to Re: Nardil hope » jparsell82`, posted by King Vultan on September 30, 2004, at 21:08:02
> > Do you have any cognitive/memory problems with Nardil? Is the sedation/drowsiness that bad? Just curious, I'm about to start Nardil after everything else failing for me.
> >
> > Josh
>
>
> I had zero cognitive or memory problems with Nardil but must say that Parnate is much better for my ADD symptoms. I had fairly severe afternoon drowsiness with Nardil until adding Halcion/triazolam every other night for sleep. I believe the drowsiness was related to the horrific insomnia the stuff caused me at 60 mg/day and above (there were really no therapeutic or adverse effects for me below 60 mg/day). I can't really say that I noticed any sedation related to taking the med itself. It was actually one of the more neutral ones I've taken in that respect.
>
> ToddI tried Parnate. I had to discontinue it after about 3 weeks because I was extremely fatigued and weak. Not sure why... but it was the most sedating antidepressant I've taken. I was looking forward to the "stimulant-like" effects from Parnate too... oh well.
This is the end of the thread.
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