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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by jerimycoplo on April 22, 2004, at 0:57:28
Hi I am going to start Effexor here soon and I was wondering at what dosages effexor 'officially' starts having action on dopamine? Has anyone taken it at those dosages? What happened to you as you increased your dosages and how did it affect you differently as the serontonin , then norepinephrine, and then dopamine kicked in? Is the dopamine effect at the higher dose very weak or average in intensity when compared to say zoloft (which supposedly has a super small effect on dopamine, or compard to
wellbutrin , which is supposed to have a stronger effect on dopamine then zoloft. Did the dopamine effect elicited by the effexor have similarity with the one elicited by wellbutrin (which is stimulating), or is it possible to have dopamine reuptake inhibition without getting the more stimulating - sexually enhancing side effects.
Has anyone noticed the sexual dysfunction caused by the serontonin reuptake in effexor be mediated or eliminated when dosage was raised as the dopamine (and maybe norepineprine) effect kicked in?
thanks
jc
Posted by Sad Panda on April 22, 2004, at 11:31:32
In reply to Effexor dopamine better sex? At what dosage?, posted by jerimycoplo on April 22, 2004, at 0:57:28
> Hi I am going to start Effexor here soon and I was wondering at what dosages effexor 'officially' starts having action on dopamine? Has anyone taken it at those dosages? What happened to you as you increased your dosages and how did it affect you differently as the serontonin , then norepinephrine, and then dopamine kicked in? Is the dopamine effect at the higher dose very weak or average in intensity when compared to say zoloft (which supposedly has a super small effect on dopamine, or compard to
> wellbutrin , which is supposed to have a stronger effect on dopamine then zoloft. Did the dopamine effect elicited by the effexor have similarity with the one elicited by wellbutrin (which is stimulating), or is it possible to have dopamine reuptake inhibition without getting the more stimulating - sexually enhancing side effects.
> Has anyone noticed the sexual dysfunction caused by the serontonin reuptake in effexor be mediated or eliminated when dosage was raised as the dopamine (and maybe norepineprine) effect kicked in?
>
>
> thanks
> jc
>Hi JC,
I believe at around 600mg Effexor starts to fill Dopamine receptors, but thats a fairly ridiculous amount to be taking IMHO. Zoloft hits dopamine receptors at about the same rate that Effexor hits NE recptors, which is possibly the reason it has the highest efficacy of the so called SSRI's.
Cheers,
Panda.
Posted by jerimycoplo on April 22, 2004, at 16:01:52
In reply to Re: Effexor dopamine better sex? At what dosage? » jerimycoplo, posted by Sad Panda on April 22, 2004, at 11:31:32
I heard that the dopamine effect was somewhere at around 350-400 mg a day?! Is there a web page with the info?
jc
Posted by francesco on April 24, 2004, at 17:05:52
In reply to Re: Effexor dopamine better sex? At what dosage? » jerimycoplo, posted by Sad Panda on April 22, 2004, at 11:31:32
Hi Panda, at what dosage Zoloft is supposed to hit dopamine ? 100mg or more ?
Posted by Sad Panda on April 25, 2004, at 0:33:07
In reply to Re: Effexor dopamine better sex? At what dosage? » Sad Panda, posted by francesco on April 24, 2004, at 17:05:52
> Hi Panda, at what dosage Zoloft is supposed to hit dopamine ? 100mg or more ?
>
>I don't know, but I wouldn't go out of my way to go looking for it. 'Emotional flatness' seems to be a common side effect with Zoloft, which probably has something to do with dopamine reuptake inhibition.
Cheers,
Panda.
Posted by francesco on April 25, 2004, at 7:18:11
In reply to Re: Effexor dopamine better sex? At what dosage? » francesco, posted by Sad Panda on April 25, 2004, at 0:33:07
I thought emotional flatness was serotonin-related ! Isn't it ? : o
This is the end of the thread.
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