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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by HappySmurf on April 15, 2004, at 22:19:09
I was somewhat depressive before with anxiety.
Therefore in my stupidity I decided to try an
SSRI. Big mistake...I went from lusy to totaly mentally numb.
I felt hot, tired, no energy, cloudy minded,
anhedonic and sleepy. All this was constant.
I discontinued the SSRI when I first felt the
negative effects, but the negative effects
persisted. I have always felt like this but
after the SSRI`s I felt ten times more like this.The feeling i got was somehow strangely fammiliar,
and reminded me of an serotonin agonist I have
taken occasionally some years ago, namely
psilocybin in the form of mushrooms.
This combined with the physical symptoms (gastric
upset, hyperthermia (also poor temperature
regulation in the extremeties, to hot or to cold),
stress etc pointed towards an overly active
and uninhibited serotonin system.The SSRI`s would perhaps be like pouring more
water in a bathtub wich was already on the verge
of spilling over. Just to make an analogy.
Now due to the anhedonia, observation of my own
behaviour and other factors I decided that my
dopamine system needed a boost.
Enter selegeline with it`s MAO-B inhibition...
Now selegeline worked great and gave me increased
sexual interest and a less submissive social
behaviour (now I don`t take s**t from anyone,
whereas before I would just let it fly.)But I still suspected my serotonin system to be
the real source of my troubles...
I still had the anhedonic numbness wich I found
bearable (zombies don`t complain much).
Certain events in my life tough (girlfrien etc)
made the no-fun, comfortably numb,
hyperserotogenic life I lived to be more of an
non-option.So to cut the story short I decided for the drug
tianeptine after much reading about depressed rats,
stressed tree shrews and just about every research
report on receptors, neurotransmitters etc I could
find. After saying f**k it to my bills and some
hot VISA action I finally got my hands on my first
pack of STABLON tinapetine tabs.About two hours after taking the first pill i felt
a slight shift in my perception and that was about
it. Later that day I still felt tired but not as
severe as normal. Im fact I felt terribly normal
for a welcome change.Later that evening I wound up having sex and much
to my suprise I had a feeling of wanting to never
stop. Now sex in my previous state was always
rather boring and uninteresting. Almost like I
just wanted to get it over with. But this was
different, and no premature anything to*. :D
*(Possible anxiety effect.)BUt it`s a really subtle effect and certainly not
some magic drug wich will make you instantly happy.
But combine this with training ,eating properly and
getting enough sleep my life is on the right track!
I don`t feel happier, but I feel alive and able
to feel all kinds of emotions wich I have not felt
for many years. And that is really great!I want to cry, I want to smile, I want to laugh,
I want to get angry, I want to get sad.
What I don`t want is to be a content with nothing
zombie, devoid of emotion... That`s not life...I write this a couple of weeks into my tianeptine
treatment and things are really good.What am I on?
Selegeline 5mg once a day.
Tianeptine 12,5mg three times a day.Also occasional use of GHB (illegal you say?) as an
make-you-sleep-like-a-log-and-wake-up-really-refreshed
kind of thing, something it does really great.
Posted by ChrisG on April 21, 2004, at 5:08:41
In reply to Tianeptine and selegeline combo., posted by HappySmurf on April 15, 2004, at 22:19:09
Hi Happy Smurf
I am considering the same combination as you, only coming at it from the other direction. I have been on 25mg/day Tianeptine for about 5 months and am considering adding selegiline at 5mg/day. See my post on 20 April titled "Combining Tianeptine and Selegiline".
What did the selegiline do for your motivation (in general, I mean, not just for sex!)? I find the Stablon has made me much less depressed, but I still have no 'go'.
Glad to hear that your social inhibition has lessened, too, because I could do with that.
Do you think there have been any negative interactions at all between the two drugs?
Best wishes
Chris
This is the end of the thread.
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