Psycho-Babble Medication Thread 276176

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what does 5ht2c do ???

Posted by linkadge on November 3, 2003, at 15:52:06

what does 5ht2c do ???

linkadge

Re: what does 5ht2c do ??? » linkadge

Posted by Larry Hoover on November 4, 2003, at 9:15:51

In reply to what does 5ht2c do ???, posted by linkadge on November 3, 2003, at 15:52:06

> what does 5ht2c do ???
>
>
> linkadge

Take what I say with a grain of salt....the whole thing is extremely complex, and looking at a tiny fragment of the complex system may distort what we see.....

The 5-HT2c receptor downregulates dopaminergic and histaminergic neurons. Disturbances in 5-HT2c sensitivity or structural defects are associated both with OCD, and suicidal depression. By an unknown mechanism, 5-HT2c also regulates appetite, and has been associated with both anorexia and obesity.

Lar

Re: what does 5ht2c do ???

Posted by zeugma on November 4, 2003, at 18:57:04

In reply to Re: what does 5ht2c do ??? » linkadge, posted by Larry Hoover on November 4, 2003, at 9:15:51

Some things I've heard about 5HT-2C that are curious:

1) Most drugs which block 5HT-2A also block 5HT-2C;

2) Excessive 5HT-2C agonism has been said to underlies long-term SSRI weight gain.

Take these, not with a pinch of salt, but with the mine it came from :)

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