Psycho-Babble Medication Thread 225951

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what is more potent on dopamine

Posted by den2 on May 11, 2003, at 20:35:13

300 mg of effexor or 100 mg of zoloft?

 

Re: what is more potent on dopamine

Posted by linkadge on May 11, 2003, at 20:58:18

In reply to what is more potent on dopamine, posted by den2 on May 11, 2003, at 20:35:13

Hard to say, but I'd be inclined to say
the Zoloft. There was a chart somewhere
that showed the relative receptor affinities
and Zoloft was quite high.

Linkadge

 

Re: what is more potent on dopamine

Posted by Caleb462 on May 11, 2003, at 22:15:33

In reply to what is more potent on dopamine, posted by den2 on May 11, 2003, at 20:35:13

> 300 mg of effexor or 100 mg of zoloft?

Don't know.... I would love to see a chart that showed reuptake transporter affinities for all the different ADs. That would be awesome. If anybody knows of one, please post link.

I do know, however... that either way (300 mg Effexor or 100 mg of Zoloft), it would be pretty weak.

 

Re: what is more potent on dopamine

Posted by mmcasey on May 12, 2003, at 10:46:58

In reply to Re: what is more potent on dopamine, posted by Caleb462 on May 11, 2003, at 22:15:33

What I know - I am no expert but I did study neuroscience in college and took psychopharm, etc,
in addition to my own personal research -
is that Effexor mostly affects norepinephrine and serotonin a bit, and of course Zoloft
being an SSRI mainly affects serotonin. I'd recommend something that is more
specific for dopamine like Wellbutrin.


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