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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by Squiggles on May 8, 2003, at 8:25:55
Hi,
I don't have any reports yet on my friend
as the increase will take place over the weekend;
however, i am truly curious, does anyone know
(and it's assumed to be true) why this drug
should be more sedating at lower doses and less
so at higher?Anyone with pharmacology background?
Thanks
Posted by djmmm on May 8, 2003, at 8:32:10
In reply to Why is Remeron more sedating at lower doses?, posted by Squiggles on May 8, 2003, at 8:25:55
because it acts as an antihistamine..but at higher doses, norepinephrine is effected, counteracting the sedative effects
Posted by Squiggles on May 8, 2003, at 8:52:51
In reply to Re: Why is Remeron more sedating at lower doses?, posted by djmmm on May 8, 2003, at 8:32:10
You're wonderful :-)
Thanks
Squiggles
Posted by Squiggles on May 8, 2003, at 9:21:11
In reply to Re: Why is Remeron more sedating at lower doses?, posted by djmmm on May 8, 2003, at 8:32:10
I looked up the role of norepinephrine in
depression. I am very sad to say that it
involved the metamorphosis of mice and rats
and the swim-test; i almost puked just thinking
of the state of misery these animals are put
through.Is there no other way to test for mental states -
this is barbaric.Squiggles
This is the end of the thread.
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