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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by lauran on March 15, 2003, at 11:36:01
I am back to taking Seroquel 12.5 mg at bedtime and prn. It has been very successful for me for over one year. My question concerns weight gain.
Does anyone know if weight gain and metabolism change on Seroquel are dose dependent? Some time ago I read that it doesn't matter whether you take 12.5 mg or 600 mg, the weight gain side effect will be just the same for both doses?
I did gain 20 lbs over one year but had also been on Paxil CR for 6 months of that year so cannot pinpoint exactly which med did it. I do exercise and count calories the majority of the time so I know the weight is med related. Losing though and feeling physically better.
Posted by KrissyP on March 15, 2003, at 17:54:53
In reply to Dose dependent wt gain?, posted by lauran on March 15, 2003, at 11:36:01
Hi, you are quite lucky. I take 100mg of Seroquel for sleep. I am glad it has been successful for you:-)
My weight did indeed increase when I started on Seroquel, but it is a wonder drug for me to sleep. I started at 200mg, now I only take the 100mg. Yes, IMHO, metabolism change on Seroquel is dose dependent. My metabolism has totally shut down from this drug, but I still take it for the benefits. I know the weight is med related with me too.
Hope this helped? Please keep me posted:-)
Kristen
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Does anyone know if weight gain and metabolism change on Seroquel are dose dependent? Some time ago I read that it doesn't matter whether you take 12.5 mg or 600 mg, the weight gain side effect will be just the same for both doses?
I did gain 20 lbs over one year but had also been on Paxil CR for 6 months of that year so cannot pinpoint exactly which med did it. I do exercise and count calories the majority of the time so I know the weight is med related. Losing though and feeling physically better.
Posted by Cam W. on March 15, 2003, at 20:24:09
In reply to Dose dependent wt gain?, posted by lauran on March 15, 2003, at 11:36:01
I really don't think that there is any correlation between weight gain and dosage of SSRIs. The same can be said for the atypical antipsychotics.
Across both the SSRI group of antidepressants and the (for lack of a more non-judgemental, PsychoBabblian-new-speak word) "atypical" antipsychotics there does seem to be individual differences in the propensity for each of these psychotropics to be involved weight gain.
Estimates
Posted by Cam W. on March 15, 2003, at 21:02:10
In reply to Re: Dose dependent wt gain?, posted by Cam W. on March 15, 2003, at 20:24:09
Geez, I forget how to post, it's been so long ........
Anyway, my estimates (•••note••• I said "my" "estimates", derived from "my" clinical experience, therefore the following lists are not derived scientifically):
SSRIs & Weight Gain:
Paxil™ (paroxetine) > Zoloft™ (sertraline) > Luvox™ (fluvoxamine) ≥ Effexor™ (venlafaxine) ≥ Celexa™ (citalopram) X "that newer one in which the company who released it showed which comes first: profits or patients; by separating this AD's into isomers, then [GET THIS!] the parent company markets isomer as a revolutionary new antidepressant(!!!?); henceforth I shall ignore this marketing shame and not mention it again."
ATYPICAL ANTIPSYCHOTICS
Clozaril™ (clozaril) >> Zyprexa™ (olanzapine) >> Risperdal™ (risperidone) > Seroquel™ (quetiapine).
I hope that this is of some help. - Cam
Posted by Krissy P on March 15, 2003, at 21:36:40
In reply to Re: Dose dependent wt gain?, posted by Cam W. on March 15, 2003, at 20:24:09
Posted by Krissy P on March 15, 2003, at 21:42:48
In reply to Dose dependent wt gain?, posted by lauran on March 15, 2003, at 11:36:01
Question: Is weight gain a side effect of psychiatric medications?
Answer: The answer is yes, which I realize may not do much for anyone's depression or mine---but it's not all bad news. The brain neurotransmitters affected by these drugs to improve our moods are the SAME brain chemicals that control appetite. The Result: As our depression lifts, our appetites may increase. This is what Prozac did to me.
Just some thoughts:-)
Kristen
Posted by Cam W. on March 15, 2003, at 22:03:39
In reply to Seroquel is not an SSRI (nm) » Cam W., posted by Krissy P on March 15, 2003, at 21:36:40
Posted by Krissy P on March 15, 2003, at 22:14:12
In reply to Re: Seroquel is not an SSRI. Gee, thanks alot! ;^P (nm) » Krissy P, posted by Cam W. on March 15, 2003, at 22:03:39
Posted by lauran on March 16, 2003, at 10:53:12
In reply to Re: Dose dependent wt gain?, posted by Cam W. on March 15, 2003, at 20:24:09
Wow. Hi Cam. Imagine my excitement seeing your name as responding to my post! I've lurked PSB a couple of years prior to starting to post and I've gained so much from your experience and knowledge of medications. I hope you are back?
Thanks for answering my question. I stopped Paxil CR last November, an experience in itself. I had moderate akathesia with Abilify and have now returned to Seroquel. If I understand what you say, different individuals have different weight and metabolism changes to the "atypicals". It will be interesting for me to see my weight reaction to just being on the Seroquel. I track calories and exercise output as to be able to measure progress and not just say, "Gee, I'm eating less". We shall see.
Again, thanks for responding Cam.
Posted by lauran on March 16, 2003, at 10:57:34
In reply to Re: Dose dependent wt gain? » lauran, posted by KrissyP on March 15, 2003, at 17:54:53
Hi Krissy. I'm glad you have found some good relief with the Seroquel. Did you gain a lot of weight? You sound like you are really having some success right now and I am so glad for you. Thanks for your input, it always helps.
Posted by Krissy P on March 16, 2003, at 12:20:40
In reply to Re: Dose dependent wt gain? » KrissyP, posted by lauran on March 16, 2003, at 10:57:34
Hiya lauran:-) thanks for such kind words-your replies always help. Since starting on Seroquel back in Novembner 1999, it is a med I have really stuck with and it helps me sleep. I would say I have gained, just from the med, about 40Lbs. :-( not good but the med works for me and for now, I'm just trying to exercise more, I bought that bike lol, and eat a lot of fish-it feels good. And remember those Omega-3 Fatty Acids are great for our brains:-) I first started on 200mg of Seroquel and now only take 100mg at night. (but last night I took 200mg and I feel like a zombie this am) so back to 100mg only tonight. I shouldn't be self-medicating anyway-I gotta a big problem with that.
Hope to hear back, all the best to you,
Kristen
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Hi Krissy. I'm glad you have found some good relief with the Seroquel. Did you gain a lot of weight? You sound like you are really having some success right now and I am so glad for you. Thanks for your input, it always helps.
Posted by KrissyP on March 18, 2003, at 12:28:27
In reply to Re: Seroquel is not an SSRI. Gee, thanks alot! ;^P (nm) » Krissy P, posted by Cam W. on March 15, 2003, at 22:03:39
how are you doing?* hugs to you* I hope I didn't offend you-it was probably me and a bad mood.
sorry
Posted by Cam W. on March 18, 2003, at 19:35:25
In reply to Re: Seroquel is not an SSRI. Gee, thanks alot! ;^P » Cam W., posted by KrissyP on March 18, 2003, at 12:28:27
Krissy - No, I'm not upset at all. If you notice, the smiling man is winking (at the end of the header).
- Cam
Posted by Krissy P on March 19, 2003, at 0:41:21
In reply to Re: Seroquel is not an SSRI. Gee, thanks alot! ;^P » KrissyP, posted by Cam W. on March 18, 2003, at 19:35:25
lol-yeah, winkin with the big nose-:-)LOL I know you weren't upset.
I'm a sensitive girl-workin on it though;)
Take care:-)
> Krissy - No, I'm not upset at all. If you notice, the smiling man is winking (at the end of the header).
>
> - Cam
This is the end of the thread.
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