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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Bob on April 21, 2002, at 17:34:53
Does anybody know anything about the possible development of an "XR" for of Neurontin? It seems that drug would enhanced greatly by a slow release formula. I've looked on the internet, and cannot seem to find any evidence of it in the works.
Bob
Posted by Ritch on April 21, 2002, at 22:14:52
In reply to Extended Release Neurontin, posted by Bob on April 21, 2002, at 17:34:53
> Does anybody know anything about the possible development of an "XR" for of Neurontin? It seems that drug would enhanced greatly by a slow release formula. I've looked on the internet, and cannot seem to find any evidence of it in the works.
>
> BobBob,
They would be interested in it if it wasn't for their development of a more refined pregabalin. Perhaps when that gains market approval-then we might see a "XR" version of that.
Mitch
Posted by Bob on April 22, 2002, at 1:13:56
In reply to Re: Extended Release Neurontin » Bob, posted by Ritch on April 21, 2002, at 22:14:52
So, they've basically orphaned Neurontin already? When is Pregabalin due out, and is its half-life any better? When you say "more refined", what exactly do you mean?
Bob
> Bob,
>
> They would be interested in it if it wasn't for their development of a more refined pregabalin. Perhaps when that gains market approval-then we might see a "XR" version of that.
>
>
> Mitch
Posted by Ritch on April 22, 2002, at 10:39:03
In reply to Re: Extended Release Neurontin » Ritch, posted by Bob on April 22, 2002, at 1:13:56
Hi Bob,
I believe the patent on Neurontin (gabapentin) is about to run out-I think sometime this year or early next year. Anyhow, the "refined" statement was taken from a press release about a pregabalin clinical trial-I think the term I remember was "refined molecule". Also, from what I remember it has about roughly double the potency (milligram wise)to achieve similar clinical effects. I don't recall anything about its half-life, however. It would be nice if it was more like 8-12 hrs. instead of 5-7hrs. !
Mitch
> So, they've basically orphaned Neurontin already? When is Pregabalin due out, and is its half-life any better? When you say "more refined", what exactly do you mean?
>
> Bob
>
>
>
> > Bob,
> >
> > They would be interested in it if it wasn't for their development of a more refined pregabalin. Perhaps when that gains market approval-then we might see a "XR" version of that.
> >
> >
> > Mitch
Posted by Bob on April 22, 2002, at 13:26:33
In reply to Re: Extended Release Neurontin » Bob, posted by Ritch on April 22, 2002, at 10:39:03
This is the end of the thread.
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