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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by johnj on April 2, 2002, at 11:07:18
Dr. Kramer,
Have you ever heard of an increase in side effects or depressive sysmptoms after excercising? I had done well on pamelor for over 9 years and was doing well until I started to jog. I thought excercise was supposed to aid in recovery. Previously, I had done ok when excercsing but after a bout of pneumonia excercising seemed to negatively affect my sleep. Can antibiotics mess with the AD's? It has been a struggle for the last several months. Weightlifting does not have the negative mood affect as aerobic excercising either. Remeron was great at first, but the fogginess is too hard to handle. Thank you
John
Posted by Dr. Kramer on April 2, 2002, at 20:04:37
In reply to Kramer: meds and excercise, posted by johnj on April 2, 2002, at 11:07:18
My guess is that the issue is dehydration. Pamelor (nortriptyline) causes orthostatic hypotension (you get dizzy if you stand up too fast) which is made worse by dehydration. Try drinking lots of water before, during and after jogging and see if that helps. Antibiotics usually don't bother AD's much.
Posted by colin wallace on April 3, 2002, at 12:37:21
In reply to Kramer: meds and excercise, posted by johnj on April 2, 2002, at 11:07:18
John,
I experienced exactly the same thing, namely an increase in depressive symptoms after (aerobic) exercise, and whilst taking amitriptyline (Pamelor's 'Mother-drug').I never experienced this (pretty awful) post-exercise worsening on any other AD.(although some would make me feel off colour during exercise).
Looked into this myself, and can't really explain it at all.
Posted by johnj on April 4, 2002, at 10:41:46
In reply to Re: meds and excercise--- Johnj, posted by colin wallace on April 3, 2002, at 12:37:21
Did you switch to another AD? and if yes, how did you do it and what did you switch too? I have started remeron, and the spacey side effects are just too much. I was at 30mg went to 37.5 then to 45 and it just got worse. I am down to 22.5 mg and the spacey feeling is better, but the tiredness is horrible. I have trouble sleeping so I will miss that part about remeron. I didn't experience the reduction in side effects as I raised the dose like others have mentioned. I am thinking about trying some SAM-e, but am not sure if it is something I should try or not. Thanks and take care.
John
Posted by Ron Hill on April 8, 2002, at 18:02:11
In reply to Question for Colin, posted by johnj on April 4, 2002, at 10:41:46
> Did you switch to another AD? and if yes, how did you do it and what did you switch too? I have started remeron, and the spacey side effects are just too much. I was at 30mg went to 37.5 then to 45 and it just got worse. I am down to 22.5 mg and the spacey feeling is better, but the tiredness is horrible. I have trouble sleeping so I will miss that part about remeron. I didn't experience the reduction in side effects as I raised the dose like others have mentioned. I am thinking about trying some SAM-e, but am not sure if it is something I should try or not. Thanks and take care.
> John
-------------------John,
As I mentioned in another thread, Colin is unavailable for one week. I am posting so that this thread will appear on the current page of the board and, thereby, increase the probability of Colin seeing it (through his prison bars) and responding to it once he has completed his debt to society.
-- Ron
Posted by colin wallace on April 23, 2002, at 11:11:10
In reply to Question for Colin, posted by johnj on April 4, 2002, at 10:41:46
Hi John,
it's strange, but those two particular meds. (amitriptyline-nortriptyline's metabolite- and remeron caused exactly the same effects in me as you describe, post aerobic exercise.For me personally, any percieved benefits of these meds was wholly negated by the completely poleaxed feeling I'd get following running or cycling.It was pretty awful, prevented me from functioning at all, and lasted ages.
As for the reasons behind it, ican only guess that it must have something to do with the sedating nature of both these AD's- I never experienced post exercise probs with, say lofepramine/imipramine.
If you plan to discontinue Remeron, then I would just try an immediate switch to be honest.Your dose is low, and you don't seem to have been on it for too long.Generally, Remeron is not known to cause many discontinuation probs- I got none whatsoever, and I'd been up to 90mg at one point.
You could though try splitting a 15 mg pill for a few weeks at night, taking 7.5mg, whilst introducing Sam-e first thing in the morning.It should quickly improve your energy-levels/alertness, at the very least.You may not then need to ditch the low-dose Remeron if it helps you sleep.
I guarantee you'll have no problems running etc on Sam-e.Whether it will work for your depression of course, is another matter.Fingers crossed.It works fantastically for me, and my depression was severe.Col.
This is the end of the thread.
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