Psycho-Babble Medication Thread 86295

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Paxil and liver enzymes (ALAT ASAT)

Posted by ben on December 8, 2001, at 9:04:18

I take Paxil for about 5 months 30 mg/day and developed a non-viral hepatitis (increase of the liver enzymes called transaminases ALAT and ASAT). Could it be the paxil ? My liver was allways in a good condition under several other ADs.

 

Re: -- SSRI and liver damage ?! » ben

Posted by IsoM on December 12, 2001, at 15:54:08

In reply to Re: -- SSRI and liver damage ?!, posted by ben on December 9, 2001, at 1:16:52

Ben, all SSRIs can cause elevated liver enzymes levels & just because previous ones haven't doesn't mean a new one wouldn't. What it does mean is that Paxil may be one that does affect your liver.

If the liver is unable to properly break down the drug into its metabolites, it can end up damaging the individual liver cells causing the increase in enzyme levels.

Has anything else changed in your environment or diet that might be the casue or contribute to the higher levels? Many, many different chemicals & drugs can affect the liver - acetaminophen (Tylenol) is one of the worse. Personally, I increased my vitamin C intake with a time-release supplement. Also one of the professors at my college said that many people don't realise that they need to increase their water intake when taking meds & not just for their kidneys.

I'd suggest stopping the Paxil & trying a different one. Make sure your liver is checked through the change too.

> > I take Paxil for about 5 months 30 mg/day and developed a non-viral hepatitis (increase of the liver enzymes called transaminases ALAT and ASAT). Could it be the paxil ? My liver was allways in a good condition under several other ADs.
>
> Please read my thread and talk about your expieriences.


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