![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by N on July 21, 2001, at 17:54:21
I am currently on Wellbutrin -- 450 mg/day but working my way up to 600 mg/day. Would it be wise to go on a low carb diet (not too low carb, I just have practically been surviving on bread and I was thinking of cutting it out)? My concern is whether or not the change to a lower carb diet would in some way increase my body's response to the Wellbutrin, putting me at a higher risk for seizures.
Posted by sl on July 21, 2001, at 18:48:15
In reply to wellbutrin dosage and low carb diet, posted by N on July 21, 2001, at 17:54:21
I doubt it. 600mg is a LOT of wellbutrin, I hope you know that.You might start by just making sure you're eating good heavy multi-grain bread. I was on a low-carb diet, though, and it didn't hurt me at all. :)
sl
> I am currently on Wellbutrin -- 450 mg/day but working my way up to 600 mg/day. Would it be wise to go on a low carb diet (not too low carb, I just have practically been surviving on bread and I was thinking of cutting it out)? My concern is whether or not the change to a lower carb diet would in some way increase my body's response to the Wellbutrin, putting me at a higher risk for seizures.
Posted by SalArmy4me on July 21, 2001, at 20:23:43
In reply to wellbutrin dosage and low carb diet, posted by N on July 21, 2001, at 17:54:21
Did your doctor say you could take 600 mg/day? After 450 mg, the Wellbutrin dose-response curve flattens and no more gains can be made at even higher doses.
Plus: "This antidepressant has a narrow therapeutic index in terms of the dose needed for antidepressant efficacy versus the dose that causes seizures.57 The minimum recommended dose for antidepressant response is 300 mg/day and a number of patients will need the maximum recommended dose of 450 mg/day. At doses of 450 mg/day or less, the seizure risk is 0.4%. Increasing the dose to 600 mg/day causes a five-fold increase in the seizure risk..."
http://www.preskorn.com/cgi-bin/sp.pl?words=buproprion&wt=be&bl=an&d=/books/omd_s8.html
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.