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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by natg on January 12, 2001, at 19:52:37
Hello,
Can anybody help me? When I started Mirapex I had nausea but it subsided. I've increased my dose recently and the nausea has come back. I've also decided to cut back on Risperdal to see whether I need it. It's hard to know which med is working.
The nausea is really bothering me, anybody have any suggestions????Best of Health to all,
Nat
Posted by SLS on January 12, 2001, at 20:20:25
In reply to Mirapex and nausea, PLEASE SOME HELP!, posted by natg on January 12, 2001, at 19:52:37
> Hello,
> Can anybody help me? When I started Mirapex I had nausea but it subsided. I've increased my dose recently and the nausea has come back. I've also decided to cut back on Risperdal to see whether I need it. It's hard to know which med is working.
> The nausea is really bothering me, anybody have any suggestions????
>
> Best of Health to all,
> Nat
Hi Nat.Opinion only...
Maintain your dosage of Risperdal until you settle on the dosage of Mirapex that you consider optimal. The Risperdal may have left the system more sensitive to Mirapex and the nausea it causes, so keep taking the Risperdal to keep things in balance while you are titrating the Mirapex. Hopefully, the system will accomodate itself to the Mirapex and the nausea will subside. Allow the system to reach an equilibrium before doing anything with the Risperdal. If you feel great, then don't try to fix what might not be broken right away. Perhaps you can wait a month from the time you settle on your Mirapex dosage to attempt to withdraw Risperdal. Obviously, you won't know what is doing what if you change both at the same time.
Logic is simple. Following logic is difficult.
I'll let someone else comment on whether or not ondansetron can be used to offset Mirapex-induced nausea.
- Scott
Posted by JahL on January 12, 2001, at 20:21:26
In reply to Mirapex and nausea, PLEASE SOME HELP!, posted by natg on January 12, 2001, at 19:52:37
> When I started Mirapex I had nausea but it subsided. I've increased my dose recently and the nausea has come back.
Starting Mirapex caused nausea but you said it sudsided with time. Could this latest bout of nausea be transient too & just related to the sudden dose increase?
> I've also decided to cut back on Risperdal to see whether I need it. It's hard to know which med is working.
> NatTry to maintain a constant. EITHER cut back on Risperdal OR increase Mirapex. That way you can isolate which drug is doing what. How about keeping Mirapex @ pre-nausea levels whilst slowly eliminating Risperdal (which you said pooped-out)?
If the anti-depressant effect is maintained then you could try slowly titrating the Mirapex upwards to see if any further benefit can be gained. I've seen a study in which depressed patients responded significantly more to 5mg/day than 1mg/day (though admittedly with a few more adverse reactions).
Again, just some thoughts; good luck,
Jah.
Posted by JahL on January 12, 2001, at 20:27:42
In reply to Re: Mirapex and nausea, PLEASE SOME HELP! » natg, posted by SLS on January 12, 2001, at 20:20:25
> > Hello,
> > Can anybody help me? When I started Mirapex I had nausea but it subsided. I've increased my dose recently and the nausea has come back. I've also decided to cut back on Risperdal to see whether I need it. It's hard to know which med is working.
> > The nausea is really bothering me, anybody have any suggestions????
> >
> > Best of Health to all,
> > Nat
>
>
> Hi Nat.
>
> Opinion only...
>
> Maintain your dosage of Risperdal until you settle on the dosage of Mirapex that you consider optimal. The Risperdal may have left the system more sensitive to Mirapex and the nausea it causes, so keep taking the Risperdal to keep things in balance while you are titrating the Mirapex. Hopefully, the system will accomodate itself to the Mirapex and the nausea will subside. Allow the system to reach an equilibrium before doing anything with the Risperdal. If you feel great, then don't try to fix what might not be broken right away. Perhaps you can wait a month from the time you settle on your Mirapex dosage to attempt to withdraw Risperdal. Obviously, you won't know what is doing what if you change both at the same time.
>
> Logic is simple. Following logic is difficult.
>
> I'll let someone else comment on whether or not ondansetron can be used to offset Mirapex-induced nausea.
>
>
> - ScottScott, what I was trying 2 say. Must've just beaten me to posting!
Jah.
Posted by AndrewB on January 15, 2001, at 11:27:54
In reply to Re: Mirapex and nausea, PLEASE SOME HELP!, posted by JahL on January 12, 2001, at 20:27:42
NatG,
I found Mirapex to give me nausea with each increase in dose but for it to rapidly subside.
Also, Domperidone is supposed to be effective for dealing with the nausea. It works by blocking the peripheral dopamine receptors. It is available in Europe but not the US.
AndrewB
This is the end of the thread.
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