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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by anita on May 30, 2000, at 20:40:24
For those of you who have tried both reboxetine and Wellbutrin, can you tell me what the main differences are between them in terms of how they made you feel, both when first starting them and then after 4-8 weeks? I didn't do well on Wellbutrin (irritability, anxiety) and I'm wondering if I should bother trying reboxetine.
Thanks,
anita
Posted by AndrewB on May 30, 2000, at 22:37:18
In reply to Reboxetine vs. Wellbutrin, posted by anita on May 30, 2000, at 20:40:24
Anita,
Start reboxetine at 4 mgs. for 12 days. If side effects are only minor, go to 8 mgs. This is the standard dosage. After 3 weeks at 8 mgs, dosage may be increased to 10 mgs. if needed. Do not exceed 12 mgs. If you encounter significant side effects at 4 or 10 mgs., cut dosage in half, and remain at the lower dcosage until you are nearly side effect free and go up gradually. If agitation is a problem, SSRis can be combined with reboxetine.
I took wellbutrin for 8 weeks. Nice energy at first but after 4 weeks anxiety and agitation built up. I now take reboxetine and experience no increased anxiety or agitation. Your experience of course may be different.
If you do decide to take rebox., with a prescript. it may be purchased at half price from Farmacia Cerati (www.farmaciacerati.com). Super service!
Posted by CarolAnn on May 31, 2000, at 9:07:55
In reply to Re: Reboxetine vs. Wellbutrin, posted by AndrewB on May 30, 2000, at 22:37:18
Hey Andrew, I had no energy boost from Wellbutrin at all. How does Reboxetine do 'energywise'? Smiles! CarolAnn
Posted by AndrewB on May 31, 2000, at 13:36:41
In reply to Re: Reboxetine vs. Wellbutrin- ? for AndrewB, posted by CarolAnn on May 31, 2000, at 9:07:55
Reboxtine normally gives a person the energy to do stuff without the feeling of being overstimualted. If you did not get any energy boost from Wellbutrin, it does not bode well for you getting a boost from reboxetine.
Let me ask you. Did you get an intial energy boost from Wellbutrin that went away or did you not respond at all. Let me know.
Both Wellbutrin and Reboxetine give one a sense of energy via NE activation.
There are some quick acting NE drugs that may give you a better idea of whether NE is involved in your fatigue. Try ephedrine or something that has ephedrine in it like a Metabolife energy bar. If it takes away fatigue, it probably indicates you can find an NE drug to help take away your fatigue over the long term. I've read that 1000mg. of tyrosine combined with B6 can also be used to determine if fatigue is NE caused.
Posted by anita on May 31, 2000, at 22:37:49
In reply to Re: Reboxetine vs. Wellbutrin, posted by AndrewB on May 30, 2000, at 22:37:18
Andrew,
Thanks very much for the info. I'm going to order it from Farmaciera Certati today. I will be taking it with Zoloft, so hopefully that will keep the anxiety to a minimum.
BTW, I just read a study that said that the optimal dose of Mirapex (alone) as an AD is 5mg -- did you go high enough? Pretty pricey, tho.
anita
> Anita,
>
> Start reboxetine at 4 mgs. for 12 days. If side effects are only minor, go to 8 mgs. This is the standard dosage. After 3 weeks at 8 mgs, dosage may be increased to 10 mgs. if needed. Do not exceed 12 mgs. If you encounter significant side effects at 4 or 10 mgs., cut dosage in half, and remain at the lower dcosage until you are nearly side effect free and go up gradually. If agitation is a problem, SSRis can be combined with reboxetine.
>
> I took wellbutrin for 8 weeks. Nice energy at first but after 4 weeks anxiety and agitation built up. I now take reboxetine and experience no increased anxiety or agitation. Your experience of course may be different.
>
> If you do decide to take rebox., with a prescript. it may be purchased at half price from Farmacia Cerati (www.farmaciacerati.com). Super service!
Posted by AndrewB on June 1, 2000, at 1:48:15
In reply to Re: Rebox vs. Well -- to Andrew!, posted by anita on May 31, 2000, at 22:37:49
Anita,
You wouldn't be able to guide me to the source of that Mirapex study would you? I was taking 1 mg.
Best wishes with the reboxetine.
Posted by CarolAnn on June 1, 2000, at 8:31:24
In reply to Re: Reboxetine vs. Wellbutrin- ? for AndrewB, posted by AndrewB on May 31, 2000, at 13:36:41
> Let me ask you. Did you get an intial energy boost from Wellbutrin that went away or did you not respond at all. Let me know.
>
Andrew, I had no "energy" response at all to Wellbutrin. I've heard about those Metabolife bars from someone else here(JohnL, I think). I will definitely try your suggestion.
So far, the only thing that has helped increase my energy is Adderall, unfortunately, the longer I use it, the less helpful it is, even when I take a break from it for a couple weeks, it just doesn't come back to the way I felt when I first started taking it. Thank you for replying! CarolAnn
Posted by robert on June 1, 2000, at 11:38:00
In reply to Re: Reboxetine vs. Wellbutrin- ? for AndrewB, posted by CarolAnn on June 1, 2000, at 8:31:24
Andrew
Have you had any sexual side affects with roboxetine? Any other side affects
Robert
Posted by AndrewB on June 1, 2000, at 12:13:51
In reply to Re: Reboxetine vs. Wellbutrin- ? for AndrewB, posted by CarolAnn on June 1, 2000, at 8:31:24
Carol Ann,
Let me know how it goes with the ephedrine. If it does something for your then some regimen of some NE drug can be found to help you. If not, there are other stratagies to deal with fatigue. This is a process of discovery, be patient.
AndrewB
Posted by AndrewB on June 1, 2000, at 12:21:37
In reply to Re: Reboxetine vs. Wellbutrin- ? for AndrewB, posted by robert on June 1, 2000, at 11:38:00
> Andrew
>
> Have you had any sexual side affects with roboxetine? Any other side affects
>
> RobertYes, I have had sexual side effects. Others have too. I think they are fairly common with men. Rebox. causes softer erections and retrograde ejaculations. There are ways to deal with this however if you are still interested in this medicine. Rebox's other side effects are usually transitory.
Posted by anita on June 2, 2000, at 16:06:35
In reply to Re: Rebox vs. Well -- to Anita!, posted by AndrewB on June 1, 2000, at 1:48:15
Andrew,
You can find two new studies on pramipexole as an antidepressant on Medline (just enter "pramipexole" and the articles are among the first 5 or so listed). One study said that 1mg to 5mg of pramipexole alone was as effective as prozac 20-40mg and worked more quickly, tho it noted that the most improvement was seen in those taking as much as 5mg a day.
The second study, of one person, said that 100mg Zoloft + 1mg pramipexole alleviated a treatment-resistant patient's depression.
anita
> Anita,
>
> You wouldn't be able to guide me to the source of that Mirapex study would you? I was taking 1 mg.
>
> Best wishes with the reboxetine.
This is the end of the thread.
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