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Dr. Bob is Robert Hsiung, MD,
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Posted by Lamdage22 on January 21, 2015, at 10:40:05
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by ed_uk2010 on January 21, 2015, at 6:57:55
Havent changed my other meds. 100mg of amisulpride and i feel like sh*t.
I havent been very motivated before but now?? Terrible
Posted by ed_uk2010 on January 21, 2015, at 10:59:15
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by Lamdage22 on January 21, 2015, at 10:40:05
> Havent changed my other meds. 100mg of amisulpride and i feel like sh*t.
>
> I havent been very motivated before but now?? TerribleSo you were more motivated on 50mg and less on 100mg?
To be honest, you're on three antipsychotics. You may not be able to tolerate amisulpride without reducing Zyprexa.
Posted by Lamdage22 on January 21, 2015, at 11:39:11
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by ed_uk2010 on January 21, 2015, at 10:59:15
Initially i thought it was mood lifting.
Posted by ed_uk2010 on January 21, 2015, at 13:17:33
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by Lamdage22 on January 21, 2015, at 11:39:11
>Initially i thought it was mood lifting.
You're taking three D2 antagonists now. I don't think the mood elevation will reappear unless you reduce something. Too much D2 antagonism is usually unpleasant.
Has your doctor suggested how to reduce?
Posted by Lamdage22 on January 23, 2015, at 7:47:40
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by ed_uk2010 on January 21, 2015, at 13:17:33
We have quit the project now.
I could not do therapy which is very important for the institution im in.
I will see that i take as little of zyprexa as possible.
Which for now means 12.5 mg
Posted by ed_uk2010 on January 23, 2015, at 11:13:28
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by Lamdage22 on January 23, 2015, at 7:47:40
Shame it didn't work out.
So... do you need to be on such a high dose of Seroquel as well as Zyprexa? Is that important for stability?
Posted by Lamdage22 on January 25, 2015, at 11:01:13
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by ed_uk2010 on January 23, 2015, at 11:13:28
If i take less i cant sleep!
And if i take much less i indulge in psychotic thought.
I will ask my PD tomorrow if i can get something for sleep that is non-addictive and non diabetes forming.
Posted by ed_uk2010 on January 25, 2015, at 11:05:38
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 11:01:13
> If i take less i cant sleep!
>
> And if i take much less i indulge in psychotic thought.
>
> I will ask my PD tomorrow if i can get something for sleep that is non-addictive and non diabetes forming.How do you take the 900mg? I mean, how do you divide it across the day?
Posted by Lamdage22 on January 25, 2015, at 12:00:50
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by ed_uk2010 on January 25, 2015, at 11:05:38
During the day: Seroquel prolong: 100- 0 - 300
At night : Seroquel 500
Posted by ed_uk2010 on January 25, 2015, at 12:10:54
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 12:00:50
> During the day: Seroquel prolong: 100- 0 - 300
> At night : Seroquel 500>Seroquel 900mg
Zyprexa 10mg
Lithium orotate 480mg
Metformin 1500mg
Effexor 20mgSo, is this list still correct? Are you diabetic or are you on metformin to help with weight gain on the antipsychotics?
Posted by Lamdage22 on January 25, 2015, at 12:25:07
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by ed_uk2010 on January 25, 2015, at 12:10:54
Zyprexa 15.
Metformin for weight gain!
Posted by Lamdage22 on January 25, 2015, at 12:40:20
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 12:25:07
There you go.
Posted by ed_uk2010 on January 25, 2015, at 13:16:25
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 12:40:20
> There you go.
Thanks, so, how overweight are you and has metformin helped?
Posted by Lamdage22 on January 25, 2015, at 13:25:23
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by ed_uk2010 on January 25, 2015, at 13:16:25
Maybe 20-30 pounds.
Yes it helped tremendously.
I wonder if i can lower my diabetes risk by going on, say 1500mg of Seroquel and ditching the Typrexa.
Posted by ed_uk2010 on January 25, 2015, at 13:31:14
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 13:25:23
>I wonder if i can lower my diabetes risk by going on, say 1500mg of Seroquel and ditching the Zyprexa.
I don't think there's any evidence that that would be safe or effective. Very high doses of Seroquel are occasionally tried, but they don't generally seem to be better than standard doses.
What happens if you reduce Zyprexa slowly while staying on Seroquel 900mg?
Posted by Lamdage22 on January 25, 2015, at 13:33:03
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 13:25:23
Doctors do this sometimes.
1800 even.
Posted by Lamdage22 on January 25, 2015, at 13:34:07
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by ed_uk2010 on January 25, 2015, at 13:31:14
Then i usually cant sleep with 12.5 mg Zyprexa so i go and get another 2.5
....
Posted by Lamdage22 on January 25, 2015, at 13:37:48
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 13:34:07
I will talk to my doctor about the diabetes risk, the not falling asleep and all that. He wont like to hear my concerns.. He is in love with his AP meds.
I could get a low potency sedating AP for sleep or whatever.
Or trazodone. IDK.
Just something that doesnt pose a risk like Zyprexa.
Posted by Lamdage22 on January 25, 2015, at 13:41:06
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 13:37:48
perhaps taking the seroquel all at night will knock me out.
Posted by ed_uk2010 on January 25, 2015, at 13:51:35
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 13:41:06
>perhaps taking the seroquel all at night will knock me out.
You could consider taking more at night and less during the day assuming that your blood pressure and pulse are OK (both sitting and standing). I don't think it would be a good idea to try it unless you've had these tests. Several measurements should be taken on a few different occasions.
Do you know what your BP and pulse are, taken sitting and shortly (a couple of mins) after standing up?
Also, I think you would need to gradually reduce your daytime dose by 100mg and increase your night time dose by 100mg in several steps.
Posted by Lamdage22 on January 25, 2015, at 13:54:10
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by ed_uk2010 on January 25, 2015, at 13:51:35
Ed, no i dont know.
I used to get dizzy upon standing up from lying but i dont anymore.
I will take this into consideration.
Posted by ed_uk2010 on January 25, 2015, at 14:08:24
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 13:54:10
>I used to get dizzy upon standing up from lying but i dont anymore.
That's a good sign. Be careful of the dizziness returning if you take more in one dose. The risk is fainting and falling. So, do it in stages if you do do it.
Posted by Lamdage22 on January 25, 2015, at 14:24:37
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by ed_uk2010 on January 25, 2015, at 14:08:24
Okay. Thanks. Ed-
Posted by Lamdage22 on January 26, 2015, at 5:22:25
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 25, 2015, at 14:24:37
My doctor prescribed a low potency sedating antipsychotic called pipamperone for sleep and further he suggested valproic acid for my depression.
Posted by ed_uk2010 on January 26, 2015, at 9:21:00
In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 26, 2015, at 5:22:25
> My doctor prescribed a low potency sedating antipsychotic called pipamperone for sleep and further he suggested valproic acid for my depression.
Your doctor certainly likes antipsychotics!
You're already on a low potency sedating antipsychotic: Seroquel - and lots of it, as well as Zyprexa. It is an unusual choice to add a third antipsychotic for sleep in someone already on two antipsychotics. What's his logic?
So, how bad is your depression right now? And how bad is your insomnia (when not attempting to reduce Zyprexa)? Are you hearing any voices, experiencing any paranoia or suffering any other psychosis-like symptoms?
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