Psycho-Babble Medication Thread 661128

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Re: Who's Still Going Strong with EMSAM?

Posted by pulse on June 29, 2006, at 9:52:46

In reply to Re: Who's Still Going Strong with EMSAM?, posted by ZeitGuest on June 29, 2006, at 1:10:24

according to substance abuse 'expert's and pdocs supposedly well versed in - who all suggest wellbutrin - ha!, it makes no sense re: my fairly long past history of cocaine use, BUT i'm now 100% SURE that dopamine in maois & i are done.

in tcas, *if i could still tolerate,* dopamine's GOT to be much more balanced w/ serotonin & norepinephrine (other than desipramine).

emsam somehow hits dopamine hard from outset. for only a VERY small minority of those posting here, you can easily see this by the side-effects they encountered, and that most are still struggling with at 4- 6 wks. or longer.

emsam (even moreso parnate) for me = speed, plain & simple. unlike perhaps (???) the majority of street-drug stimulant users, i hated speed - 2 times 30 yrs ago + ritalin trial of 2 mos., 3 yrs. ago, that i (not pdoc) stopped.

dopamine in maois - for me - case closed.

if all i want is a blast of speed, i'll just whip out a patch & put on for 1/2 hr. TOPS. would that be considered a relapse? kidding...or maybe...not.

pulse

 

Re: Who's Still Going Strong with EMSAM? Pulse

Posted by cecilia on June 29, 2006, at 18:03:30

In reply to Re: Who's Still Going Strong with EMSAM?, posted by pulse on June 29, 2006, at 0:58:31

Pulse, sorry this didn't work out for you even at the low doses. All the MAOI's definitely build up gradually in your system, that definitely was my experience with Nardil, no side effects whatsoever for 38 days (28 at 45 mg, 10 at 60) then boom hit like a ton of bricks and not with anything good. But I think the patch may actually make this building up problem even worse, obviously a lot more research needs to be done. My eye problems are finally starting to improve, my eye doctor (not the idiot who wanted to do surgery for dry eyes, another one) said I had a dermatitis on my eyelids, he said it could well be a reaction to the Emsam, though the idiot doctor who was ready to operate, sight unseen, said that Selegiline didn't cause dry eyes, should actually help them! For any one else who gets the same problem, TobraDex ointment on the eyelids (and/or getting the poisonous Emsam out of my system), was what finally helped, my eyes are still sore and itchy but improved. This sounds trivial but it was EXTREMELY painful, and of course the Emsam insomnia didn't exactly help the situation. Cecilia

 

Re: Who's Still Going Strong with EMSAM? Pulse

Posted by Last Chance on June 29, 2006, at 19:03:36

In reply to Re: Who's Still Going Strong with EMSAM? Pulse, posted by cecilia on June 29, 2006, at 18:03:30

One month total now on Emsam - 8 days on 9mg 24/7. Yesterday my depression, and still today, is as bad as before I started. Agitated depression. I don't really know what to do - sleeping ok, not great. Definitely have no more of that energy that I was getting for awhile. Even having extra trouble thinking and making this post. I know I need to try this higher dose for a longer time, but am having thoughts of quitting. I don't get it - any thoughts out there about this? Thanx, Richard

 

Re: Who's Still Going Strong with EMSAM? » jealibeanz

Posted by SFY on June 29, 2006, at 23:10:08

In reply to Re: Who's Still Going Strong with EMSAM?, posted by jealibeanz on June 28, 2006, at 16:53:37

> Oops...by SAD I meant seasonal affective disorder ("winter depression"). Does it help with this? However, I do have social anxiety as well.

Sorry, I actually thought that for a second - ever since they changed Social Phobia to Social Anxiety Disorder it's been a source of confusion.

I haven't looked into it so I can't say whether MAOI's have been studied for treating SAD - though I don't know that that's a class of meds you want to start up for a few months out of the year.

 

Re: Who's Still Going Strong with EMSAM? Pulse » cecilia

Posted by pulse on June 30, 2006, at 1:18:50

In reply to Re: Who's Still Going Strong with EMSAM? Pulse, posted by cecilia on June 29, 2006, at 18:03:30

thanks so very much for your empathy, cecilia.

< But I think the patch may actually make this building up problem even worse, obviously a lot more research needs to be done. >

you could very well also be right re: all your above. what do any of us REALLY know about emsam?

one would (like to) think that the 18-20 yrs. of research already done on it, would surely be enough, but in my view, as yours, it most definitely is NOT!

i can easily believe your eye problem was dermatological in nature. all times i was on emsam, i noticed that all my skin had become FAR dryer than from any ad, ever before (my skin is normally still on the slightly oily side.) my wrists to elbows became reddish; itchiness was starting. i had only a slight problem at the application sites, though.

woo - glad for you that no operation was performed!

pulse

 

Re: Who's Still Going Strong with EMSAM? Pulse » Last Chance

Posted by pulse on June 30, 2006, at 1:31:31

In reply to Re: Who's Still Going Strong with EMSAM? Pulse, posted by Last Chance on June 29, 2006, at 19:03:36

hi Richard,

my only input is that emsam (to say the least) is a highly unpredictable drug. only you can make the choice, but - me - i would not go further at the higher dosge. i would quit.

i also had that extra trouble thinking, much less posting. people had no idea how much time i had to spend to edit, then re-edit - ad nauseum...every single post.

best of luck with whatever YOU decide.

pulse

p.s i must be honest: i think we'll find that, for vast majority, emsam - as a last hope - won't materialize. there's something quite amiss (or missing) with it.

 

Re: Who's Still Going Strong with EMSAM? Pulse

Posted by jealibeanz on June 30, 2006, at 4:38:12

In reply to Re: Who's Still Going Strong with EMSAM? Pulse » Last Chance, posted by pulse on June 30, 2006, at 1:31:31

You think so? I wonder how the drug companies can be thaaaat far off with a medication that's already in use. Maybe the majority of people using aren't expriencing these effects, but it's the people here who are reporting them. Just a thought/hope.

 

Re: Who's Still Going Strong with EMSAM? Pulse » jealibeanz

Posted by pulse on June 30, 2006, at 12:12:23

In reply to Re: Who's Still Going Strong with EMSAM? Pulse, posted by jealibeanz on June 30, 2006, at 4:38:12

no, i KNOW they're thaaaat far off and for far too many reasons to take up space here, but here is one: i talked 3 times to one of somerset's head emsam researchers....& was outright lied to.

i know your dream is emsam, as was mine. i mentally and physically exhausted myself far more than should be required of ANYONE, JUST to tolerate this drug.

your posts are often not clear: as in, < a medication that's already in use. >

i will now mind-read & (be forced to) assume that you must mean oral selegiline, as emsam's only been in use for a very few people before april 15, 2006; then only by 2 - 4 days before. btw, i was one of these very few. for all others, as of today, that then would = approx. 2 months + 2 weeks.

re: oral selegiline, i have no personal experience, but from reading here and elsewhere, seems there are few for whom it works well. has many horrid SEs, and often requires very high dosing. of course, there are folks who are exceptions to this.

you're correct that - usually - those doing well would not be posting as much, here or anywhere; maybe not posting at all (pity!), but re: emsam all here have REALLY gone to the mat, and, again - the vast majority have still had little to no success, or are even getting worse.

i realize you're suffering, and looking for answers, but from the sheer number of your posts, i would suggest that therapy may well be your best bet. i know you have some privacy concerns, re: stigma, but if your records were even able to be accessed, therapy would be far less 'stigmatizing' than psych med/s. (not that any stigma should exist anywhere in 2006!, no matter what field anyone hopes to be in or is in.)

pulse

 

Re: Who's Still Going Strong with EMSAM?

Posted by helpme on June 30, 2006, at 12:48:48

In reply to Re: Who's Still Going Strong with EMSAM? Pulse » jealibeanz, posted by pulse on June 30, 2006, at 12:12:23

I've been on EMSAM since the week it came out, and my conclusion is that it is $475. glorified scotch tape. I often can't even get it to stick on properly- we are supposed to exercise to relieve depression, right? The patch usually partially sweats or wrinkles off, even off my thigh. For me, it has been a major let down, and I'm crushed because I had such high hopes. Nothing has been working for me, except exessive doses of stimulants (ie 60- 80mg ritalin)- which doctor is reluctant to prescribe at amounts adqeuate for me to perceive and pharmacists make me feel like a drug addict. Is it possible I have a weird drug metabolism?

 

Re: Who's Still Going Strong with EMSAM? Pulse

Posted by jealibeanz on June 30, 2006, at 12:54:24

In reply to Re: Who's Still Going Strong with EMSAM? Pulse » jealibeanz, posted by pulse on June 30, 2006, at 12:12:23

Yes, I meant oral selegiline. I suppose I was just fixated on EMSAM since it's new and different from anything I've tried. I don't think EMSAM or any other medication from another class is a horrible idea, it's worth a shot. I've been trying to get as many reviews about this particular medication so I can be informed. I'm not unrealistic and I also don't think there will ever be a miracle pill I'll take, but something to give me a slightly better quality of life.

 

Re: Who's Still Going Strong with EMSAM? Pulse

Posted by helpme on June 30, 2006, at 13:16:27

In reply to Re: Who's Still Going Strong with EMSAM? Pulse » Last Chance, posted by pulse on June 30, 2006, at 1:31:31


Seems that there are some serious product design problems with EMSAM. For starters- how about getting it so it actually sticks to skin that moves, wrinkles, and sweats? What did they do, test on immobile office workers in airconditioned locations?
No wonder it's unpredictable!


> hi Richard,
>
> my only input is that emsam (to say the least) is a highly unpredictable drug. only you can make the choice, but - me - i would not go further at the higher dosge. i would quit.
>
> i also had that extra trouble thinking, much less posting. people had no idea how much time i had to spend to edit, then re-edit - ad nauseum...every single post.
>
> best of luck with whatever YOU decide.
>
> pulse
>
> p.s i must be honest: i think we'll find that, for vast majority, emsam - as a last hope - won't materialize. there's something quite amiss (or missing) with it.
>
>

 

Re: Who's Still Going Strong with EMSAM? Pulse » helpme

Posted by SFY on June 30, 2006, at 14:42:58

In reply to Re: Who's Still Going Strong with EMSAM? Pulse, posted by helpme on June 30, 2006, at 13:16:27

>
> Seems that there are some serious product design problems with EMSAM. For starters- how about getting it so it actually sticks to skin that moves, wrinkles, and sweats? What did they do, test on immobile office workers in airconditioned locations?
> No wonder it's unpredictable!

Sounds like you might have gotten a bum batch of patches. Emsam stays on me in the gym (and I sweat buckets!) and in the shower afterwards.

 

Another Sticky Emsam Issue

Posted by SFY on June 30, 2006, at 14:48:25

In reply to Re: Who's Still Going Strong with EMSAM? Pulse, posted by helpme on June 30, 2006, at 13:16:27

Speaking of Emsam's sticking power, I do have one dilemma - namely, the need to rotate the location of the patch. Unfortunately, I have both an excess of body hair on my thighs and chest which preclude me from putting the patch on there. In addition, I have quite a bit of old scar tissue on my back which would likely be a barrier to the transdermal delivery system.

The best and most logical place for the patch is my upper arms which I can alternate from day to day. As I haven't had any rash or other skin reaction I don't see this as a problem but I'm wondering if anyone else sees any potential pitfalls in this approach?

 

Re: Who's Still Going Strong with EMSAM? Pulse

Posted by helpme on June 30, 2006, at 17:13:57

In reply to Re: Who's Still Going Strong with EMSAM? Pulse » helpme, posted by SFY on June 30, 2006, at 14:42:58

As for EMSAM not sticking,
I'm on my third box, so maybe it's just me. I don't have a lot of body hair.

 

Re: Who's Still Going Strong with EMSAM? Pulse » helpme

Posted by pulse on July 1, 2006, at 7:41:16

In reply to Re: Who's Still Going Strong with EMSAM? Pulse, posted by helpme on June 30, 2006, at 13:16:27

> Seems that there are some serious product design problems with EMSAM. For starters- how about getting it so it actually sticks to skin that moves, wrinkles, and sweats? What did they do, test on immobile office workers in airconditioned locations?
> No wonder it's unpredictable!

ty for the good laugh re: your other post: emsam = glorified scotch tape. yes, unpredictable in this way also, and, i'm sure, not just for you. no way!

not to mention the other infamous stick-ING wicket problem, otherwise known as fumble fingers. at the outrageous price, who wouldn't be nervous upon applying? how many patches or partials i'd lost, i have no clue.

however i DID belatedly learn a *possible* remedy:

just no longer giving a d*mn. then, they go on easily *almost* every time.

pulse

 

Re: Another Sticky Emsam Issue » SFY

Posted by pulse on July 1, 2006, at 7:51:16

In reply to Another Sticky Emsam Issue, posted by SFY on June 30, 2006, at 14:48:25

soon into my 1st of 4 (or was it 5? lol) failed trials, i put the patch or partial ONLY in the very same locations you are. i had next to no irritation at site, (BUT did have LOTS of redness, dryness + itching was starting on both of my wrists up to elbows).

i have no way of knowing if that would have increased substantially at site location itself -full patch/ 24 hrs - as it has for at least one other here.

pulse

 

Re: Another Sticky Emsam Issue

Posted by helpme on July 1, 2006, at 18:27:44

In reply to Re: Another Sticky Emsam Issue » SFY, posted by pulse on July 1, 2006, at 7:51:16

Thanks, Pulse. I think you have a point of "just slapping it on" being helpful. My doc gave me a sample box of 5 at first, and I swear I screwed up each one of those! Just think- a 15$ value apiece! I've gotten better, but the problem is still an issue, and sometimes i just can't figure out why. I'm usually having best luck on my thighs, so I alternate on them, but sometimes, no matter how secure the patch seems in the AM, by later in the day the edges are not quite on right anymore, or the patch is loose, or whatever. I wonder now, if uneven sticking could be a cause of so many of us having unsatisfactory or wildly different results from it? You know, if it is not firmly attached to skin, is medicine not absorbed completely? Of course I only apply on completely dry skin, no lotion- but that doesn't always matter.

Anyone else got tips for making the patch stick?

 

Pulse!!! Are you here??? » pulse

Posted by Donna Louise on July 1, 2006, at 22:30:02

In reply to Re: Another Sticky Emsam Issue » SFY, posted by pulse on July 1, 2006, at 7:51:16

I tried starting a new thread to get your attention but it didn't show up. This has happened to me before. I tried to babblemail you but missed my window of opportunity. So I wanted you to have my email address.
shoafy@aol.com
Please write.
I hope this gets to you, in the midst of this thread since a new thread is not working.

donna

 

Re: Pulse!!! Are you here??? » Donna Louise

Posted by pulse on July 2, 2006, at 5:56:56

In reply to Pulse!!! Are you here??? » pulse, posted by Donna Louise on July 1, 2006, at 22:30:02

GOT IT and ty so much, donna!

i'm working on an email to you as i write this. it will be coming to your's from a certain 'msprs.'

be well, my friend,
pulse

 

Re: Another Sticky Emsam Issue » SFY

Posted by Donna Louise on July 2, 2006, at 6:35:27

In reply to Another Sticky Emsam Issue, posted by SFY on June 30, 2006, at 14:48:25

> Speaking of Emsam's sticking power, I do have one dilemma - namely, the need to rotate the location of the patch. Unfortunately, I have both an excess of body hair on my thighs and chest which preclude me from putting the patch on there. In addition, I have quite a bit of old scar tissue on my back which would likely be a barrier to the transdermal delivery system.
>
> The best and most logical place for the patch is my upper arms which I can alternate from day to day. As I haven't had any rash or other skin reaction I don't see this as a problem but I'm wondering if anyone else sees any potential pitfalls in this approach?

I had tried different places "all over my body" (where does that come from..some 60's show?) and I find it sticks great and am having no problems at all alternating between one hip and then the other.
Right now I am doing 9mg and 1/2 6mg but when I get to the pdoc next week I will get a regular 12mg patch. That thing should be huge! But no worry, my hips can accomodate that. Not that they are big hips.. there is just alot of room there, no hair and don't bend much. So I just use one side then the other. I move somewhat to the right or left so it is not exactly in the same spot.
That said, emsam has not been all that I had expected but I have unrealistic expectations. It is better than everything else and am trying some stategies (more klonopin, less provigil and adding lamictal) for the weird agitation. I have what I think it was Zeitguest was talking about, same experience. I feel more depression alleviation on 12mg and still don't have a problem sleeping. I know that is rare, makes me think I am just a regular ol' unipolar with some bad anxiety. I am overall satisfied with the minimal side effects of agitiation and irritabilty, the improvement in social anxiety and the energy that I was sorely lacking. I would say it is a success story. I hope that gives hope. Maybe alot of us just need the higher dose. And I am eating tofu without a problem. It is the only thing on the list that I do eat so I dont miss any of the other things. I don't think food is going to be a problem, I think the problem with the higher doses is an increase in contradicted med sensitivity but I don't take any of those other meds anyway either. As long as I can have some morphine, morphine-derivitive for pain, that is fine with me. I don't get colds or allergies so that is a non issue too.
That is enough from me!

donna

donna

 

Re: Pulse!!! Are you here??? » pulse

Posted by Donna Louise on July 2, 2006, at 7:00:52

In reply to Re: Pulse!!! Are you here??? » Donna Louise, posted by pulse on July 2, 2006, at 5:56:56

> GOT IT and ty so much, donna!
>
> i'm working on an email to you as i write this. it will be coming to your's from a certain 'msprs.'
>
> be well, my friend,
> pulse

Oh whew, I was stressing out about this! I will await your email and then send you the babblemail.
Ok, that is all the off topic I am going to write, Dr Bob!! Just had to make contact and the new thread wouldn't show up.
Thanks,

donna

 

Re: Who's Still Going Strong with EMSAM?

Posted by lisa67 on July 2, 2006, at 11:12:37

In reply to Who's Still Going Strong with EMSAM?, posted by jealibeanz on June 24, 2006, at 21:48:28

I have been on Emsam for 2 wks and have mostly postive results. Started w/ cutting the patch in 1/4 then up to 1/2, now full patch 6 mgs. I take it off before bed and sleep great. My side effects are: a little agitated by pm., can't even handle 1 beer. Positve side effects are: energy, motivation, sex drive, and of course depressed thoughts almost all gone. Love it compared to everything else I've tried.

 

Re: Who's Still Going Strong with EMSAM?

Posted by jealibeanz on July 2, 2006, at 13:54:45

In reply to Re: Who's Still Going Strong with EMSAM?, posted by lisa67 on July 2, 2006, at 11:12:37

Lisa, what else have you tried? Do you have mainly depression or anxiety?

 

Re: Another Sticky Emsam Issue

Posted by jealibeanz on July 2, 2006, at 13:57:29

In reply to Re: Another Sticky Emsam Issue » SFY, posted by Donna Louise on July 2, 2006, at 6:35:27

Yeah, that does give some help. Thanks. I wonder if people could be started at 12mg to get the MAOI A involvement. Does it require a titration like the SSRI's?

 

Re: Who's Still Going Strong with EMSAM?

Posted by lisa67 on July 3, 2006, at 18:19:11

In reply to Re: Who's Still Going Strong with EMSAM?, posted by jealibeanz on July 2, 2006, at 13:54:45

I have tried all the SSRI'S, wellbutrin, effexor and serazone. All had bad side effects, tired all the time, sat on the couch and ate....gained weight, couldn't concentrate and my memory shot. I mostly have depression with some anxiety. I have cut back on caffeine over the past year and my anxiety has greatly improved.


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