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Dr. Bob is Robert Hsiung, MD,
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Posted by BrittPark on December 16, 2002, at 10:07:03
In reply to Re: DrBob, anyone- percocet effexor same family?, posted by djmmm on December 16, 2002, at 8:23:27
Hi,
I hadn't heard that. Where did you find that? According to the prescribing information Effexor is an inhibitor of NE and 5HT reuptake and a weak inhibitor of DA reuptake. Remeron is an antagonist of presynaptic 5HT receptors. However the prescribing information may be incomplete.
Cheers,
Britt
Posted by Kenneth Copeland on December 16, 2002, at 10:44:10
In reply to Re:Withdrawl » zinya, posted by jmmrc2002 on December 16, 2002, at 5:02:39
> Zinya,
>
> I know that I am late in responding. I'm just reading the messages from early Dec. For me, I have the dizziness after only a few hours of missing a dose. It is so bad that I have no recourse but to take my dose. It stops about 45-60 minutes after taking the medicine. I am trying to wean myself off. I am at the 75mg level after being at 225mg. I haven't tried dropping to the 37.5 yet. I was given a sample pack with only a week's supply of 37.5mg. Will this be enough? Should I take the 37.5 longer before quiting altogether?
>
> I was Never On such A High Dose, but I can tell you that a week of 37.5 probably will not be enough,you will need at least 2 weeks worth..It has been 8 days since I have taken that stuff and all withdrawl symptoms exceopt for some slight vertigo effects..STILL!..have gone.The weaning process takes time.Be patient. After you do come off completely buy some Theraflu Nightime and take it for thw withdrawls. Good Luck
Posted by zinya on December 16, 2002, at 11:34:20
In reply to Re: Effexor --some little big Qs (to Bizzou and all) » zinya, posted by khead on December 15, 2002, at 14:18:18
Thanks, khead, for your response. I wrote you back yesterday but now it's not on the screen, so i guess it got swallowed in cyberspace somehow ... and now am searching to recall what i had said and asked :) ...
I've now seen your earlier post too which helps to understand how long you've been on Effexor and your 'symptoms' thus far...
I certainly identify with the waking up at 4-5 am and then flipping in bed with that interminable stream of screwed-up thoughts... I still have yet to start trying Effexor. Once I read on here about such severe-sounding side effects and even withdrawal after just a few days, i confess i got concerned (my md. hadn't told me of any side effect risks but just the 'plus side' of treating two systems at once - serotonin and norepenephrine)** and I still haven't decided if the risks vs. potential rewards would favor at least a trial. My system has over the years been very sensitive to any drugs even when doctors, knowing that, sometimes have had me try less than the minimum-dose pill for starters, so i was grateful to find this site and to at least be forewarned (since Effexor sounds more potent than others i've tried but couldn't tolerate) -- and so far it made me try a while longer 'on my own' but i'm not finding any force for rallying to do the myriad more important tasks awaiting me -- In your words, i do feel "stuck" indeed. (My main concern was a sense of depression but i am starting to realize in past month that anxiety is a lot of what i'm dealing with.)
Well, i do thank you and i will be glad to hear your input. Right after I first posted here, there seemed to be a sudden lull and few postings so I am appreciating discovering a batch of new posts here to reflect on.** After finding and devouring posts on this site, i re-asked my md. -- internal med. not a shrink -- and he said he has approx 200 patients on Effexor and none with side-effect problems that he knew of. That became kind of mind-boggling (as if he were doling it out -- 200 seems like a lot of patients on it for one md.) and also curious or hard to believe, after reading here, that none of them would be having problems...
Posted by jannbeau on December 16, 2002, at 11:55:42
In reply to Re: Effexor --some little big Qs » khead, posted by zinya on December 16, 2002, at 11:34:20
>>>Absolutely agree that it seems strange that, with 200 patients on this medication, none has complained of any significant side effects! What, he has the perfect patient, or 200 of them???
Cheers and Hopeful Holidays,
JannbeauThanks, khead, for your response. I wrote you back yesterday but now it's not on the screen, so i guess it got swallowed in cyberspace somehow ... and now am searching to recall what i had said and asked :) ...
>
> I've now seen your earlier post too which helps to understand how long you've been on Effexor and your 'symptoms' thus far...
>
> I certainly identify with the waking up at 4-5 am and then flipping in bed with that interminable stream of screwed-up thoughts... I still have yet to start trying Effexor. Once I read on here about such severe-sounding side effects and even withdrawal after just a few days, i confess i got concerned (my md. hadn't told me of any side effect risks but just the 'plus side' of treating two systems at once - serotonin and norepenephrine)** and I still haven't decided if the risks vs. potential rewards would favor at least a trial. My system has over the years been very sensitive to any drugs even when doctors, knowing that, sometimes have had me try less than the minimum-dose pill for starters, so i was grateful to find this site and to at least be forewarned (since Effexor sounds more potent than others i've tried but couldn't tolerate) -- and so far it made me try a while longer 'on my own' but i'm not finding any force for rallying to do the myriad more important tasks awaiting me -- In your words, i do feel "stuck" indeed. (My main concern was a sense of depression but i am starting to realize in past month that anxiety is a lot of what i'm dealing with.)
> Well, i do thank you and i will be glad to hear your input. Right after I first posted here, there seemed to be a sudden lull and few postings so I am appreciating discovering a batch of new posts here to reflect on.
>
> ** After finding and devouring posts on this site, i re-asked my md. -- internal med. not a shrink -- and he said he has approx 200 patients on Effexor and none with side-effect problems that he knew of. That became kind of mind-boggling (as if he were doling it out -- 200 seems like a lot of patients on it for one md.) and also curious or hard to believe, after reading here, that none of them would be having problems...
Posted by djmmm on December 16, 2002, at 13:28:32
In reply to Re: DrBob, anyone- percocet effexor same family? » djmmm, posted by BrittPark on December 16, 2002, at 10:07:03
all of that is true, however, both drugs have some effect on the opioid system...
Posted by Sioux on December 16, 2002, at 13:42:02
In reply to Re: Effexor --some little big Qs » khead, posted by zinya on December 16, 2002, at 11:34:20
>>> and he said he has approx 200 patients on Efexor and none with side-effect problems that he knew of.
May I reflect on this a moment? In my years as a patient with chronic illness (a cluster of autoimmune diseases) I have observed this kind of misinformation many times. My conclusion is that such claims tend to be more naive than ill-intended.
Many docs have a 'chilling effect' on a patient's inclination to speak up. They are bad listeners, or they are so eager to help that they "cue" a patient to please them, or they are genuinely unaware of how much they don't know (and therefore where/how to get informed), or they genuinely believe that a patient is better off if gently manipulated away from self-experience, or they are so frightened of their responsibility as physicians that they *have* to overbelieve themselves. A great variety of very human engines that may be driving this tragic claim.
That leaves you to make the decisions about your health care. This is often a responsbility many folks don't want. But there it is.
It's clear that you are accepting this responsibility. You are informing yourself. You are weighing the price/promise balance. You're taking your time.
For my part, my initial strong negative reaction to Effexor was probably about my sense of outrage and betrayal at my doc's not having informed me of the nature of the drug. This left me feeling horribly vulnerable and betrayed. It felt as if someone ahd told me that they were going to take my tonsils out when in reality they were planning to do experimental brain surgery.
However once I had informed myself and reclaimed my power to care for myself, I was able to choose to use the drug and am satisfied with the results. My life is better with the drug than without.
I hope you find this to be a useful observation and look forward to your feeling better. It's much more fun that way.
--S
Posted by jannbeau on December 16, 2002, at 13:42:24
In reply to Re: DrBob, anyone- percocet effexor same family?, posted by djmmm on December 16, 2002, at 13:28:32
> Both peer-reviewed papers were authored by the same researchers(Schreiber et al, if I remember correctly). Replication by esearchers unassociated with the original researchers . . .?
Also, might wish to further define "family of drugs" vs "drug class" vs "chemical class" vs "therapeutic class"??
Cheers,
Jannbeau
all of that is true, however, both drugs have some effect on the opioid system...
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11931344&dopt=Abstract
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10505622&dopt=Abstract
Posted by djmmm on December 16, 2002, at 18:33:31
In reply to Re: DrBob, anyone- percocet effexor same family? » djmmm, posted by jannbeau on December 16, 2002, at 13:42:24
Effexor and Opioids may be in a similar "therapeutic class" but only because Opioids make great antidepressants...
Posted by blueheron on December 16, 2002, at 20:01:04
In reply to Re:Withdrawl » zinya, posted by jmmrc2002 on December 16, 2002, at 5:02:39
Hi all...
I'm new to this thread, been on effexor for 10 months now, and thought I might as well add my thoughts on withdrawl... In July I decided I was sick and tired of the sexual side effects, (decreased libido due mainly to frustration with delayed orgasm) and unbeknownst to my doctor, I decided to see what these much feared withdrawl symptoms were all about... also, I wanted to know if I was going to be hooked forever, or if I could get off the stuff... so I quit cold turkey from 150/day.
The first symptoms I felt started two days later, every time I moved my eyes I heard a whooshing sound, sort of like driving in a car with the window down going past telephone poles. Then I started feeling the electric jolts everyone talks about. I must admit it was a little disconcerting, but nothing too dramatic, not as bad as I had been led to belive... I also experienced the depth perception issues, everything looked far away, and I felt a compulsion to mimic a sort of robotic movement... short crisp jerky movements felt "good"... could be I have a bit of experience in this area, I did inhale in my youth, so to speak, and I think anyone who has ever experimented with psycoactive drugs would recognize these symptoms...
Anyway... Much to my relief the sexual side effects went away just as my Doc had said they would, in fact they departed faster than I expected, within a few days. I started to go into a prolonged manic phase, lasting probably 2 weeks, even though I was still feeling the aforementioned side effects, (in fact they were increasing in severity, particularily the electric jolts, the eye movement/sound and the depth perception) I felt great, I started to wonder if my seratonin levels had somehow been kicked into high gear.
But... (there always is a but, isn't there)
After another couple of weeks I noticed the manic high was wearing off, in fact the depression was returning... the good news is, the side effects all went away, the whole withdrawl process lasted about 6-7 weeks... no more shocks, no more eye stuff... great sex!!!, but I could feel myself sliding into the pit. So I started to have second thoughts about my cold-turkey decision.
Bottom line... I went back on Effexor, 75/day for 3 days then 150/day... I figure my little experiment set me back 4-5 months, I started to feel and remember the first recovery, recognized the light at the end of the tunnel a lot faster, and can see the positive effect it is having on me.
Yes the sexual side effects are back, but not as bad this time, because I know they are transitory, and because I would rather feel like I do now then as I did. Depression sucks, and in my opinion effexor rules.
Posted by blueheron on December 16, 2002, at 20:18:48
In reply to Re: Effexor XR? Successful but very ugly! » Dan L, posted by zinya on December 2, 2002, at 15:15:23
I give myself about a 4 hour window to take my pill... if i miss it, i miss the day, sure i feel it the next day, but that just is a reminder... usually i start feeling non-specific, non-directed rage the next day... I just remind my loved ones what is happening... and carry on
> Dan L (or anyone):
>
> When you missed doses, how long was it before these symptoms would show up? What if you were a few hours late on a given day? Would it be like an 'alarm clock' of these electric sensations reminding you to take dose? And then how soon would they subside after resuming dose??
>
> It sounds like Effexor -- which I was prescribed but haven't yet started (i've written a few queries some days ago) -- might be wrong for someone (like me) who's easily distracted as to time of day or remembering to take a pill at a fairly rigid time every day - ??
Posted by JESSsMom on December 17, 2002, at 5:18:12
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
Sorry if I'm reposting, can't get the hang of this board yet.
I am wondering if anyone who's GAD symtpoms have lessened on Effexor XR but their energy level, fatigue, and verocious appetite have returned?
The addition of Wellbutrin seems to be an option but at what dose?
Any thoughts appreciated.
JM
Posted by blueheron on December 17, 2002, at 13:53:38
In reply to Effexor and Me =), posted by ¥ã£ér|é on June 17, 2002, at 16:23:43
> .. Tried to wean off about 10 months into the program (just felt I didnt need it any more), Withdrawls were horrible, the most prevalant was the "eye shocks" or "eye seizures" I experienced. Took me off of work for 3 days. After about 5 days of withdrawl symptoms, I was on "top" of the world !!! OMG I never felt so good in my life !! .. that euphoria lasted for a total of 2 weeks ..
BH] Sounds just like me! What a HIGH!!!, then what a drag
>I began having small anxiety attacks again, and unfortunatly had to return to the medication. But it was okay with me, Effexor XR has done wonders for my life. I can think again clearly and make informed decisions. I am now on 150 mg a day and am doing very well. I have no desire to come off this med, for fear that I will loose the ground which I have gained.BH] I figure my going off set me back about 6 months, and I too am happy to be on it again.
>Although today was interesting, and I will share this experience with my doctor. I suddenly developed "eye shocks/seizures" out of the blue. I was brought home from work roughly 15 minutes of being there, I could not focus my vision and couldnt move suddenly, dizziness was pretty severe. ... The only thing I can attribute to this is that I did miss my dosage yesterday, but I have missed dosages before and never had this reaction.
BH] I get that every time I forget to take my pill, but since stopping and re-starting it seems I am more sensitive to the dosage changes... when I went from 150 to 75 to 0 in 2 days I got incredible non-specific, non-targeted rage (won't do that again :-), had to warn my friends to stay away or die)
>I am sharing this information to all who are either veterans of Effexor or new to the drug. I will not change medications, nor have I tried any other anti-depressant. Effexor works well for me and if there are a few inconveinences once in a while.. I'll live with it.
BH] Although I could stand to have a "quickie" once in a while ;-), now it takes forever to cum, even my lady gets distressed at the third application of KY
Posted by Scot_lass2003 on December 17, 2002, at 20:39:01
In reply to Re: Effexor --some little big Qs » khead, posted by zinya on December 16, 2002, at 11:34:20
Hi all
I am qite new to effexor(6 days) and am experiencing an almost constant sense of motion sickness as well as awful headaches.Am on 37.5mg at the moment but will move to 75mg in 2 days. Please tell me it gets better!!!!
Posted by EGR on December 18, 2002, at 10:01:02
In reply to Re: Effexor --some little big Qs (nm), posted by peterjg on December 17, 2002, at 21:41:05
I was on 150 of Effexor XR and all I could do was sleep. I wasn't suicidal, so that was good... in fact, it was weird... I was high, yet drowsy. I only lasted about a month.
Posted by sly on December 18, 2002, at 10:25:38
In reply to Re: Effexor --some little big Qs, posted by Scot_lass2003 on December 17, 2002, at 20:39:01
I know exactly what you mean about the headaches and motion sickness, I also had poor balance, I found myself actually falling over when I bent down to tie my shoes or put socks on.
Don't worry, all of the side effects go away with time, the length of time ranges, some last a few days, some a few months. The most disturbing were the sexual side effects, but even those are gone now (I was on 37.5 for 2 weeks, and 75 for 9 mos now).
Posted by Scot_lass2003 on December 18, 2002, at 13:36:43
In reply to Re: Effexor --some little big Qs, posted by sly on December 18, 2002, at 10:25:38
> I know exactly what you mean about the headaches and motion sickness, I also had poor balance, I found myself actually falling over when I bent down to tie my shoes or put socks on.
>
> Don't worry, all of the side effects go away with time, the length of time ranges, some last a few days, some a few months. The most disturbing were the sexual side effects, but even those are gone now (I was on 37.5 for 2 weeks, and 75 for 9 mos now).Thank you for the reassurance. What sexual side effects and are they only for men? Is the medication helping in general & if so how do you feel better(ie what is different for you on the medication)
Posted by khead on December 18, 2002, at 13:36:59
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
I'm 3 weeks in, and just started the 150/day
dose...noticed I was jittery and had some
ringing in the ears. Checked my BP and find I'm at 185/105 heart rate at 105 resting! (I've always been somewhat high at around 135/90.) Called my Doc and he told me to ramp down. Dropping to 75 immediately. Probably will go to something else. Sad thing is the stuff seemed to be working. Anyone had a similar experience?
Posted by Scot_lass2003 on December 18, 2002, at 13:37:17
In reply to Re: Effexor --some little big Qs, posted by sly on December 18, 2002, at 10:25:38
> I know exactly what you mean about the headaches and motion sickness, I also had poor balance, I found myself actually falling over when I bent down to tie my shoes or put socks on.
>
> Don't worry, all of the side effects go away with time, the length of time ranges, some last a few days, some a few months. The most disturbing were the sexual side effects, but even those are gone now (I was on 37.5 for 2 weeks, and 75 for 9 mos now).Thank you for the reassurance. What sexual side effects and are they only for men? Is the medication helping in general & if so how do you feel better(ie what is different for you on the medication)
Posted by peterjg on December 18, 2002, at 13:51:13
In reply to Re: Effexor --some little big Qs, posted by Scot_lass2003 on December 18, 2002, at 13:36:43
The main Sexual Side-effect appears to be delayed ejacualtion for men. I only know this from what I have been observing here in these postings. My depression has happened since I've been seperated from my wife who I adore. So I can't comment from first hand experience. seperation=No Sex.
Posted by peterjg on December 18, 2002, at 13:57:27
In reply to Re: Effexor --some little big Qs, posted by Scot_lass2003 on December 18, 2002, at 13:37:17
I forgot to say that even though I've only been on the meds for 2 weeks It is apparently working. I haven't broken down in a while and I've been able to think more clearly. I have noticed an increase in general nervousness but nothing to bad, rather mild. Before I started taking Effexor I would cry 3-4 times a day. Now I may get down, but that's to be expected I guess. I miss my wife terribly.
Posted by sly on December 18, 2002, at 16:46:11
In reply to Re: Effexor --some little big Qs, posted by Scot_lass2003 on December 18, 2002, at 13:37:17
I'm female, for me, I had no sex drive, the few times I did try having sex with my boyfriend I couldn't have an orgasm, I would get a pleasurable feeling, but it was incredibly frustrating because there was no release. After a few months of this I just gave up.
Overall, I had highs and lows over the first 6 months on this medication. Now after 10 months life is great and back to what I consider normal (with the exception of the christmas blahs).
Before effexor I cried all the time, was promiscuous, insomnia, constantly tired, anxious, annoyed, I didn't want to do anything or see anyone, I felt worthless, useless, and just plain empty.
After a few months that started to change, I felt more energy, the biggest difference was the increase in my ability to concentrate. I no longer sat at work pretending to read, I could actually function! I began sleeping through the night and was able to get out of bed in the morning without being dragged. My sex drive and function was the last to come back, but it seemed to fall into place once the rest of me felt "whole" again.
Posted by smokey on December 18, 2002, at 19:50:33
In reply to Monthly Update of my Experience on Effexor, posted by h20surfer1 on December 10, 2002, at 0:13:15
I, too, started on Effexor (the XR). I've been on it a month, am up to 75mg. Started on 37.5 for 2 weeks, then 75. It's for depression/anxiety. Have been on (over the last 11 years) nortryptyline (pooped out), then Celexa, which after a while "hypered me up" too much. Affected my sleep too much. I tried Wellbutrin but felt like a raging bull.
Effexor has been great. I have good energy- drink a cup of coffee in the morning and I can get a lot done! I have a positive outlook, the worry is greatly decreased. My sleep is much better now. Not too many side effects, some dry mouth, no GI effects. I feel a little fuzzy but much better than when I take nothing! Compared to me off the ADs, this is better (though not perfect.)
Overall, it suits me. I was worried after reading others' bad experiences, but I tried it. My appetite has decreased, I don't have the carbo cravings I did on Celexa. But, I sure miss the wonderful dreams I had on Celexa!
As for sex life, well, how to put it delicately? Libido OK, orgasm is 4 or 5 little ones compared to one regular one before. (I'm female.) Guess I can't complain............
> I have been posting monthly.
>
> I take 225mg/day of Effexor and was started on 15mg/day of Remeron 30 days ago (for Libido problems from Effexor). I have been on effexor for almost 6 months now.
>
> I am still having positive results from Effexor. No depression, no loss in energy, very little anxiety (too much of a reduction and you lose motivation) great sleep (Remeron really helped this), and my libido is slowly starting to return.
>
> I am overall very happy with the results of the meds and will continue to take them until I am directed by the Doc to stop. I have to honestly say that I feel better now than I have since childhood.
>
> Hope this helps for some of you coming to this sight just starting out. The side effects go away and the results have been worth it for me.
Posted by johnj on December 18, 2002, at 21:15:16
In reply to Re: Monthly Update of my Experience on Effexor, posted by smokey on December 18, 2002, at 19:50:33
HI Smokey,
I am currently taking notryptline and about a year ago started having problems after starting to excercise. Upping the dose makes things worse and lowering the dose almost did the same. Sleep has been horrible. How long did it take for the nortr to poop out on you? I started taking it at 27 years of age and that was 10 years ago. I can't seem to excercise which is very frustrating. Could you tell me if you tried any other TCA's and HOW did you get off nortryptline?
Thank you very much
johnj
Posted by Kris21 on December 19, 2002, at 3:10:29
In reply to Re: Effexor XR? Successful but very ugly!, posted by blueheron on December 16, 2002, at 20:18:48
I've been on Effexor XR for 6 months now. 75mg a day. I was previously on Prozac for 3 months but didn't sit well with me. The Effexor has definitely helped, especially in the first few months but i can't help feeling that i'm still not all the way there or that the effexor is losing its effectiveness. Not sure if depression is still somewhat there or if it is side effects causing problems. I feel tired and could sleep all day. Have occassional heart palpitations and anxiety that my heart is gonna stop. Not sure if I need to up dosage or if that would make things worse. Thinking about switching to the new lexapro (new form of Celexa), or adding something on top of the effexor like wellbutrin. I've done lots of research in hopes of finding an answer so i can have my life back to the way it was. It just seems like there is little hope for complete recovery. I'm also afraid to stop the effexor. I have tried weening off it and have those terrible withdrawl symptoms like the whooshing sound and electrical shock sensations and severe anxiety. Trying to fight this desease seems more depressing than the depression itself! On another note, I'm positive that my depression and anxiety was a result of ecstacy use. Are there any meds that work best specifically for ecstacy-related depression?
I'm desperately seeking answers...
Posted by daizy on December 19, 2002, at 8:42:19
In reply to My Effexor experience, posted by Kris21 on December 19, 2002, at 3:10:29
> I've been on Effexor XR for 6 months now. 75mg a day. I was previously on Prozac for 3 months but didn't sit well with me. The Effexor has definitely helped, especially in the first few months but i can't help feeling that i'm still not all the way there or that the effexor is losing its effectiveness. Not sure if depression is still somewhat there or if it is side effects causing problems. I feel tired and could sleep all day. Have occassional heart palpitations and anxiety that my heart is gonna stop. Not sure if I need to up dosage or if that would make things worse. Thinking about switching to the new lexapro (new form of Celexa), or adding something on top of the effexor like wellbutrin. I've done lots of research in hopes of finding an answer so i can have my life back to the way it was. It just seems like there is little hope for complete recovery. I'm also afraid to stop the effexor. I have tried weening off it and have those terrible withdrawl symptoms like the whooshing sound and electrical shock sensations and severe anxiety. Trying to fight this desease seems more depressing than the depression itself! On another note, I'm positive that my depression and anxiety was a result of ecstacy use. Are there any meds that work best specifically for ecstacy-related depression?
> I'm desperately seeking answers...Kris, I know what your going through cause its happening to me also. Ive got depression& anxiety, and am also sure a lot of its down to previous drug use. Im just trying to stop effexor, was on 150, am now down to 37.5, and the withdrawal is bad. Im stopping it cause I think it made me worse, the side effects were horrible. Whats weird is that trying to find an AD to make me feel better is actually making me feel worse as Im starting to think it might never happen, and I'll always feel this bad. How long were you using Ecstacy for, are you still doing it? Im not sure if I should just go back to doing it because if im never going to feel normal again, then I might as well try and enjoy myself how and when I can (trouble is that its kind of not the same as it was in the beginning). I havnt yet been put on on any other meds, but feeling better than when I was on the effexor, so i suppose thats one good thing.................. Here's hoping!
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