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Posted by befree on November 22, 2002, at 22:29:40
In reply to Re: Anyone had success on Effexor XR? » Redula, posted by jannbeau on September 24, 2002, at 16:35:15
I took Effexor XR for two weeks and decided to go off of it because I was experiencing severe sleepiness and felt real spacey. I went off the medicine abruptly and didn't think that I would experience very many side effects because I was only on it for such a short while. Three days after withdrawing from the medicine I am experiencing bad lower abdominal cramping type pain, and dizziness? Is this normal? Any body else experience anything like this? If so, how long did it last?
Posted by Sioux on November 22, 2002, at 22:34:03
In reply to Re: Effexor dose levels and effects? Cam? anyone?, posted by Zinya on November 22, 2002, at 14:48:01
Zinya, if you have 'low adrenaline' and tested low - this would be a 'cortisol challenge' test + a 24 hr urine cortisol - you should be on adrenocorticosteroid replacement such as prednisone or cortef + florinef. Low adrenal function causes depression and fatigue.
S
Posted by Sioux on November 22, 2002, at 22:36:43
In reply to Re: Effexor dose levels and effects? Cam? anyone? » Zinya, posted by jannbeau on November 22, 2002, at 16:43:10
Jannbeau, *be* didactic. I love it. Thanks. S.
Posted by zinya on November 23, 2002, at 0:01:21
In reply to Re: I am scared of this medicine, HELP ME!, posted by dde on November 22, 2002, at 22:25:58
thank you, dde... and i'm sooo sorry to hear of your own loss ... As my mom had had the experience of losing her son, my brother, i can imagine from close proximity the added grief of such a loss... And I wish *you* well ...
i have days (or rather hours of each day) when i feel it's still so recent - and it was all too sudden so that i still have recurrent flashes of denial mixed in -- that i 'forgive' myself or indulge myself or whatever it is for having zero energy and doing nothing but the minimalist of tasks and sometimes getting rather bleak. But interwoven with those voices are others that surface which are more "social" voices and especially "American" voices that are in me whether i believe they're "right" or not and they berate me or even shame me a bit as floundering and thinking i should have more energy by now, that this vegetative-seeming state should be further ... I know cognitively to be wary of "shoulds" -- and i do attend a bereavement group every 2wks -- although it's possible that missing the last meeting was either a cause or an effect of gettiing to a place where i finally this week started thinking i had "gone long enough" -- and one particularly horrid night's sleep Wed. night waking with awful thoughts and anxieties about the future too made me think i had to start some kind of a-d ... despite some past experiences, as i mentioned earlier that never yielded any relief ... But i am now -- as I sense you are suggesting -- pausing a bit more before starting, being reminded (thankfully - whatever i decide) for this website giving me your voices and helping me at least be more aware of a bunch of pros and cons that i would otherwise have been potential ambushes i could ill afford (who can?) ... With holidays coming up i think i may have also started to feel a bit panicky in a way (an energyless sort of way) cuz like many, it seems, i have trouble on the inside during this season even though i didn't usually show it ... but indeed, perhaps i can weather some more time to see that grief's process before adding meds to the mix... In he interim, i'm starting even tonight to think that now five days since having any alcohol, which i had let become a rather nightly way to take the edge off, even though it wasn't much, it was pretty routine and laying off alcohol since last Sunday might be starting to pay off a bit too... Thanks for the encouragement.
And again my deepest condolences to you, de...
Posted by zinya on November 23, 2002, at 15:22:45
In reply to Re: Effexor SR, posted by Bizzou on November 11, 2002, at 23:14:23
The post that specifically triggers this post and several specific Qs and one bigger/broader Q is Bizzou's (nice tag name :)) and a comment she/he made:
"I am quite positive this Effexor will help me but I thing that eventually you have to quit. But before I do quit these drugs, I will have resolved the inner reasons for these **inappropriate feelings**. I'm planning to see a psychologist with experience in PNL and with those two aids (effexor and PNL), I should feel better again." [**s added]
First, some clarification Q's:
a) Bizzou's post was titled Effexor SR -- is that different from XR? or perhaps a typo? or what it's called in Canada where Bizzou is?b) what is PNL ?
Finally, the meatier question which Bizzou's post prompted in referring to "inappropriate feelings." I mentioned yesterday that I'm in a time of huge loss -- of my mom in August -- leaving me as the one surviving family member (except for cousins and nieces, nephew, none of whom I am close to in our adulthoods). I have great friends who are loving and supportive and some of whom are urging me to see what i'm going through as 'normal', others of whom though now that I mention I am considering perhaps needing an a-d say "yeah, maybe so" -- reflecting both their concern, their wish to see me more active again, and their lack of fresh experience if any with this grieving process. This mix of voices mirrors my own internal voices of "give the grieving more time" vs "i *should* be moving on by now." ...
Bizzou's phrase made me think about the convergence of plenty of "things to be depressed about" - not only my mom's loss but also the 'high and dryness' of my own life and where to go from here - i had (quite willingly) resigned from my professional job (mostly cuz i didn't like where i was living) and moved back to where my mom was after 5 yrs of her being diagnosed with alzheimer's and trying to essentially parent her from 2,000 miles away. And I wound up buying a home for her to be with me because two diff. retirement homes she was in had screwed up royally enough that i just wanted her with me, but now i face a HUGE sense of zero on the horizon, a sense of absolute loss not only of a precious mom who also, consciously or not, gave meaning and sense to many big and little orderings of priorities in my life, and now there's this void of purposelessness, not knowing where i'm going -- themes echoed by others in my bereavement group whose parents' deaths were longer ago than my own. Which on the one hand weighs in on the side of feeling "well, okay, this is normal... Don't overreact to this amount of zero energy and depression." On the other hand, this extra component of also being high and dry, with a sense of relative (not supreme but relative) urgency to "get on with my life" for financial as well as other reasons yet finding no energy to even finish unboxing and moving into this house, which represents a decision that turned out to be made on ill-informed grounds given that mds had failed to diagnose that my mom's pains for a year were due to cancer and their encouragement even that i get a home and move mom in with me cuz they saw what a caring daughter i was -- all that prompted a decision to invest in a house which now feels rather like an 'albatross' and a daily constant reminder of all that is lost and wound up having only 5 months living here with mom when i'd imagined at least 5 years as realistic...
In sum, and to get to my question, how many of you would say that your feelings of depression strike you as "appropriate" vs. "inappropriate" given the realities in your life? Or does that strike you as an irrelevant Q? Are others similarly taking a-d's because of feelings that what may have once been appropriate levels of depression have at some point turned 'inappropriate'? I'm guessing many of you, like me, have total lack of energy as a final straw kind of thing that has led to a pharmacol. approach ???
I took the Depression test that was on a website on washingtonian.com mentioned by one of the posters here - apparently a classic 'test' on a 54 point scale where anything over 20 points is consdiered 'major depression' and, while it's hard to know how to quantify some of the responses, i seemed to be somewhere in the level of 15 points plus or minus. It also made me wonder if the risks of taking such meds - which I confess have been very important to hear and rather bracing to learn of on this board -- that perhaps i should be asking myself more importantly just how "inappropriate" these feelings of depression are... before risking something that could be a boon but, quite obviously, could just as easily be a new kind of nightmare given what some report here (plus my own history of trying a-ds or bipolars in past 15 yrs a few times to no avail).
Any thoughts will be MUCH appreciated - and I apologize for being so wordy. My censor is on hiatus too.
thanks :)
Posted by zinya on November 23, 2002, at 15:26:46
In reply to Re: Effexor SR, posted by Bizzou on November 11, 2002, at 23:14:23
While I'm at it, another Q:
Is anyone here familiar with Lexapro? I had heard of it via both a friend whose daughter is taking it and from my bereavement counselor who had heard good things about it. But my md. said it was too new, he'd never used it, and raised Effexor instead, as I mentioned in prior post. But since I've put on hold starting the Effexor until i process more all your postings, I'm curious if any of you have any experience with or knowledge of Lexapro (apparently an SSRI that is supposedly a newer, less-side-effect version of Paxil et al.) ???
Posted by Fee on November 23, 2002, at 18:33:50
In reply to Re: starting effexor... keep posting.. success/dosage?, posted by lg on November 7, 1999, at 19:11:05
Interesting stuff about Effexor/Remeron combination. I am on Zoloft and Remeron, but the Zoloft has 'pooped out' I think, after 12 years on it. (See thread 'SSRI Poop Out'). My doctor is switching me to Effexor and keeping me on the Remeron. Anyone else had experience of these two drugs in combination?
Fee. xxx
Posted by Fee on November 23, 2002, at 19:48:38
In reply to Effexor; came and went, posted by Paul 1952 on October 25, 2002, at 23:28:07
Paul, I know its a long time since you posted this message, but I found it interesting and wanted to thank you. I am a 38yr old woman who has been on ssris for twelve years - very successfully up until six months ago. I am suffering from drug 'poop out' effect, where the drug just stops working. My doctor is considering putting me on Effexor. But the last time I tried to come off the ssri (lustral) that I have been on for years, I got this constant light headed feeling, like my brain couldn't keep up when I moved my eyes or head. It was really horrible and weird. Did you go through that too? Now that youv'e been off the drugs for a bit longer, are you feeling ok? And, if you don't mind me asking, did you have any side effects with Effexor that affected your sex life? Thanks again for your message. All the best,
Fee
Posted by oscarcatt on November 23, 2002, at 23:28:05
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
Yes, I have had good success with Effexor XR. I am on a high dosage of it. I've been on meds for 10 years now and been through quite an assortment of them, some with some success, some with absolutely none.
I used to have nausea from the Effexor. The nurse practicioner I saw recently suggested that perhaps I had an ulcer. This time while taking it I haven't experienced that. (I had been taking some herbal stuff that seemed to get rid of my constant nausea and it hasn't been back)
However, I've been out for 2 days now and I"m going through bad withdrawl. I don't recall this from the past.
I'm having lengthy vivid bizarre dreams with Effexor.
Posted by jmmrc2002 on November 25, 2002, at 2:35:35
In reply to Re: Anyone had success on Effexor XR? , posted by oscarcatt on November 23, 2002, at 23:28:05
I have found this board very informative.
I've been on FXR for 5 months now. At my last visit to the doctor, she bumped me up from 150/day to 150 twice daily and a drug to help me sleep better.
I have never been depressed before and the symptoms slowly progressed because of situations and circumstances. When the outside influences got better, I felt better. Then the outside influences returned to "normal" and I became depressed again and finally sought the physician.
I generally do not like to take medicine and am very sceptical of doctors. I will take medication when I have to but would prefer to go the natural route.
I also have been diagnosed with hypothyroid. Through various links from this forum, I have discovered that the depression that I have been experiencing could be caused by my thyroid level not being balance even though I am taking the appropriate dose of medication. This doctor, who I saw for the very first time 5 months ago for the depression, never related the depression to my thyroid nor did she inform me that FXR was addictive (causing withdrawls), nor did she explain the side effects. Normally, I read the brochure from the pharmacist, but I did not this time.
I have experienced some of the side effects that I have read about in this forum but didn't relate it to the FXR. THANK YOU!!
Posted by jannbeau on November 25, 2002, at 12:12:23
In reply to Re: I am scared of this medicine, HELP ME!, posted by dde on November 22, 2002, at 22:25:58
> Hi, DDE, I can feel your pain in this post. I wish that I knew how to help you through it, but I think you are doing the very best you can with it. I'd like to say to Zinya that your words seem very wise, so perhaps she can go with what you suggest for the moment as she tries to sort out the differences between grieving and depression. Zinya, I have to think about the questions you asked me in response to my earlier post re pharmacokinetics of Effexor and other ADs.
Jannbeau
First, my heartfelt condolences.
> Second, give yourself time to grieve. I have also lost a loved one, but to depression and Effexor XR. Please do not put a time limit on your grief or try to mask it with medication. It would be my opinion that trying to mask the pain, or the other effects such as no energy and loss of feeling, will only prolong the effects, as I have been told that once you come off the medication the feelings are still there and still have to be felt to get past them. After the death of my son in August, I took some Paxil for the anxiety. I can tell you that I became totally numb to any emotion, and that once I stopped taking it, I was feeling again, sometimes to an extreme, but at least I know it will come and go....not so with the medication....all I felt with it was NOTHING. Allow yourself all the emotion. It is natural and normal. Pain, Guilt, Anger (and this is the worst phase for me, so far, as when I am angry I cry, then become frustrated and cry more), will eventually turn to acceptance and being able to move on. Try to find a group for support. I have had to do that. I try to be kind with myself. The doctors keep trying to get me to take more medication as I have a heart condition and they are afraid of the stress of grief on my heart. I function at work, but on my off days, I find little to get out of bed for....some days I just stay there and FEEL.
> I am told by our grief counselor that grieving has no time limit and takes different routes for everyone. I truly believe it is so.
>
> I hope you will give yourself time: time to feel and time to heal. If the healing doesn't start, if you aren't moving through the emotions, THEN look for the least offensive drug and listen to your body. I will keep you in my prayers. de
Posted by jannbeau on November 25, 2002, at 12:35:00
In reply to Re: Effexor dose levels and effects? Cam? anyone?, posted by Sioux on November 22, 2002, at 22:34:03
> Zinya, take this posting to your doctor and get him to explain the adrenal glands. The information contained below should be clarified by a physician. The appropriate doctor to see is an internist with a subspecialty in endocrinology if your adrenal glands are thought to be malfunctioning.
Jannbeau
Zinya, if you have 'low adrenaline' and tested low - this would be a 'cortisol challenge' test + a 24 hr urine cortisol - you should be on adrenocorticosteroid replacement such as prednisone or cortef + florinef. Low adrenal function causes depression and fatigue.
>
> S
Posted by jannbeau on November 25, 2002, at 12:40:30
In reply to Re: Effexor dose levels and effects? Cam? anyone?, posted by Sioux on November 22, 2002, at 22:36:43
> Ah, Sioux--are you being complimentary or sarcastic? Hard to tell via the electronic medium in which we chat and I would not want to offend anyone here or elsewhere.
Cheers, and Happy Thanksgiving!
Jannbeau
Jannbeau, *be* didactic. I love it. Thanks. S.
Posted by Harry J on November 25, 2002, at 20:48:03
In reply to Re: Anyone had success on Effexor XR? YES! , posted by Shel on July 18, 2000, at 1:35:45
I have been on Effexor XR for about 6 months now. I was first diagnosed with post traumatic shock syndrome in 95 as a medic in Detroit. Shortly after I had a daughter born profoundly handicapped. She died about 7 months ago at age 16. Up until then I had been on just about everything, with Paxil working the longest and best.
Effexor has been a miracle drug for me. However, unlike the typical reaction time for it to start working (usually 2-3 weeks), I have found that it works within a matter of days. Similarly, if I should go without it for more then three days things happen fast. I not only get quickly and deeply depressed, but I actually get psychotic in a way I have never been before. This happened twice, once on a business trip where I forgot my medicine. The second occurance was an admission for chest pain to the hospital. I did not remember the right and told them the paxil. When I left the hospital I did not know who I was or what I did for the next two days. I have never been diagnosed manic or psychotic. I believe it reacts similar to that which Prozac was suggested to have worked: such a fast come down that you actually go far beyond even "your" normal depressive states.
I have no knowledge of anyone else on it and therefore subsequently cannot tell you if this reaction is typical. I am thinking about seeking an alternative medicine, which as you all know is not easy. However to think of going through another episode of withdrawel almost makes suicide look like a much better option. At least that is my opinion.
With regard to Dr. Bob's discontinuation note on the site I also experienced a mild flu like symptom. That was however the least of my worries.
Posted by Sioux on November 25, 2002, at 22:13:41
In reply to Re: Effexor dose levels and effects? Cam? anyone?, posted by jannbeau on November 25, 2002, at 12:40:30
> > Ah, Sioux--are you being complimentary or sarcastic?
> Jannbeau, *be* didactic. I love it. Thanks. >
Complimentary, for sure! I don't do sarcasm. Thanks for clarifying.
S
Posted by Badger on November 26, 2002, at 10:51:56
In reply to Re: Effexer and Effexer xr, posted by jannbeau on September 13, 2002, at 16:39:23
I understand that Effexor XR is an extended release formulation of Effexor (thanks to Jannbeau's posting of September 13), but I'm curious to know what differences, if any, there are in the effects (and side effects) of the two formulations.
By way of background ...
I've just started on Effexor (regular) about nine days ago - 75mg/day (37.5mg in the morning and in the evening). This medication was prescribed by my family doctor - I'm not sure how much experience she has with it or with other anti-depressants, although she is definitely not a 'pill pusher'. At the end of two weeks, I'm supposed to up my dosage to 75mg (2 tablets) in the morning and 37.5mg in the evening, and we'll evaluate from there whether to increase, maintain or decrease that amount. FWIW, I'm a 47 year old man, weighing approximately 95kg (~210lbs).
This is the first time I've taken an anti-depressant, and I realize that it will take some time for my system to adjust. In retrospect, I knew next to nothing when I was prescribed this drug, and have been reading the posts here with great interest. So far I've had a few side effects - nausea for a day or two, some loss of appetite (a good thing in my case), some muscle tension, and fatigue - but overall, nothing too serious. I've been sleeping better than I have for a while, even though I'm still tired. Actually, it's probably too soon to tell, since my insomnia was back last night (I can fall asleep without any problem, but wake up around 4AM and can't get back to sleep). I think I may sleep better if I take my last pill shortly before bedtime, although I need to test this theory a bit more.
It's hard to say whether the drug is having any effect on my depression. I was quite down last Sunday (day 7 since I started), but have had a few bouts of feeling up since then. I realize that it may well take several weeks before I can really judge its effectiveness, and this will also require finding an optimum dosage.
Although some people specifically mention that they have been taking the XR formulation, I don't know if the others (i.e., those who refer only to Effexor) are taking the 'standard' version or just don't bother to spell it out. I'm wondering if anyone who has experience with both could comment on which they preferred and why. Or, if anyone knows of refernces on this subject, perhaps they could respond with links.
I recognize that not everyone reacts the same way to this drug - it can either make you tired or keep you awake, give you constipation or diarrhea, make you gain or lose weight, etc.... Still, I'd like to be able to discuss alternatives with my doctor the next time I see her (in another couple of weeks), and would feel more confident if I knew some of the pros and cons of the XR option.
Thanks in advance for any information that you can provide.
Badger
Posted by jannbeau on November 26, 2002, at 11:24:21
In reply to Complimentary, posted by Sioux on November 25, 2002, at 22:13:41
> > >Well, Thank you, Maam!! I appreciate that --a lot!
Cheers,
JannbeauAh, Sioux--are you being complimentary or sarcastic?
>
> > Jannbeau, *be* didactic. I love it. Thanks. >
>
> Complimentary, for sure! I don't do sarcasm. Thanks for clarifying.
>
> S
>
>
>
>
Posted by sarah w on November 26, 2002, at 17:11:28
In reply to Re: Anyone had success on Effexor XR?, posted by befree on November 22, 2002, at 22:29:40
I've been on Effexor XR for about 8 months now, started off with 37.5mg and gradually increased to where I am now which is 225mg.
Generally, I think Effexor has helped me with my depression and anxiety. I still have good days and bad days, but most are good. I've just been experiencing a side effect problem lately. It might not sound like much, but I'm having problems getting to sleep, I generally don't fall asleep until around 3-5 am, then once I'm asleep I have problems waking up. This is not good for me because I'm a student and these sleeping problems are causing me to miss classes. Just wondering if anyone else has had this problem and if they found a way to make it better.
Posted by jannbeau on November 26, 2002, at 17:25:20
In reply to Effexor Side Effects, posted by sarah w on November 26, 2002, at 17:11:28
> Hi, Sarah. The literature on Effexor suggests that problems of this nature may be rectified by changing the time of day when you take your medication.
Cheers,
Jannbeau
I've been on Effexor XR for about 8 months now, started off with 37.5mg and gradually increased to where I am now which is 225mg.
> Generally, I think Effexor has helped me with my depression and anxiety. I still have good days and bad days, but most are good. I've just been experiencing a side effect problem lately. It might not sound like much, but I'm having problems getting to sleep, I generally don't fall asleep until around 3-5 am, then once I'm asleep I have problems waking up. This is not good for me because I'm a student and these sleeping problems are causing me to miss classes. Just wondering if anyone else has had this problem and if they found a way to make it better.
Posted by johnlund on November 27, 2002, at 22:16:47
In reply to Re: Effexor and Effexor XR, posted by Badger on November 26, 2002, at 10:51:56
There is no difference between effexor and effexor XR except for the time release aspect. I believe XR uses a time release coating on the little beads of effexor. By the way, I think effexor is a great AD. I've been on it for three years.
Posted by Dan L on November 28, 2002, at 1:42:45
In reply to Re: withdrawing from effexor - angel girl-celexa, posted by lolly on March 21, 2002, at 19:25:16
I switched from effexor to celexa a few years ago. Celexa has been completely different from effexor for me (I was on effexor for about 6 months and have now been on Celexa for over 6 months). My social anxiety is pretty much gone, panic attacks are pretty much gone also. Celexa also gives me awesome vivid dreams too.
Posted by Dan L on November 28, 2002, at 1:51:51
In reply to Effexor XR? Successful but very ugly!, posted by Harry J on November 25, 2002, at 20:48:03
I had the same problem when I was on effexor. The psychosis was probably from the withdrawl syndrome since this medication has a very short half life and leaves the system quickly. If I missed doeses I would get very irritable and paranoid also with electric shock feelings.
Posted by Badger on November 28, 2002, at 8:16:08
In reply to Re: Effexor and Effexor XR, posted by johnlund on November 27, 2002, at 22:16:47
> There is no difference between effexor and effexor XR except for the time release aspect. I believe XR uses a time release coating on the little beads of effexor. By the way, I think effexor is a great AD. I've been on it for three years.
--
Thanks for replying. I was wondering if the longer half life of the XR version might mean less sensitivity to taking the drug at exactly the same time each day. I've been having mixed results in terms of sleeping since starting the medication 11 days ago, and have tried varying my evening dose by an hour or two earlier or later. I don't seem to have found the best time yet, but I really don't have enough experience yet to judge accurately (although overall I've been sleeping longer/better than before I started).I'm glad to hear that Effexor has worked well for you - this seems to be the overall consensus, even among those who have experienced bad side effects or withdrawal problems. I haven't noticed any consistent improvement yet, but I suspect that may just require a bit more time and finding the optimum dosage.
Posted by emerald may on December 2, 2002, at 3:22:24
In reply to Re: Permanently damaged!!!!!!!!!, posted by Lynn V on February 11, 2001, at 0:19:23
> Has anyone heard of myalgic (fibromyalgia) starting AFTER taking Effexor? Or if you did have fibromyalgia before, did it get worse with Effexor?
my mom has had fibromyalgia for about 3 years, and just recently started taking effexor. I have been taking effexor for about a year, and I have been having some odd symptoms recently, that were not previously there. I am making an appointment with my moms dr (the one in marina del rey) to see if I have it too. I am really nervous about having to ween myself from effexor, whenever that may be!
Posted by begtag on December 2, 2002, at 8:17:44
In reply to Re: Long-term effects, posted by stjames on July 8, 2000, at 23:15:07
Hello,
I am new to this message board. I suffer from anxiety attacks, panic attacks, and depression. I have been on Effexor for almost three years. I started to have health problems for the last year or so. Sorry to be graphic, but rectal bleeding, vomiting blood, chest pains, pelvic pains, breathing problems (like asthma attacks), liver problems, and several other problems. Because I have a history of uterine cancer, my doctor was very concerned. They sent me to specialist after specialist, with every invasive test imaginable. No one could find any cause for my bleeding. I asked my doctor several times, if it could be the medication. Effexor was the only medication I was taking. I then developed ovarian cysts.
Long story condensed here, I was roaming the web and came across this site about Effexor XR Side Effects. Imagine my shock and fear. I printed out all the information, which is also found in the free sample packs that your doctor supplies, and took it to my doctor. He was shocked. I am now, under his supervision, cutting down on my dosages, and hope to be effexor free in two weeks.
I know medications work different for everyone, and my intention is not to scare anyone away from taking the Effexor. It really did help me manage my depression and attacks. The nasty side effects I mentioned that happened to me were very rare. Just my luck. <g>
But after this disaster, I have requested that I try going drug free to see if I can deal with my depression. I am really scared to try another medication after this. Does anyone have any suggestions or ideas?
Thanks for listening,
Bonnie
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