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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 201 to 225 of 479. Go back in thread:
Posted by Jill on September 15, 2002, at 22:24:45
In reply to Jill---Re: General Remeron Questions, posted by McPac on September 15, 2002, at 21:46:23
No, I don't have increased agitation...just feel normal. However, I'm kind of natural high energy (when I'm not depressed) person. My doctor said that many can feel anxious or wired at 45mg or above. I just feel good and happy.
For me, personally, I am falling asleep and crying if I only take 30 mg. However, that's just my body chemistry. As a nice side note, my pdoc said that weight gain tends to be less at 30mg and above.
Oh, I do grind my teeth at night with my current dose (and have no way of knowing if I would at lower doses...but I might), but I wear a mouth guard and it's no big deal. I was embarrassed at first, but taking another medication to reduce that effect (I forget the name) made me feel headachey and yucky. My boyfriend is really cool about reminding me to put it in at night...it's a small price to pay for feeling so great.
Good luck with Remeron. You may find that a lower dose works right for you. (My sister, coincidentally, takes 45 mg too and feels sleepy and not as good on 30 mg. Must be a family chemistry thing).
Take care.
Jill
Posted by LyndaK on September 15, 2002, at 22:53:06
In reply to Re: Jill---Re: General Remeron Questions, posted by Jill on September 15, 2002, at 22:24:45
I'm currently on 45mg of Remeron, but over the past couple months have been feeling my anxiety level increasing and having difficulty sleeping. I've been thinking that the Remeron has been "pooping out" a bit. Tried increasing the dose slightly by breaking another pill (difficult to do without completely pulverizing it). Seems to have helped some. I see my pdoc on Wednesday. Another thing that's been happening is my eye keeps twitching a lot -- drives me crazy!! Muscle twitches were a common side-effect of the SSRI drugs -- haven't had it happen with the Remeron until recently. I'm on no other drugs.
Any thoughts or similar experiences?
Lynda
Posted by BarbaraCat on September 16, 2002, at 1:51:35
In reply to Re: General Remeron Questions, posted by McPac on September 15, 2002, at 17:14:38
Hi Mc,
Let's see if I can remember just how I was feeling. I remember that at 45mg I was feeling lethargic and wanted more zip and I also wanted to just test the waters and see how a higher dose felt. I went from 45 to almost 90 in about 3 weeks and definitely felt speedier, but not in a bad way. I was concerned that I was getting a little hypomanic which is not a bad thing in and of itself, but I tend to really wear myself out and crash. So I went down to 75mg and was feeling pretty good for about 1 month. Had alot of energy, motivation, just felt good. About 1 month ago I started feeling the blahs return and a flare up of my fibromyalgia symptoms (aching muscles, tiredness). I increased my thyroid during this time and felt the fibro symptoms and tiredness abate. Lately I've been feeling increasingly anxious and teetering on the verge of depression, tendency to cry easily, worry, etc. I think the increased thyroid is contributing to the anxiety and so reduced it. I know the thyroid has messed up the controlled study parameters, so to speak, but I also know that the Rem pooped out well before this. I also continued to gain weight no matter what, so now I'm down to 15 mg Rem and riding the rollercoaster. Benzos have helped alot during this time, but when I miss a dose I really feel it and believe I'm developing tolerance.I'm pretty fed up with antidepressants and our mis-managed health care system where pdocs have just enough time to whip out their prescription pads. I'm seeing a naturopath for some intensive nutritional chemo treatments and am hoping that my poor fried nervous system can heal. I'm feeling definitely anti-med right now. Nothing has ever worked for very long which probably means I have not stumbled yet upon the magic brew, but I fear my brain is getting harmed in the process, so I say fooey to Remeron and all the rest of the bunch.
The clinic you mention sounds very interesting and I will check it out, although I have no idea how to pay for such care. I certainly wish I were wealthy and could devote my time and money to just getting well and not have to compound things by worrying about - ugh - money.
> BarbaraCat
>
> Hi, Hope you are well.
> Question for you re: your Remeron experience:
>
> Did Remeron at higher doses MAKE you feel MORE anxious/agitated/nervous?
>
> It has for me (agitation/nerv./heart beating FASTER!
> I hate Remeron at these higher doses (45 mg for me).
> Perhaps if you did not feel these worsening symptoms it may be because you were on other meds (benzos) that counteracted these effects.
> Hey, one more question:
> Ever hear of the Pfeiffer Treatment Center (a nutritional care facility for biochemical imbalances)? I was thinking about going there; not sure yet. You can type its name and do a search to find it on the web.
> Take Care!
Posted by Roo on September 16, 2002, at 9:24:23
In reply to Re: General Remeron Questions » McPac, posted by BarbaraCat on September 16, 2002, at 1:51:35
Have you gained weight on Remeron?
Posted by BarbaraCat on September 16, 2002, at 12:39:30
In reply to Re: General Remeron Questions, posted by McPac on September 15, 2002, at 17:14:38
Hi Mc,
I checked out the Pfeiffer Center and it looks very interesting. I think a relative of my husband's went there with her son, who was diagnosed with ADD and slight autism. They discovered high levels of copper in his blood and put him on a regimen of customized vitamins and anti-copper compounds. It helped him tremendously. I also noticed that their prices are very reasonable with a Hope fund for those who can't pay the full price.The naturopath I'm going to has had me take numerous tests such as standard blood tests, live blood cell analysis (VERY fascinating), pH values, and hair analysis for heavy metals. The results aren't all in yet, but what has come back is showing some definite metabolic and cellular dysfunction. He's also an expert in hormones and how a dysfunction in any of those systems can cause havoc with psychological health. So I'm gettting intravenous vitamin and mineral drips until he can sort the whole interrelated mess out. I'm devouring endocrinology and cellular biology textbooks in the meantime to shed some light on the incredible complexity of our mortal coils. So at any rate, I'm probably getting the equivalent of the Pfeiffer Center and encourage you to explore this path. It makes sense to look at the whole body instead of only the brain.
Posted by Roo on September 16, 2002, at 14:20:28
In reply to Re: General Remeron Questions » McPac, posted by BarbaraCat on September 16, 2002, at 12:39:30
Please keep posting about these alternative methods
and how you're doing. I read about the Pffeifer Institute
and others like it and became interested in orthomolecular medicine too.
I've been off meds for a month and I'm trying acupuncture and homeopathy...
I like to go to some sort of Naturopath like you, Barbara Cat, one that
does all that testing...I would find it fascinating as well.
I know that this isn't a popular opinion around here, but I just feel
sure there has GOT to be some other way to treat depression other than these
meds. There's just got to be. Please, both of you, keep me updated...
I'll do the same...
Posted by BarbaraCat on September 16, 2002, at 15:05:09
In reply to Re: General Remero--McPhat and Barbara Cat, posted by Roo on September 16, 2002, at 14:20:28
Roo,
Good luck to you - you've got my total support on this. I think it's helping alot. If nothing else, I'll be a very fit and healthy mentally ill person. I'll ask my naturopath whom I'll be seeing on Friday his ideas on your finding a good doc. I'm reading a fascinating book about hormones and their role in physical and mental health (can't really separate them) that might be of interest to you. It's called 'Screaming to be Heard: Hormone connections women suspect and doctors still ignore" by Elizabeth Vliet, MD (newest edition). It's not so much 'alternative medicine' as a very thorough and enlightening endocrine study. I suspect you're a women? This will be extremely relevant. If not, it's still info that applies to everyone in ways most of us (including docs) are relatively clueless about. It will arm you with needed info you can take to your holistic doc when you find one.
Posted by Jill on September 16, 2002, at 16:53:18
In reply to Re: Jill---Re: General Remeron Questions, posted by LyndaK on September 15, 2002, at 22:53:06
In my experience (I've taken this drug for over 5 years), increasing the Remeron may actually be increasing the anxiety/twitching. I don't think your increased anxiety is necessarily Remeron poop out. In fact, my pdoc mentioned Remeron has less poop out than the SSRIs.
Talk to your doctor about possibly taking LESS for a short time (I take about 1/2 of my dose for about 4 days or so every few months to improve my sleep...then I go back up...and then sleep great again and feel great).
As a side note, don't forgot you and your doctor can be creative with dosing. I was taking 37.5 mg for a while (30mg + 1/2 a 15mg). Another thing to consider is that this drug, although faster to kick in for many than the SSRIs also isn't "automatic"...meaning that if you take a lower dose for a short time it will take a little bit for the norepinephrine (spelling?) to lower a bit. For me it takes about 4-7 days to feel a difference. To save $...with doc's ok...[can you tell I have OCD :)] you can talk about taking a 1/2 dose or other reduced dose on whatever schedule you find works with your body (I hear the pill cutters work well).
At the higher dosages (e.g., 45+ or even 30 for some people), my doc said NE is more prevalent. At low doses (like 15mg) you get more of the histamine effect (more tired, sleepy). It's a funky drug that way. Serotonin is also in there somewhere :). Reducing your dose of Remeron actually makes you more tired...interesting.
This is nice to know, because with this knowledge, I've been able just to slightly tweak my dosage at times and avoid having to take sleeping meds and also have been able to avoid feeling overly anxious (beyond what seems to be normal job/family/life stress). For me, less is more when it comes to medication. Remeron is the only med I use to treat my depression/OCD. My body is very sensitive to change (as I've been told many people with mental health issues are), so I feel so blessed that this medication works so well for me (no headaches, nausea, sleep problems, or anorgasmia...plus I feel really good).
Talk to your doc to see if reducing for a short time to activate more of the histamine effect will help.
Another aside, I have gained some weight on Remeron (although some is due to no longer being 27!). I went from a size 8 to a 10. Not a big deal. I asked my doc if I should try taking 60 mg to reduce a bit of hunger. However, since that would increase my teeth grinding and make sleep more difficult, we decided not to do that. (In Europe, my pdoc said dosages can be as high as 90mg. Weight gain seems very minimal then, but I know that I would be way too wound up and sleepless at that dose.)
Hope this helps. Please talk to your pdoc. Every body is different.
Take care,
Jill
Posted by Jill on September 16, 2002, at 17:00:57
In reply to Re: General Remeron Questions--Jill, posted by Roo on September 16, 2002, at 9:24:23
Hi Roo,
Yes, I've gained some, but it's not a big deal (I went from a size 8 to size 10). Please see my other post today. My sister also went from a size 6 to a size 8, which she says she really doesn't mind because she feels so great.
My pdoc said young, skinny females tend to gain more than other people. However, he said average weight gain due to the drug (at 30+ mg) was 7 pounds.
I'm currently 15 pounds heavier than I was 5 years ago. However, I was pretty much a nervous wreck at that time who often couldn't eat due to nerves. Also, I get very depressed periodically and drop a lot of weight (about 20 pounds during one episode...was down to 119 which for my swimmer's build of 5' 5 1/2" was very thin). And, now I'm 33 and not 27 and can't eat whatever I want without gaining weight.
I weigh 150 lbs now, but I don't mind wearing a slightly larger size. This drug is a God-send for me, and I wish I could stay on it during pregnancy. However, since there isn't much info out there on this drug during pregnancy, I think I'll have to go back to SSRIs :(.
Take care, and talk to your pdoc too about your concerns.
Best wishes.
Jill
Posted by Jill on September 16, 2002, at 17:04:17
In reply to Re: General Remeron Questions--Jill, posted by Jill on September 16, 2002, at 17:00:57
Just a quick note...my last post was a bit confusing. I USED to get depressed periodically and lose a lot of weight, but since being on Remeron since 7/97, I haven't had any more episodes.
Hope this helps.
Jill
Posted by LyndaK on September 16, 2002, at 23:42:45
In reply to Re: Jill---Re: General Remeron Questions, posted by Jill on September 16, 2002, at 16:53:18
Posted by McPac on September 17, 2002, at 8:35:53
In reply to Re: Jill---Re: General Remeron Questions, posted by Jill on September 16, 2002, at 16:53:18
Jill,
I didn't know you had OCD as well---me too.
I'm trying to get established on Remeron for my OCD right now (trying to go off of Zoloft).
At what dose do you recall working for your ocd?
Was your ocd the 'obsessional thinking/thoughts' or the compulsions OR both?
I'm hoping that a lower dose of Remeron could work for me; who knows?
Gotta run now, but, we must talk some more!
Take care
Posted by Jill on September 17, 2002, at 12:23:24
In reply to JILL---Re: General Remeron Questions, posted by McPac on September 17, 2002, at 8:35:53
Mc Pac,
I'm just home quickly for lunch...just got engaged last night, so I'm in a bit of a fog :).I take 45mg for my OCD. My OCD is almost purely obsessive thinking. Was brought up Catholic and took the guilt stuff VERY seriously!
I feel great at 45mg. The histamine aspect of the drug has really calmed me too. My sister has a similar "worried" personality...and she takes 45mg of Remeron too and feels very good.
I used to become depressed because I was so obsessional...if you have OCD, I'm sure you understand.
I'll check in later...but I have to tell my sisters about my engagement before I run back to work!
Take good care :)
Jill
Posted by Roo on September 17, 2002, at 12:41:32
In reply to Re: JILL---Re: General Remeron Questions, posted by Jill on September 17, 2002, at 12:23:24
Posted by BarbaraCat on September 17, 2002, at 21:51:38
In reply to Re: JILL---Re: General Remeron Questions, posted by Jill on September 17, 2002, at 12:23:24
Hi Jill,
May you be wondrously happy. I hope your future hubby knows that he has a zillion babblers to answer to for treating you well! ;)BTW, I too am a recovering Catholic. I didn't associate my leftover guilt, worry, persnickediness to Catholism, but now that you mention it...
Posted by Roo on September 18, 2002, at 18:43:10
In reply to Re: Alternatives » Roo, posted by BarbaraCat on September 16, 2002, at 15:05:09
> Roo,
> Good luck to you - you've got my total support
on this. I think it's helping alot.So you're starting to feel a lot better? How long
did it take?If nothing
else, I'll be a very fit and healthy mentally
ill person. I'll ask my naturopath whom I'll be
seeing on Friday his ideas on your finding a
good doc.Thank you...I'd appreciate that...or has the appt. already
passed? If so, how did it go?
I'm reading a fascinating book about
hormones and their role in physical and mental
health (can't really separate them) that might
be of interest to you. It's called 'Screaming
to be Heard: Hormone connections women suspect
and doctors still ignore" by Elizabeth Vliet,
MD (newest edition). It's not so much
'alternative medicine' as a very thorough and
enlightening endocrine study. I suspect you're
a women? This will be extremely relevant.
I've wondered about hormonal stuff. I had a complete
endocrinology screening though, not too long ago, and
everything checked out normal. Yes, I'm a 34 year old
female. The book sounds interesting. Sometimes it
certainly FEELS hormonal...I'll get PMS like symptoms
(irritability, big time, almost like rage) only it won't
be PMS.
I'm actually feeling pretty discouraged at the moment...I
don't think the acupuncture is helping substantially...I'll
feel really good the day of my appt., but it doesn't last.
My next step is homeopathy...but I'm feeling despairing...I
don't know how much longer I can go feeling like shit...and this
stuff is SO expensive it's breaking me. I'm not sure what to
do. I loathe the thought of going back on conventional meds, but
if I have to, I will. I'm not going to live my life in misery.
Posted by BarbaraCat on September 18, 2002, at 20:24:58
In reply to Re: Alternatives--Barbara Cat, posted by Roo on September 18, 2002, at 18:43:10
If you feel like it's your hormones, there's a good chance it is. If you have PMS, you have a hormonal imbalance - it's really not normal to have PMS. That book is continuing to be an eyeopener. For instance, estrogen is neurotransmitter mediator. Too much progesterone doesn't allow cellular binding of serotonin, NE. Estrogen has a direct impact on the thyroid gland. When estrogen declines, (such as in the latter half of the cycle), serotonin goes way down. Estrogen also keeps in check the enzyme that destroys MAO, like on on-board MAOI. Even if the underlying problem isn't specifically reproductive hormones, it's likely to be hormonally related and besides it's fascinating info.
I had my appt yesterday and some of it's looking like a hypoglycemia problem, actually almost prediabetic. I'll be doing The Zone diet to bring my insulin/glucagon into balance and that should help alot. I did hours of researching last night on 'reactive hypoglycemia' and boy, there I was to a T. When blood sugar dips, there's a push to get that sugar to the brain and sending one into a fight/flight state thanks to a surge in NE does the trick. Problem is that the flood of cortisol from the adreniline wires up our autonomic stress system and it feel like constant anxiety and panic. Even my fibromyalgia-like symptoms made sense! Most primary care docs test only for glucose fasting hypoglycemia which isn't the same thing. And even if this isn't 'the answer', I'm learning an incredible amount of relevant stuff that all interrelates.
It probably goes back to the pituitary which just seems like it became fried at some point. My metabolic functions are compromised and tweaking one branch sends the other systems into imbalance. So, I'll be continuing with the vitamin/mineral IV drips and will be starting other therapies to target the hormonal imbalances, and it's only the beginning. So very ghastly expensive! We can't afford, but I'll clean toilets to pay for this because I really believe I'm on to something - my naturopath is filling in the gaps and providing the analysis, but I'm feeling like new roads are appearing and my energy is coming back to explore them.
I don't blame you for being discouraged. My thoughts on accupuncture, homeopathy and the enegy therapies are that if they're going to turn a long-standing ill system around, it will take a long time to bring about large changes. Once you're there, the change can be maintained. But if you have hormonal dysfunction going on, then I think you need more heavy hitting artillerary while still keeping the whole body approach. I think it's all worth it, Roo. I was getting so physically emotionally and spiritually sick that time was running out fast.
He didn't have any brainstorms as to how to find a good doctor. There is www.acam.org to search for a one. Another interesting one is:
http://www.digitalnaturopath.com/ There's an online health analysis, but also a list of naturopaths by state. Good luck, friend, and keep me posted. You might want to ask your acupuncturist.
Posted by Jill on September 18, 2002, at 21:43:40
In reply to Re: Congratulations!! » Jill, posted by BarbaraCat on September 17, 2002, at 21:51:38
Thanks so much for the kind words! I'm still a bit stunned by the engagement, but my fiance (how weird to type that!) and I are very happy, even though we admit it's a bit scary...good scary though!
Here's a very interesting article on Catholicism/OCD that I found a few months ago. It actually helped me to read it, because my symptoms started up around the time I had a very intense CCD teacher when I was 12 yrs. old. My symptoms eventually made going to mass very difficult and emotionally painful and included intense fear of harming people I loved...to the point I didn't want to take care of small children or go out with friends. Thankfully, with counseling, understanding of the condition, medication, and a sense of humor, my OCD is very manageable.
I got a good chuckle out of the line from a church "higher up" that said "I don't know anyone in the clergy who even exhibits any mild signs of OCD" (paraphrased...)
I laughed out loud...then what was I doing during all those Hail Marys and crossing my forehead, lips, and heart and repeating over and over "Lord Hear Our Prayer" ?
(No offence to any Catholics. My parents are very devout and I see positives in Catholicism too...I just personally found that line funny.)
Take care, and I hope you find this article helpful.
http://news.bbc.co.uk/1/hi/health/2014244.stm
Jill :)
Posted by McPac on September 18, 2002, at 22:41:40
In reply to OCD/Catholicism article, posted by Jill on September 18, 2002, at 21:43:40
Jill,
Do you take any other med besides the Remeron?
Also, how long did it take you before you felt 'fine' on the Remeron?
Lastly, congratulations to you on your engagement.
Posted by Jill on September 19, 2002, at 7:37:25
In reply to Jill Re: OCD/Catholicism article, posted by McPac on September 18, 2002, at 22:41:40
Thanks for the congratulations! I began feeling really good on Remeron about 1 month after starting (we started at 15 and then went to 30mg and finally 45mg in just a few weeks...I think I was on Remeron at 45mg when I really started feeling great).
I had been taking Prozac for a short time before Remeron...but I really felt better on Remeron. I've read (and found myself...so has my sister) that Remeron seems to "kick in" faster than the SSRIs.
Yes, I only take Remeron for my OCD/depression. I haven't had a major depressive episode in 5 1/2 years...since I began Remeron.
Hope this helps. Have a great day!
Jill
Posted by Roo on September 19, 2002, at 9:30:11
In reply to Re: Alternatives » Roo, posted by BarbaraCat on September 18, 2002, at 20:24:58
For instance, estrogen is
neurotransmitter mediator. Too much
progesterone doesn't allow cellular binding
of serotonin, NE. Estrogen has a direct impact
on the thyroid gland. When estrogen declines,
(such as in the latter half of the cycle),
serotonin goes way down. Estrogen also keeps
in check the enzyme that destroys MAO, like
on on-board MAOI. Even if the underlying problem
isn't specifically reproductive hormones, it's
likely to be hormonally related and besides it's
fascinating info.
Well what do you think about the fact that I got my hormones
tested and the tests showed "normal"? Do you think the conventional
testing is accurate? I know it has something to do with low seratonin,
b/c the SSRI's work well and fast for me, and the non-seratoningenic
drugs don't do much for me. I guess the question is WHY is it low--hormones,
vitamin deficiencies, ?? Do the naturopaths do blood work and testing?
I find that comforting somehow...the testing....it seems like something concrete
you can point to and say "yes--see here...you're low in b vitamins".>
> I had my appt yesterday and some of it's looking
like a hypoglycemia problem, actually almost
prediabetic. I'll be doing The Zone diet to
bring my insulin/glucagon into balance and that
should help alot. I did hours of researching
last night on 'reactive hypoglycemia' and boy,
That's interesting. I know I definitely am hypoglycemic.
And horribly addicted to sugar! I know I use sugar and carbs
to self medicate.
So very ghastly expensive! We can't afford
, but I'll clean toilets to pay for this because
I really believe I'm on to something -
my naturopath is filling in the gaps and
providing the analysis, but I'm feeling
like new roads are appearing and my energy
is coming back to explore them.
I'm happy for you, but also a little jealous. I feel like success is
for everyone else but me in these matters--I've seen so many people
recover without drugs or be able to take them for the requisite 6 months
and be recovered. I feel screwed. I'm sure that's my depression talking,
but you kind of need a positive attitude to get through this stuff, and
I just don't have it. I'm definitely despairing. I just
don't know if I can make it and I feel so shitty about that.
I'm just feeling too bad (and have been really bad, like
suicidal thoughts and all that) for the past 5 months. I'd
like to be able to tough it out and give these things time,
but, damn. The acupuncturist actually told me if you're not
getting substantial relief after a month, it's probably not going
to work. And she's tops in her field--very, very qualified.
I'm so frustrated. I wish some fairy godmother would just appear and
help me out with all this, but that aint gonna happen.>
But if you have hormonal
dysfunction going on, then I think you need
more heavy hitting artillerary while still
keeping the whole body approach. I think it's
all worth it, Roo. I was getting so physically
emotionally and spiritually sick that time was
running out fast.
Not sure how to figure out the hormonal stuff...especially
since I've already had them tested by an endocrinologist and
they came out normal. Maybe I should just take an estrogen
heavy BC pill and see if it makes me feel better. I remember
being on the pill a LONG time ago, and it made my depression
worse. It was a low dose pill.I don't know, B. Cat. How long did it take you before you
started feeling mentally better?Those sites were interesting--thanks. I might do the
digital naturopath report. Did you get one? Was it helpful?
Might be a good thing to bring to a naturopath.Thanks, and sorry for the whining. I just feel like I'm banging
my head against a brick wall and needed to vent.
>
Posted by Roo on September 19, 2002, at 14:21:03
In reply to Re: Alternatives, posted by Roo on September 19, 2002, at 9:30:11
I don't know if this is hormonal or what's happening....
but the last two weeks I feel like I'm pregnant or something
(which is totally impossible)...I'm nauseous, nothing tastes right
or good, certain smells or tastes make me want to puke, my breasts
are sore. My G.I. track is totally screwed up and has been since
zoloft messed it up a couple of months ago (I was only on it for a month
and quit for G.I. reasons, but it's never been the same since...now I
feel like I have IBS or something. I feel like I'm turning into a hypochondriac.
And I don't know what's happening.
Don't know if you would have any insight into that at all, but thought
I'd give it a shot.
Posted by McPac on September 19, 2002, at 14:41:56
In reply to Re: Jill Re: OCD/Catholicism article, posted by Jill on September 19, 2002, at 7:37:25
Jill, thank you for your information. It was VERY much appreciated.
Posted by McPac on September 19, 2002, at 14:45:34
In reply to Re: Alternatives, posted by Roo on September 19, 2002, at 9:30:11
Roo "That's interesting. I know I definitely am hypoglycemic.
And horribly addicted to sugar! I know I use sugar and carbs
to self medicate.">>>>>>>>Try to lay off the sugar Roo...it's a definite "no-no".
Don't feel bad about needing the meds Roo....I know that I have to have them. I may, possibly, be going to the Pfeiffer Treatment Center...will report back if I do decide to go there.
Posted by BarbaraCat on September 19, 2002, at 14:54:03
In reply to Re: Alternatives, posted by Roo on September 19, 2002, at 9:30:11
Your question of why is serotonin low is the question of the decade. If we could figure that one out, there would be a race to patent it. The reproductive and other hormones certainly play a big part in it, but it leads back to where did they go out of whack in the first place. Alot of theories about toxins in our environment acting as neuro-modulators and hormonal disruptors. You asked about testing and that also is a very controversial subject. Hormones ebb and flow, especially in a menstruating woman, so blood work should be done at least twice during the month. What the tests measure is the serum, or blood levels of circulating hormones, however, they don't measure how and if the hormones are binding efficiently on a cellular level. Many substances are molecular mimickers of hormones and fit in the receptor site enough to block the real hormones from binding, but the fit isn't close enough to signal the cell's response. So you can have plenty of hormones circulating in the blood serum, whether estrogen, progestin, thyroid, androgens, insulin, glucagon, whatever, but if they're not able to effect a cellular response, it's like starving in the midst of plenty. The pituitary is the master gland in all this, so it's likely that this is where it begins. That's good news, but it doesn't help since there isn't a way to 'fix' a dysfunctional pituitary that anyone knows about at this time.
One thing that stands out is the fact that you have PMS and had bad reactions to birth control pills. Both are high progesterone states. Progesterone in exess can block estrodiol and estrodiol is needed for serotonin synthesis. This isn't to say that you simply gobble estrogen pills either. I think that's the standard medical approach which works in the short run but doesn't address the underlying dysfunction. But your endocrine tests may simply be telling a true picture and something else is going on.
Roo, the fact that you said you're a sugar and carb self medicator is the red flag. It sounds like 'reactive' rather than 'glucose fasting' hypoglycemia. If this is so, it's a huge piece in the puzzle of why you're feeling bad. This is the piece of the puzzle that's fitting for me. I've been following a version of The Zone diet just recently and it's been pretty amazing in how better I feel. If you suspect you have a condition linked to low blood sugar and the resultant insulin spikes then a good nutritionally oriented doctor or practitioner who REALLY knows what they're doing is the first step. Really, when you think of it, we have no control over anything in our lives except what we put into our bodies. Eating a high carbo and sugar diet is the first place to look and start finding ways to control it. It's not easy cause it becomes like a drug.
You say you don't want to go back to ADs. Perhaps as a stop gap until other systems get under control? You asked how long it took. It's been about 1 month since I started seeing him and getting intense treatments. I'm down to 7 mg of Remeron and have reduced the other meds considerably. I'm feeling alot better, but keeping my fingers crossed. Oh well, I'll take what I can get - a few good days now is better than the constant misery of before.
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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
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