Psycho-Babble Medication Thread 75408

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Re: hypertensive experiences? » may-b

Posted by jsarirose on July 20, 2002, at 13:49:58

In reply to Re: hypertensive experiences? » LLL, posted by may-b on July 20, 2002, at 11:43:51

> > Regarding hypertensive crisis and it being >rare - I consumed a small piece of teriyaki >chicken breast and had a "ride to hell" as a >result. Not only did I require a trip via >ambulance to the ER, I was subjected to >terrible care by personnel who kept asking in >unsympathetic fashion "why did you try to kill >yourself"?
>
> I had a similar experience -- disrespectful ER 'care' and the same offensive question. The idea that I would have to deal with more unenlightened medical personnel has scared me away from using Parnate, the only AD that has actually helped.
>
> Best wishes,
> may-b

May-b: I hate to see you avoid a potentially positive drug because of the ignorant out there. It is a lifesaver for me as well. I do find I need to periodically educate pharmacists (luckily I have a good psychiatrist). I have never had to go to the emergency room because of a hypertensive crisis however, and I've had three. All doctors should be required to prescribe some sort of "emergency" pill. I'm shocked at the number that don't and refer people to the emergency room if in crisis.

I take Chlorpromazine (Thorazine) for at attack. It works great, I just take one pill, and the best part is that if I'm not actually having a blood pressure spike it won't hurt me. The first two attacks, the doctor's on call asked what my blood pressure was. Of course I had no idea as I wa at home! Then my doctor told me it was safe to take if I thought I was in crisis as it won't bring my blood pressure too low if it's not elevated.

I highly recommend giving Parnate another try if you are still searching for something. Just make sure you have some sort of crisis pill. And I think a home blood pressure kit is a great idea.

-Jessica

 

Re: hypertensive experiences? » cybercafe

Posted by jsarirose on July 20, 2002, at 13:55:18

In reply to Re: hypertensive experiences?, posted by cybercafe on July 20, 2002, at 11:38:27

I've started augmenting the Parnate with Lamictal. I was on it once before by itself (the Lamictal) but we only went up to 400mg. After I got off, my doctor consulted with someone else who recommended pushing it much higher - up to 800mg if necessary. At that time we didn't. Now that Parnate is working well, we're slowly tapering down the Parnate and up the Lamictal. We'll go up to 600-800mg if necessary. It may be that a balance of Parnate and Lamictal is necessary, or if I'm lucky, I'll be able to go off Parnate and just be on Lamictal eventually.

I'm doing it very slowly as I absolutely don't want to lose the positive effects of Parnate and any gains I've had in my depression.

Something to think about!

-Jessica
(Treatment Resistant Depression often requires very high doses of meds, most can go higher than the pharmaceutical companies originally state.)

 

Re: hypertensive experiences? » cybercafe

Posted by jsarirose on July 20, 2002, at 14:27:41

In reply to Re: hypertensive experiences?, posted by cybercafe on July 20, 2002, at 5:00:04

> Actually my doc says it's pretty much impossible for me to have a hypertensive crisis... and if I do, it will be mild and I should just be able to take some ibuprofen or acetaminofin or something....
>
> ... and my doc is by far one of the most knowledgable docs i have ever seen, so i am quite prone to believe him -- though yes, i would feel much better with some nifedepine (Adalat??) ...
>
> (it's too bad... my father just stopped taking the drug and used up his last pill)

Why does he say that? I've never heard of that? Does that mean you don't have to follow the diet? If you do have to follow the diet - why? If there is no danger of a hypertensive crisis (according to your doctor) why would you need to watch what you eat?

Sorry - don't mean to sound accusatory, I'm just baffled by the reasoning. Also, I've had severe migraine (a common effect) without have elevated blood pressure from something I ate while on Parnate. The Thorazine greatly helped the migraine. I'm wondering if while you may not be endangering your heart/life if you are still prone to a tyramine migraine.

-Jessica

 

Re: hypertensive experiences? » cybercafe

Posted by LLL on July 20, 2002, at 14:53:54

In reply to Re: hypertensive experiences?, posted by cybercafe on July 20, 2002, at 5:00:04

Re: My doctor says I won't have a hypertensive crisis - suggestion - get a new doc!
He/she's obviously never had one. It's not just the rise in B/P (which doesn't have to go very high) but also the terrible head pain and all the fear that goes with knowing you might have precipitated a cranial bleed. Think about it.

 

Re: hypertensive experiences? » jsarirose

Posted by may-b on July 20, 2002, at 16:44:33

In reply to Re: hypertensive experiences? » may-b, posted by jsarirose on July 20, 2002, at 13:49:58

Hi Jessica

Thanks! I will ask the doctor about Thorazine. (I really enjoy your posts.)

best wishes,
may-b

 

Re: hypertensive experiences? » may-b

Posted by jsarirose on July 20, 2002, at 21:14:30

In reply to Re: hypertensive experiences? » jsarirose, posted by may-b on July 20, 2002, at 16:44:33

> Hi Jessica
>
> Thanks! I will ask the doctor about Thorazine. (I really enjoy your posts.)
>
> best wishes,
> may-b

Well, there is so much in life that I know nothing about. I've been through the anti-depression med gamut for so many years that when I actually know something I love nothing more than telling anyone that will listen! As always, imho.

-Jessica

 

Re: hypertensive experiences?

Posted by cybercafe on July 21, 2002, at 1:06:12

In reply to Re: hypertensive experiences? » cybercafe, posted by jsarirose on July 20, 2002, at 14:27:41

> Why does he say that? I've never heard of that? Does that mean you don't have to follow the diet? If you do have to follow the diet - why? If there is no danger of a hypertensive crisis (according to your doctor) why would you need to watch what you eat?

the only things i can't have are soy sauce, marmite, broad beans and alcohol (he says not to take alcohol with any drug cuz it does not allow the drug to be metabolized which makes good sense to me) ....


basically i got the feeling that if i ate any of those foods i would have a mild headache... i don't particularly want any kind of headache...

i suppose i do fear getting a migraine or worse .. even if there's only a 0.1% chance, i still wouldn't want to risk it...


> Sorry - don't mean to sound accusatory, I'm just baffled by the reasoning. Also, I've had severe migraine (a common effect) without have elevated blood pressure from something I ate while on Parnate. The Thorazine greatly helped the migraine. I'm wondering if while you may not be endangering your heart/life if you are still prone to a tyramine migraine.

hey no prob i don't take it as anything but genuine curiousity :)
- remember, as a victim of ignorant and unavailable docs, my first instinct is to bombard people with questions too - it's tough to have to treat yourself :)

... okay let me ask you a question.... how bad is a tyramine migraine, like what does it feel like, and can you just take regular aspirin for it?

 

Re: hypertensive experiences?

Posted by cybercafe on July 21, 2002, at 1:10:30

In reply to Re: hypertensive experiences? » cybercafe, posted by LLL on July 20, 2002, at 14:53:54

> Re: My doctor says I won't have a hypertensive crisis - suggestion - get a new doc!
> He/she's obviously never had one. It's not just the rise in B/P (which doesn't have to go very high) but also the terrible head pain and all the fear that goes with knowing you might have precipitated a cranial bleed. Think about it.

... see my message to jess... re: what does it feel like, and does regular aspirin work?

... and is hypertensive crisis a factor of age, gender, weight? .. as i am young, male, and probably underweight :) ....

... as for my pdoc... he is really really good... i totally respect him... though we disagree from time to time... unlike other docs, he can actually back up what he says with good reason...

... next time i go in i will ask why i am any different than the other fellows here i have talked to who have had hypertensive crisis

 

Re: hypertensive experiences? » cybercafe

Posted by jsarirose on July 21, 2002, at 1:34:01

In reply to Re: hypertensive experiences?, posted by cybercafe on July 21, 2002, at 1:10:30

> > Re: My doctor says I won't have a hypertensive crisis - suggestion - get a new doc!
> > He/she's obviously never had one. It's not just the rise in B/P (which doesn't have to go very high) but also the terrible head pain and all the fear that goes with knowing you might have precipitated a cranial bleed. Think about it.
>
> ... see my message to jess... re: what does it feel like, and does regular aspirin work?
>
> ... and is hypertensive crisis a factor of age, gender, weight? .. as i am young, male, and probably underweight :) ....
>
> ... as for my pdoc... he is really really good... i totally respect him... though we disagree from time to time... unlike other docs, he can actually back up what he says with good reason...
>
> ... next time i go in i will ask why i am any different than the other fellows here i have talked to who have had hypertensive crisis

It's absolutely nothing like a bad headache. It's far worse and regular meds like aspirin, ibuprofen and Aleve don't do much. It begins as a pounding on the side of the head. The pain is so intense I've actually cried. Then eventually the specific point of pain will start to spread out. It spread toward the front/top of my head and eventually I have a migraine throughtout. Migraines have certain characteristics like nausea, sensitivity to light and sound, some people see auras as well. You may or may not have all of these symptoms. It's also characterized by "a moderate to severe throbbing pain for four to 72 hours that is frequently on one side of the head".

If you're on an MAOI and you ingest too much tyramine it can bring on a migraine. It has nothing to do with your sex, weight, age, health, etc. It's strictly the tyramine interacting with the med.

I'm guessing your doctor knows something we don't about your dosage. (Aren't you taking just 30mg?) I've just never heard of not having to watch your diet. Do you eat cheese, like cheddar, too? If you can eat aged cheeses with no effect then it sounds like your doctor is right. They have one of the highest tyramine levels.

Here's a 'read'-bite I found: "Because the sequela from tyramine and MAOIs is dose-related, reactions can be minimized without total abstinence from tyramine-containing foods. Approximately 10 to 25 mg of tyramine is required for a severe reaction compared to 6 to 10 mg for a mild reaction."

Sounds like it is dose related.

-Jessica

 

Re: hypertensive experiences?

Posted by cybercafe on July 21, 2002, at 2:46:44

In reply to Re: hypertensive experiences? » cybercafe, posted by jsarirose on July 21, 2002, at 1:34:01

> It's absolutely nothing like a bad headache. It's far worse and regular meds like aspirin, ibuprofen and Aleve don't do much. It begins as a pounding on the side of the head. The pain is so intense I've actually cried. Then eventually the specific point of pain will start to spread out. It spread toward the front/top of my head

I really appreciate the info Jess -- I would have been in big trouble if I had to find out that over-the-counter meds didn't work on my own ! Ouch !

 

Re: hypertensive experiences?

Posted by LLL on July 21, 2002, at 9:25:58

In reply to Re: hypertensive experiences?, posted by cybercafe on July 21, 2002, at 2:46:44

> > It's absolutely nothing like a bad headache. It's far worse and regular meds like aspirin, ibuprofen and Aleve don't do much. It begins as a pounding on the side of the head. The pain is so intense I've actually cried. Then eventually the specific point of pain will start to spread out. It spread toward the front/top of my head
>
> I really appreciate the info Jess -- I would have been in big trouble if I had to find out that over-the-counter meds didn't work on my own ! Ouch !
>
>It's NOTHING like a regular headache. Although I strongly believe in the positive benefits of taking Parnate I am currently scared to death of triggering a hypertensive crisis after experiencing two. As Jess said, height,weight and gender do not matter. 30 mg of Parnate is not a "low" dose. Please educated yourself and what happens during a tyramine reaction and learn from other's mistakes. It was one of the most painful and scariest experiences of my life. The first time I was working as a psychotherapist(now retired)in a hospital psychiatric unit, side by side with my psychiatrist and team of nurses/therapists/friends. The second time as I mentioned before, was complete with paramedics, an ambulance ride, and lousy, humiliating hospital care. Each time I used Procardia sublingualy and although can decrease blood pressure - it did nothing to stop the pain (which is like an explosion, gun shot through your head) or ease my fear. Thorazine is used as an antedote as well. Hypertensive crisis may include stroke, intracerebral bleeding, cardiac failure and death. Your age has nothing to do with it! You may need to educate your doctor as most of us have. My former very knowledgeable, very much trusted, loved and respected, "Harvard educated" psychiatrist, friend, and colleague switched me from Nardil to Parnate too quickly. I was the one who warned her against doing so and told her what the literature recommended. She instead instructed me differently and precipitated my first hypertensive crisis! This was both a humbling and learning experience for her as well!
She is now much more cautious and conservative in her recommendations. However, since she is now over 1,000 miles away I unfortunately cannot use her as my physician.
I am disturbed by some of the prior postings which report a somewhat cavalier attitude toward their diet. I suggest you err on the side of caution and go with what research supports.
I wouldn't be on Parnate again however, if I didn't think the benefits were worth it and I am one of those few who cannot take anything else.
Hope this helps.
Good Luck,
Lisa

 

Re: hypertensive experiences?

Posted by cybercafe on July 21, 2002, at 12:55:45

In reply to Re: hypertensive experiences?, posted by LLL on July 21, 2002, at 9:25:58

>hospital care. Each time I used Procardia sublingualy and although can decrease blood pressure - it did nothing to stop the pain (which is like an explosion, gun shot through your head)

... nifedepine doesn't get rid of the pain?

what can you take to get rid of the pain then? ....

oh and if you have the pain with no rise in blood pressure is it worth taking the nifedepine at all?


thanks a lot for the info guys ... i'm going to see my doc tomorrow but i'm still a little confused what to be satisfied with

 

Re: hypertensive experiences?

Posted by jsarirose on July 21, 2002, at 15:07:36

In reply to Re: hypertensive experiences?, posted by cybercafe on July 21, 2002, at 12:55:45

> >hospital care. Each time I used Procardia sublingualy and although can decrease blood pressure - it did nothing to stop the pain (which is like an explosion, gun shot through your head)
>
> ... nifedepine doesn't get rid of the pain?
>
> what can you take to get rid of the pain then? ....
>
> oh and if you have the pain with no rise in blood pressure is it worth taking the nifedepine at all?
>
>
> thanks a lot for the info guys ... i'm going to see my doc tomorrow but i'm still a little confused what to be satisfied with

I don't know about nifedepine, but Thorazine seems to help deal with the pain for me. I've taken a pain pill (oxycodone) with and without the Thorazine when I had an attack and the Thorazine definitely helped me feel at least tolerable sooner. It also really wiped me out (but I'd prefer having to sleep for a day or two than deal with the pain a minute longer than necessary). It will also help lower blood pressure if that is part of the problem.

You may want to ask you doctor about that one as well. Especially since it's safe to take whether your blood pressure is elevated or not.

-Jessica
(Pick mine, pick mine! Just kidding')

 

Re: MAOI diet short list » Elizabeth

Posted by Sparkie416 on July 21, 2002, at 16:30:58

In reply to MAOI diet short list, posted by Elizabeth on August 17, 2001, at 13:43:12

> Hi. A couple of people have requested that I repost the dietary restrictions that I followed while taking MAOIs. Please don't take this as gospel; it's what worked for me and it's based on some fairly meticulous library research (I can provide a reading list for anyone who's interested). A lot of the "menus" that get handed out by pharmacies, hostpials, doctors, etc. are not very accurate because they are out of date and place extreme and unnecessary restrictions on what you can eat. This results in a number of problems. Many people are scared off by long, intimidating lists of restrictions. In other cases, a person will discover that s/he can "cheat" on some of the foods (the ones that really shouldn't be on the list) and will therefore take the entire list less seriously. There are some things that you definitely should avoid, but they are relatively few.
>
> So, here it is -- a list of some things that I felt merited avoidance, and others that I felt were safe (and had no problems with, of course):
>
> WINE is fine. Some people may get histamine-related headaches from it and think they are having a hypertensive episode when they are not.
>
> BOTTLED BEERS are usually fine (American and Canadian ones are the best studied).
>
> TAP BEER should be avoided.
>
> Most AGED CHEESES are out. Of note, the mozzarella generally used on most pizzas has been found to be okay. So unless it's some weird exotic pizza with sharp cheeses (feta, cheddar, fontina) it should be okay to eat pizza. (In general, cheeses described as "sharp" are the most dangerous ones.) Ricotta cheese, cottage cheese, cream cheese, and "pasteurized process cheese food" (American cheese -- the cheesiest kind) are okay as well. In regard to the intermediately-aged cheeses, I personally had no problem with jack or brie in moderation. I would be careful if you're going to try this, though, and it's not something I'm willing to say is definitely safe.
>
> OTHER DAIRY PRODUCTS, such as milk, yogurt, and sour cream, are generally safe as long as they are fresh.
>
> SOY FOODS are controversial: one sample of soy sauce was reported to have quite a lot of tyramine in it, but there aren't any documented interactions. My experience has been that a little bit of soy sauce is okay. I would avoid other soy products, such as soy milk and tofu. The Taiwanese dish called "stinky tofu" is probably right out. < g >
>
> Similarly, SAUERKRAUT has been found to contain a large amount of tyramine in some analyses, but there aren't any reactions documented that were associated with sauerkraut.
>
> PROTEIN-CONTAINING FOODS that have passed the expiration date or that may have been stored improperly should be avoided. Fresh milk, meat, etc. are okay. One exception that I make, just because there have been so many problems reported with it, is LIVER; it seems possible that the proteins in liver are especially readily broken down to tyramine (perhaps they include more tyrosine than other proteins do, or perhaps the bacteria that turn tyrosine into tyramine are fond of liver).
>
> Certain AGED MEATS, such as salami, bologna, and some sausages, may be problematic. Err on the side of caution. Some telltale words to look for are "aged," "smoked," "air-dried," and "fermented."
>
> PICKLED HERRING itself isn't a problem, just don't eat the brine (yuck!).
>
> To many people's relief, CHOCOLATE is fine. (If my experience with carb cravings on phenelzine is any indication, it's fine in *huge* amounts!)
>
> Some miscellaneous peculiar foods, such as FAVA BEAN PODS and BANANA PEELS, also cause problems. Shouldn't be a major issue for most people. Watch out for Middle Eastern cuisine, which sometimes contains fava beans. MISO SOUP and other Oriental soup stocks have also been reported to cause problems.
>
> I hope that people find this helpful. As I said, I can provide a list of references if anyone is interested.
>
> -elizabeth

Elizabeth,
Please list the references. I would be interested in reading them
Thanks.
Sparkie

 

Re: hypertensive experiences?

Posted by LLL on July 21, 2002, at 17:37:20

In reply to Re: hypertensive experiences?, posted by cybercafe on July 21, 2002, at 12:55:45

It takes an hour or two or more for the pain to subside. If you're in the ER you're being given I.V. med's at the time.

 

Re: MAOI diet short list » Sparkie416

Posted by LLL on July 21, 2002, at 17:54:54

In reply to Re: MAOI diet short list » Elizabeth, posted by Sparkie416 on July 21, 2002, at 16:30:58

I'm still confused! I don't remember before avoiding frozen dinners (except those in cheese sauces) and now am having to eliminate these because they contain "yeast" or "autolyzed yeast extract". Can someone out there provide documentation confirming that in fact name brand frozen food products containing the above are prohibited?
Also, I went on line to read "The Making of a user Friendly MAOI Diet" in the Journal of Clinical Psychiatry, 1996:57(3):99-104 and there is nothing accessable prior to October of that year. How can I get a copy?
Thanks
Lisa

 

Re: MAOI diet short list

Posted by jsarirose on July 22, 2002, at 2:52:50

In reply to Re: MAOI diet short list » Elizabeth, posted by Sparkie416 on July 21, 2002, at 16:30:58

To add to the list - remember any pastes are not allowed at all! For example fish paste & anchovy paste. May sound like something you'd never eat, but they actually use some of those pastes in some of the Asian soups. I was sick from some Vietnamese Pho which I found out contains anchovy paste.

Be careful out there,
Jessica

 

Re: MAOI diet short list

Posted by cybercafe on July 22, 2002, at 2:56:24

In reply to Re: MAOI diet short list, posted by jsarirose on July 22, 2002, at 2:52:50

> To add to the list - remember any pastes are not allowed at all! For example fish paste & anchovy paste. May sound like something you'd never eat, but they actually use some of those pastes in some of the Asian soups. I was sick from some Vietnamese Pho which I found out contains anchovy paste.

really? my mom keeps trying to push the paste on me...

jess you have saved my butt yet again ...

... i am going to have to recommend you charge my health care insurance $500

 

Re: MAOI diet short list » LLL

Posted by jsarirose on July 22, 2002, at 3:02:33

In reply to Re: MAOI diet short list » Sparkie416, posted by LLL on July 21, 2002, at 17:54:54

> I'm still confused! I don't remember before avoiding frozen dinners (except those in cheese sauces) and now am having to eliminate these because they contain "yeast" or "autolyzed yeast extract". Can someone out there provide documentation confirming that in fact name brand frozen food products containing the above are prohibited?
> Also, I went on line to read "The Making of a user Friendly MAOI Diet" in the Journal of Clinical Psychiatry, 1996:57(3):99-104 and there is nothing accessable prior to October of that year. How can I get a copy?
> Thanks
> Lisa

Keep in mind that any lists written 1994 or earlier are not necessarily accurate. They updated the lists and added many more items. Things they previously thought were verboten are now accepted. They are still not bad guidelines, but it's better to stick with published lists 1996 and later.

Regarding autolyzed yeast and yeast extract, I've seen it listed on many lists. I sometimes question it's inclusion in the zero allowable column however. I've actually eaten some Ramen soup which contains autolyzed yeast with no reaction. I haven't actually tried it since because I'd rather err on the side of caution, but I wonder if a little would really hurt.

Here's one list, but it's published in 1994: http://www.virtualtrial.com/pcvdiet.cfm

This list from Dr. Bob (referenced to McCabe) mentions yeast extracts: http://www.dr-bob.org/tips/maoi.html#avoid

And here's one more: http://leda.lycaeum.org/Documents/MAOIs_--_Monoamine_Oxidase_Inhibitors.13334.shtml

-Jessica

 

Re: MAOI diet short list » cybercafe

Posted by jsarirose on July 22, 2002, at 3:03:54

In reply to Re: MAOI diet short list, posted by cybercafe on July 22, 2002, at 2:56:24

> > To add to the list - remember any pastes are not allowed at all! For example fish paste & anchovy paste. May sound like something you'd never eat, but they actually use some of those pastes in some of the Asian soups. I was sick from some Vietnamese Pho which I found out contains anchovy paste.
>
> really? my mom keeps trying to push the paste on me...
>
> jess you have saved my butt yet again ...
>
> ... i am going to have to recommend you charge my health care insurance $500

Well, toothpaste is okay! You still have to brush, sorry. ; )

-Jessica

ps - shrimp paste is another

 

Re: MAOI diet short list

Posted by LLL on July 22, 2002, at 10:02:07

In reply to Re: MAOI diet short list » LLL, posted by jsarirose on July 22, 2002, at 3:02:33

> Jess, as always, thank you for your thorough responses. I still have questions because I clearly recall using the frozen diet dinners "Lean Cuisine" etc., the last time I was on Parnate with no incidents and those dinners as well as the other brand names list yeast extract, yeast, or autolyzed yeast extract. I may call the manufacturer because the amount may be so small that restricting the use would be unnecesary.
Raspberries are listed as both not a problem and as a problem in these lists (I have them all). So it makes me question things like bottled raspberry viniagrette dressing. And - if peanuts in large quantity is prohibited - what about peanut butter?
I've written to 2 pharmacists on line and received a response from one who will try to help me further- he's in the UK. This is what he's told me thus far:
The trouble is that there are two problems:
1. Some people are rapid metabolisers of tyramine and in fact hardly need to have a restricted diet
2. Hard data on the exact tyramine content of foods is lacking, and even
then there are variations between brands, it changes over time and one study
even showed local concentrations in one piece of cheese - one chunk had none, another chunk next to it would blow your head off!
I'll post what I find out.
Lisa

 

Re: MAOI diet short list » LLL

Posted by jsarirose on July 22, 2002, at 10:41:32

In reply to Re: MAOI diet short list, posted by LLL on July 22, 2002, at 10:02:07

Please do post if you get a response.

When I see conflicting reports I always look at the date and go with the later one. Usually, it is an item they thought was not allowed and then they realize it's fine.

I've never heard of raspberries causing any trouble and I've eaten fresh raspberries, frozen raspberries, and raspberry jam. Judging from my reaction to other items I would guess I'm a "rapid metabolizer".

And I believe the same is true with peanuts except in very high quantities. I've successfully eaten more peanut butter & jelly sandwiches than I care to admit (and I use pure ground peanuts and don't put it on sparsely).

Some things, like chocolate, do contain tyramine in studies but in practicality you would have to consume so much it really would be difficult to get a reaction. They still tend to include them on the 'use in small quantities' lists though.

There is a list on the web of actual tyramine content in a variety of foods. Here's one (I've seen others but can't find any good ones right now): http://www.migraene.dk/Engelsk/triggers/Tyraminmigr%C3%A6ne-english.htm

General rule of thumb, I believe, is greater than 6mg/serving is a no no, while less than that is allowable in increasing moderation as it nears 6mg.

Another stat for you: A person (not on MAOI) can safely ingest 100mg of tyramine. As the amount increases their blood pressure will increase. 400-500mg causes hypertension. Taking an MAOI causes a 50-fold effect on tyramine levels, hence 6mg of tyramine = 300mg for a "normal" person.
(Paraphrased from a couple sites, including: http://nepenthes.lycaeum.org/Drugs/Misc/maoidisc.html)

-Jessica

 

Re: MAOI diet short list

Posted by jsarirose on July 22, 2002, at 10:53:52

In reply to Re: MAOI diet short list » LLL, posted by jsarirose on July 22, 2002, at 10:41:32

Found one more tidbit: "Approximately 10 to 25 mg of tyramine is required for a severe reaction compared to 6 to 10 mg for a mild reaction." (Source: http://nepenthes.lycaeum.org/Misc/maoi.foods.html)
Granted, this is an older list, but I would think the above rule of thumb is still accurate.

And here's an answer to a question I had a while back but never could get answered. I was wondering if you had several items that were each acceptable in small doses if the total effect could give you a reaction. And, how long does it take to clear your system of tyramine. For example, if I had a bunch of coffee in the morning, could I have a bunch more at night? Anyway: "Tyramine gets digested pretty quickly, and likely clears the gut in 12 hours or so."
(Source: http://www.erowid.org/chemicals/maois/maois_info7.shtml)

Okay - think I'm done browsing for now (maybe). : )

-Jessica

 

Re: MAOI diet short list

Posted by LLL on July 22, 2002, at 11:03:16

In reply to Re: MAOI diet short list, posted by jsarirose on July 22, 2002, at 10:53:52

Thanks again. I think I've already read everything out there and have become addicted to my computer as a result! Do you use peanut butter? What about frozen name brand meals/dinners?
Lisa

 

Re: MAOI diet short list

Posted by jsarirose on July 22, 2002, at 11:15:36

In reply to Re: MAOI diet short list, posted by LLL on July 22, 2002, at 11:03:16

> Thanks again. I think I've already read everything out there and have become addicted to my computer as a result! Do you use peanut butter? What about frozen name brand meals/dinners?
> Lisa

Yes, peanut butter in cooking and sammiches. I've shied away from frozen dinners that contain autolyzed yeast (which is most anything with a sauce). I'm still not convinced that the amount would be enough to trigger an episode, but I'm pretty gun shy these days. When I first started on Parnate I would chance things more and taste more things. Now, after three episodes, I would rather err on the side of caution. I would just love to find some data on the actual mg of tyramine contained in an average serving of something containing autolyzed yeast though. Any friends that are chemists?

-Jessica
(ps - I've found some of the more expensive organic ones don't contain the yeast)


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