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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 24 to 48 of 1085. Go back in thread:
Posted by Lexie on January 22, 2001, at 19:57:02
In reply to Re: Topamax Experiences?, posted by Kingfish on January 22, 2001, at 8:31:49
> Hi! Since I started this thread, I thought I'd add my two cents again, finally. Thanks so much to everyone for the wonderfully helpful information.
>
> As for my experiences in the interim, I have increased my Topamax to 100 mg taken all in the pm because I had a problem with sedation during the day if I took any in the am (I slept three to four hours every day). Like Bob and phillybob, I am having tingling in my hands, especially my fingers, and some soreness. The other effects, such as strange tastes in the mouth, motor problems, have stopped. I'm shooting for 200 mg a day right now. I take 40 mg of Celexa and Neurontin as needed. Am diagnosed as BPII.
>
> Still seems to be helping me, though I do feel I need something more, so hopefully finding an optimum dose will do it.
>
> If anyone finds any new info on the drug, I'm sure we'd all appreciate it. Thus far, it seems like all we know is that Kidney Stones can develop.Hi Kingfish, Phillybob, Bob and Everyone
Glad to hear that the Topamax is working so well. It is the only thing that has worked for me and I have been going down this road a long time and traveling the Topamax/Lamictal Road since June. Like a lot of you I am also BP 2. I have lost weight a total of 30 pounds I am 5' 9" and am a little low for my height so watch what you ask for you just might get it. My doc is threatening to lower the Topamax (remember I take 400 per day, that is the high end) if I don't gain some weight back and I am getting some grief from family about the weight loss. I am having such good luck with the depression lifting especially the suicidal thoughts (that went away when the Lamictal was added, remember I take 500 mgs of Lamictal that is also high, I have been a tough case) I don't want to decrease the Topamax. Looks like I will be having those "Krispy Kremes" for breakfast. The weight loss came about as no longer a craving for sweets that I had with AD's and the craving to binge. As for the odd taste, I had to give up carbonation forever, it makes me gag! The tingling you describe started for me in the beginning but went away, I don't know if it will be the same for everyone, but for me it did go away. Good Luck to all of you. Lexie, AKA the Damn Ms. Lexie Gotta, love you, Phillybob and Thanks to you Kingfish for starting such an interesting thread
>
Posted by Bob on January 22, 2001, at 21:02:23
In reply to Re: Topamax Experiences?, posted by Lexie on January 22, 2001, at 19:57:02
> > Hi! Since I started this thread, I thought I'd add my two cents again, finally. Thanks so much to everyone for the wonderfully helpful information.
> >
> > As for my experiences in the interim, I have increased my Topamax to 100 mg taken all in the pm because I had a problem with sedation during the day if I took any in the am (I slept three to four hours every day). Like Bob and phillybob, I am having tingling in my hands, especially my fingers, and some soreness. The other effects, such as strange tastes in the mouth, motor problems, have stopped. I'm shooting for 200 mg a day right now. I take 40 mg of Celexa and Neurontin as needed. Am diagnosed as BPII.
> >
> > Still seems to be helping me, though I do feel I need something more, so hopefully finding an optimum dose will do it.
> >
> > If anyone finds any new info on the drug, I'm sure we'd all appreciate it. Thus far, it seems like all we know is that Kidney Stones can develop.
>
> Hi Kingfish, Phillybob, Bob and Everyone
> Glad to hear that the Topamax is working so well. It is the only thing that has worked for me and I have been going down this road a long time and traveling the Topamax/Lamictal Road since June. Like a lot of you I am also BP 2. I have lost weight a total of 30 pounds I am 5' 9" and am a little low for my height so watch what you ask for you just might get it. My doc is threatening to lower the Topamax (remember I take 400 per day, that is the high end) if I don't gain some weight back and I am getting some grief from family about the weight loss. I am having such good luck with the depression lifting especially the suicidal thoughts (that went away when the Lamictal was added, remember I take 500 mgs of Lamictal that is also high, I have been a tough case) I don't want to decrease the Topamax. Looks like I will be having those "Krispy Kremes" for breakfast. The weight loss came about as no longer a craving for sweets that I had with AD's and the craving to binge. As for the odd taste, I had to give up carbonation forever, it makes me gag! The tingling you describe started for me in the beginning but went away, I don't know if it will be the same for everyone, but for me it did go away. Good Luck to all of you. Lexie, AKA the Damn Ms. Lexie Gotta, love you, Phillybob and Thanks to you Kingfish for starting such an interesting thread
> >Lexie:
Just a couple of quick questions... I am a relative newcomer to this thread.
How long did it take you to build up to, and then stabilize on those high doses of lamictal and topomax; in other words, to get where you are now?
Is that all you are taking is those two meds, or are you supplementing with others? Are you getting good AD effects from them?
Bob
Posted by natg on January 23, 2001, at 3:54:24
In reply to Re: Topamax Experiences?, posted by Bob on January 22, 2001, at 21:02:23
Hi,
i have a question for my sister who has a binge- eating disorder. Would Topomax be an option for her? If so, how exactly is it helpful?Feedback and suggestions appreciated.
Nat
Posted by Lexie on January 23, 2001, at 5:00:53
In reply to Re: Topamax Experiences?, posted by Bob on January 22, 2001, at 21:02:23
> > >
>
> Lexie:
>
> Just a couple of quick questions... I am a relative newcomer to this thread.
>
> How long did it take you to build up to, and then stabilize on those high doses of lamictal and topomax; in other words, to get where you are now?
>
> Is that all you are taking is those two meds, or are you supplementing with others? Are you getting good AD effects from them?
>
> BobI took just Topamax from June to September and got relief at about the 250 level and the optimum relief at 400. Topamax helped me mostly with the anger and acting out highs. I was experiencing a lot of suicidal thoughts and severe depression when my doctor added the Lamictal. It was added in a starter pack slowly because you can get a sometimes very serious rash if started to quickly. The manufacture makes a started pack that your doctor will give you at no charge (mine did). That takes 5 weeks at the end of 5 weeks you are up to 150 it still goes slowly from there it was the beginning of November and tons of support from Noa that kept going without giving up to make it to the 500 level, my doctor says that for my condition Topamax max's out at 400 and Lamictal max's out at 600, I plan to stay where I am with the Lamictal. I take no other AD's the Lamictal is more than I could have ever hoped for. I am sure the results are not for everyone, but it worked for me. My doctor has been known as one of the best in my area for Medication issue's. I am VERY lucky. I am also very lucky to insurance, without it these meds would cost 600.00 per month. Good Luck, Lexie
Posted by Lexie on January 23, 2001, at 5:08:42
In reply to Topomax question, posted by natg on January 23, 2001, at 3:54:24
> Hi,
> i have a question for my sister who has a binge- eating disorder. Would Topomax be an option for her? If so, how exactly is it helpful?
>
> Feedback and suggestions appreciated.
>
> NatI read a while back, when first researching this medication that a University did a research project on Binge eating and Topamax. It was a Controlled study where some participants were given Topamax and some a placebo. The ones given the Topamax did far better controlling their binge eating than the ones taking the placebo. I was taking it for BP 2, I stopped binging and lost 30 pounds) I just don't know if a Doctor will prescribe to for that, although they perscribe it for BP and it is only FDA approved for eplipsy, so who know's? Hope this helps. But I am no doctor just someone offering some advise. All My Best, Lexie
Posted by KarenK on January 23, 2001, at 11:39:06
In reply to Re: Topamax Experiences?, posted by Kingfish on January 22, 2001, at 8:31:49
There was an article on topamax in Medscape on cognitive dysfunction. I'll include the link. I'm finding that this side effect is largely going away with time. What do you think? Comments?
http://jnnp.bmjjournals.com/cgi/content/abstract/69/5/636
KarenK
Posted by phillybob on January 23, 2001, at 18:56:41
In reply to Re: Topamax Experiences?, posted by KarenK on January 23, 2001, at 11:39:06
Karen, regarding cognitive dysfunction, I'll agree that it seems to dissipate, more or less, the more that the time has elapsed from the last dosage increase. I am sure, however, those tremendously sensitive to intellectual "calibrations" would notice something, but for me, no me importa (Spanish for this is of no importance to me).
natg, I am certain that medscape had had an article pointing to the efficacy of topiramate in the treatment of binge eating. My own anecdotal consumption experiences (at about a 225 mg/day dosage), however, are quite humorous. Whereas I did not finish my cheese fries at lunch today (something I would have never heretofore have done), I did just now eat an entire sleeve of Snackwell crackers (something I always have been inclined to do and do quite well, I might add). Sigh. :)
Posted by Bob on January 23, 2001, at 21:30:33
In reply to Topomax question, posted by natg on January 23, 2001, at 3:54:24
> Hi,
> i have a question for my sister who has a binge- eating disorder. Would Topomax be an option for her? If so, how exactly is it helpful?
>
> Feedback and suggestions appreciated.
>
> NatMy personal opinion here would be, if she needs emergency relief, she should go on an established SSRI first, and then maybe transition to somthing like topomax later. I don't think mood stabilizers and anti-siezure meds have been shown to have strong anti-obsessive properties... but I could be completely wrong here. I would not advise anybode to take my word alone for it. Ask a medical professional!
Posted by Bob on January 23, 2001, at 21:32:35
In reply to Re: Topamax Experiences?, posted by Lexie on January 23, 2001, at 5:00:53
> > > >
> >
> > Lexie:
> >
> > Just a couple of quick questions... I am a relative newcomer to this thread.
> >
> > How long did it take you to build up to, and then stabilize on those high doses of lamictal and topomax; in other words, to get where you are now?
> >
> > Is that all you are taking is those two meds, or are you supplementing with others? Are you getting good AD effects from them?
> >
> > Bob
>
> I took just Topamax from June to September and got relief at about the 250 level and the optimum relief at 400. Topamax helped me mostly with the anger and acting out highs. I was experiencing a lot of suicidal thoughts and severe depression when my doctor added the Lamictal. It was added in a starter pack slowly because you can get a sometimes very serious rash if started to quickly. The manufacture makes a started pack that your doctor will give you at no charge (mine did). That takes 5 weeks at the end of 5 weeks you are up to 150 it still goes slowly from there it was the beginning of November and tons of support from Noa that kept going without giving up to make it to the 500 level, my doctor says that for my condition Topamax max's out at 400 and Lamictal max's out at 600, I plan to stay where I am with the Lamictal. I take no other AD's the Lamictal is more than I could have ever hoped for. I am sure the results are not for everyone, but it worked for me. My doctor has been known as one of the best in my area for Medication issue's. I am VERY lucky. I am also very lucky to insurance, without it these meds would cost 600.00 per month. Good Luck, LexieLexie:
I'm glad to hear it is working out for you! By the way... where is your area, anyway?
Posted by Bob on January 23, 2001, at 21:38:31
In reply to Re: Topomax question, posted by Bob on January 23, 2001, at 21:30:33
> > Hi,
> > i have a question for my sister who has a binge- eating disorder. Would Topomax be an option for her? If so, how exactly is it helpful?
> >
> > Feedback and suggestions appreciated.
> >
> > Nat
>
> My personal opinion here would be, if she needs emergency relief, she should go on an established SSRI first, and then maybe transition to somthing like topomax later. I don't think mood stabilizers and anti-siezure meds have been shown to have strong anti-obsessive properties... but I could be completely wrong here. I would not advise anybode to take my word alone for it. Ask a medical professional!On second thought, scratch what I just said! I was thinking about anorexia, not binge eating. You are actually looking for the appetite suppressing properties of topomax. I wasn't thinking there. Nevermind. Disregard what I said, and sorry about that.
Posted by Lexie on January 24, 2001, at 4:41:22
In reply to Re: Topamax Experiences?, posted by Bob on January 23, 2001, at 21:32:35
> > > > >
> > >
> > > Lexie:
> > >
>
> I'm glad to hear it is working out for you! By the way... where is your area, anyway?I live in Orlando, Florida. If you live in the area I will give you the name of my Pdoc. He is really the best. Lexie
Posted by maribeth on January 24, 2001, at 6:34:33
In reply to Re: Topamax Experiences?, posted by Lexie on January 24, 2001, at 4:41:22
> > > > > >
> > > >
> > > > Lexie:
> > > >
> >
> > I'm glad to hear it is working out for you! By the way... where is your area, anyway?
>
> I live in Orlando, Florida. If you live in the area I will give you the name of my Pdoc. He is really the best. LexieTo all you fellow Topomax folks,
I'm really glad to have gotten involved with this thread. Saw my pdoc yesterday. He seems interested in this group also
He originally started me on the Topomax to see if it would promote some weight loss.
As I have said in prior postings I am not supposed to be bi-polar, my moods have certainly changed! They Seem to have "smoothed out". No more quick witted
sarcastic retorts". No, more "too sensitive" hurt feelings or crying at the drop of a hat. I am now able to sit in a group without having
to make a comment. And, as for the cognitive stuff -- this may be a bit of a silly measure of that, but my husband and I are "Jeopardy Freaks"
and at first (when I was on 50 to 200 mgs per day I was a bit slow and cloudy and I almost gave the Topomax up. However, Im now on300mgm
and working up to 500mgm and all side effects (including the congnitive stuff) seem to have dissappeared. However, I am fifty-seven years
old,so who knows!! Thanks for your support and do hang in there all of you. Blessings--Maribeth
Posted by Vince on January 24, 2001, at 10:28:58
In reply to Re: Topamax Experiences?, posted by maribeth on January 24, 2001, at 6:34:33
> > > > > > >
> > > > >
> > > > > Lexie:
> > > > >
> > >
> > > I'm glad to hear it is working out for you! By the way... where is your area, anyway?
> >
> > I live in Orlando, Florida. If you live in the area I will give you the name of my Pdoc. He is really the best. Lexie
>
> To all you fellow Topomax folks,
> I'm really glad to have gotten involved with this thread. Saw my pdoc yesterday. He seems interested in this group also
> He originally started me on the Topomax to see if it would promote some weight loss.
> As I have said in prior postings I am not supposed to be bi-polar, my moods have certainly changed! They Seem to have "smoothed out". No more quick witted
> sarcastic retorts". No, more "too sensitive" hurt feelings or crying at the drop of a hat. I am now able to sit in a group without having
> to make a comment. And, as for the cognitive stuff -- this may be a bit of a silly measure of that, but my husband and I are "Jeopardy Freaks"
> and at first (when I was on 50 to 200 mgs per day I was a bit slow and cloudy and I almost gave the Topomax up. However, Im now on300mgm
> and working up to 500mgm and all side effects (including the congnitive stuff) seem to have dissappeared. However, I am fifty-seven years
> old,so who knows!! Thanks for your support and do hang in there all of you. Blessings--Maribeth
Maribeth,Glad to hear it has helped with your moods. Have you had any weight loss? How long have you been on it?
When you said, "No more quick witted sarcastic remarks, No, more too sensitive hurt feelings", I immediatly thought of my sister. She is on Paxil now for depression. I think that she could use Topomax but I don't know how to suggest it too her without getting hit with a sarcastic quick witted retort or hurting her feelings.
I've been feeling around for a mood stablizer. I've been on nuerontin because of an article that I read on Ivan Goldberg's web site, but I had my psychiatrist switch me to Topamax yesterday because the nuerontin didn't seem to be doing anything and because I was hoping Topamax would help me lose some weight.
Vince
Posted by sherry gomez on January 24, 2001, at 18:21:32
In reply to Re: Topamax Experiences? » maribeth, posted by Vince on January 24, 2001, at 10:28:58
Hi I am new to this... I take topamax for bipolar. Does anyone get sores on their tongues from it. I take 300mg. Along with prozac. I do like it because with depakote I had problems with weight gain.
Posted by maribeth on January 25, 2001, at 7:37:38
In reply to Re: Topamax Experiences? Â, posted by sherry gomez on January 24, 2001, at 18:21:32
> Hi I am new to this... I take topamax for bipolar. Does anyone get sores on their tongues from it. I take 300mg. Along with prozac. I do like it because with depakote I had problems with weight gain.
Sherry,
Yes, I had terrible mouth sorer for about the first week that I was
on Topamax. I used one of the over the counter agents to numb my mouth
then had my doc order some Xylocaine2%. The sores went away and haven't
come back, Maribeth
Posted by Kingfish on January 25, 2001, at 16:30:37
In reply to Re: Topamax Experiences? Â » sherry gomez, posted by maribeth on January 25, 2001, at 7:37:38
I still can't believe all the wonderful info being gathered here about this med. Thanks!
I have a ? re: sedation - I can't seem to get above 100mg a day, even if I take it all at night. It is helping, as I've mentioned, even at that low dose, but my psych. and I would like to get it higher. I've tried three times now at 125 mg. for up to a week at a time and I sleep at least 3-4 hours a day and feel horrible.
Has anyone else had this problem? Is there something to take to counteract it (though I really don't want to get into more meds if possible). :(
Thanks!
Posted by KarenK on January 25, 2001, at 18:02:35
In reply to Re: Topamax Experiences?, posted by Bob on January 23, 2001, at 21:32:35
< Topamax helped me mostly with the anger and acting out highs >
Folks,
I put the topamax to the test today. I drove in NYC midtown traffic. Now when I was on the depakote, I really didn't feel the need to honk my horn and definitely did not yell at cab drivers no matter how stupid their driving was. I just stopped the depakote this week and I'm on 125mg of topamax. I see my pdoc tomorrow. Is the anger control dose dependent?
KarenK
Posted by KarenK on January 25, 2001, at 18:11:27
In reply to Re: Topamax Experiences?, posted by maribeth on January 24, 2001, at 6:34:33
Maribeth,
I started on Topamax for the same reason as you, to lose weight. I'm not supposed to be bipolar, but I am moody and your comments about sarcastic remarks fits me to a tee. I was on prozac, depakote, and topamax. Now that the depakote is out, my sarcasm is back. I don't have to make a comment like I used to, but then I don't have to. I have one of those very expressive faces. I have to talk to my pdoc about this. Maybe an increase in dose will help. I'm glad it's working for you. It gives me hope.
Love,
KarenK>
> To all you fellow Topomax folks,
> I'm really glad to have gotten involved with this thread. Saw my pdoc yesterday. He seems interested in this group also
> He originally started me on the Topomax to see if it would promote some weight loss.
> As I have said in prior postings I am not supposed to be bi-polar, my moods have certainly changed! They Seem to have "smoothed out". No more quick witted
> sarcastic retorts". No, more "too sensitive" hurt feelings or crying at the drop of a hat. I am now able to sit in a group without having
> to make a comment. And, as for the cognitive stuff -- this may be a bit of a silly measure of that, but my husband and I are "Jeopardy Freaks"
> and at first (when I was on 50 to 200 mgs per day I was a bit slow and cloudy and I almost gave the Topomax up. However, Im now on300mgm
> and working up to 500mgm and all side effects (including the congnitive stuff) seem to have dissappeared. However, I am fifty-seven years
> old,so who knows!! Thanks for your support and do hang in there all of you. Blessings--Maribeth
Posted by KarenK on January 25, 2001, at 18:13:39
In reply to Re: Topamax Experiences? Â, posted by sherry gomez on January 24, 2001, at 18:21:32
Sherry,
No, but my gums sure are sore. I'm on prozac too and I got off depakote for the same reason as you.
KarenK
> Hi I am new to this... I take topamax for bipolar. Does anyone get sores on their tongues from it. I take 300mg. Along with prozac. I do like it because with depakote I had problems with weight gain.
Posted by KarenK on January 25, 2001, at 18:39:48
In reply to Re: Topamax Experiences? Â, posted by KarenK on January 25, 2001, at 18:13:39
> Sherry,
>
I was reading your other post about topamax not having the same calming effect as lithium and depakote. I totally agree. Does anyone find topamax to have a calming effect on them?KarenK
Posted by Lexie on January 25, 2001, at 19:43:28
In reply to Re: Topamax Experiences?, posted by KarenK on January 25, 2001, at 18:02:35
> < Topamax helped me mostly with the anger and acting out highs >
>
> Folks,
>
> I put the topamax to the test today. I drove in NYC midtown traffic. Now when I was on the depakote, I really didn't feel the need to honk my horn and definitely did not yell at cab drivers no matter how stupid their driving was. I just stopped the depakote this week and I'm on 125mg of topamax. I see my pdoc tomorrow. Is the anger control dose dependent?
>
> KarenKKarenK
I was the one that made the above comment and for me it was dose dependent the anger control and acting out was not under control until I was at about the 200 level. Keep in mind it is not a magic bullet it took at least 2 weeks to build the tolerance to control these tendences. I hope this works as well for you as the depakote. I am sure it doesn't work for everyone. The advantage of Topamax is not having to go for the blood testing. Good luck and remember it is important to do what works for you. Lexie
Posted by phillybob on January 25, 2001, at 23:21:16
In reply to Re: Topamax Experiences? » KarenK, posted by Lexie on January 25, 2001, at 19:43:28
Anger/Highs: I'd say I feel a bit more "engaging" with topiramate than without it (though I can not compare it to it having been on either Depakote or Lithium because I had not been on either one of those for any significant period of time). I do seem to get angry and do seem to get high but not in an unhealthy way. I most certainly do not seem numb or desensitized to such sensations. They are in no way out of control.
Sedation (to Kingfish, in particular): I knew exactly what you were talking about. If you you re-read my earlier posts, you shall see. I was fortunate to have the liesure to increase the dosage at a fairly quick pace with not much daily obligation pressures so sleeping/napping was not a huge problem for me. However, once the dosage surpassed the 150 mg (I think)/day mark, the daytime sedation seem to begin to dissipate. Perhaps, if you can find some way to find the freedom of time to experiment in increasing the dosage and sustaining/maintaining it at such higher levels, you might find the same ... ?
Sores: I do now recall mouth sores, now that you mention it, but no longer evident.
P.S. Still tootin' along just fine. Went bowling tonight with pals (of course, none of us are bowlers :)
Posted by Kingfish on January 30, 2001, at 5:30:31
In reply to Re: Topamax - Anger/Highs, Sedation, Sores, posted by phillybob on January 25, 2001, at 23:21:16
phillybob:
thank you for the suggestion re: dosage and sedation. I am at a larger dose now (150) and the sedation does seem to be better. I appreciate the advice!
Posted by maribeth on January 30, 2001, at 7:56:05
In reply to Re: Topamax - Anger/Highs, Sedation, Sores » phillybob, posted by Kingfish on January 30, 2001, at 5:30:31
> phillybob:
>
> thank you for the suggestion re: dosage and sedation. I am at a larger dose now (150) and the sedation does seem to be better. I appreciate the advice!Hi y'all
I pretty much agree with all of you. I seem to have the most calming "smoothed out" effect around 200mgm However,
my pdoc wants to take me up to 300 or 400mgm as at 200 the effect is not well sustained and the weightloss/appetite
supression is not working. Right now I have the luxury of being able to be at home or where i can "titrate" the dose.
(monitor dose/effect) and my pdoc is very good about this. Hang in there you all. Sorry I can't relate to the Depakote
etc, but this is the first "mood stabalizer" I have ever been on. (I did the mouth sore bit though; Xylocaine 2% from
the family doc worked well-also stay away from toothpastes with sodium (something)laureate.
Blessings Maribeth
Posted by sherry gomez on January 30, 2001, at 14:59:42
In reply to Re: Topamax - Anger/Highs, Sedation, Sores, posted by maribeth on January 30, 2001, at 7:56:05
> > phillybob:
> >
> > thank you for the suggestion re: dosage and sedation. I am at a larger dose now (150) and the sedation does seem to be better. I appreciate the advice!
>
> Hi y'all
> I pretty much agree with all of you. I seem to have the most calming "smoothed out" effect around 200mgm However,
> my pdoc wants to take me up to 300 or 400mgm as at 200 the effect is not well sustained and the weightloss/appetite
> supression is not working. Right now I have the luxury of being able to be at home or where i can "titrate" the dose.
> (monitor dose/effect) and my pdoc is very good about this. Hang in there you all. Sorry I can't relate to the Depakote
> etc, but this is the first "mood stabalizer" I have ever been on. (I did the mouth sore bit though; Xylocaine 2% from
> the family doc worked well-also stay away from toothpastes with sodium (something)laureate.
> Blessings Maribeth
hi, I am
seeing the doctor this friday, am on 300mg of topamax, I really want to say on it, but I dont think my husband wants me to stay on it as by moods are still roller coastering, if fact he is taking the day off on friday to take to to the doctor. I wish I could get rid of these sores on my tongue..I am so afraid they are going to put me back on depakote. Anyway I lost nearly 40 pounds!! I am down to 103pnds.
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