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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 60 to 84 of 164. Go back in thread:
Posted by Michael on May 13, 1999, at 13:09:37
In reply to Re: naltrexone mailing list, posted by Wayne R. on May 11, 1999, at 5:32:09
> Hey Mike!
>
> May you become the permanent “King of the world”!! I guess my only words of wisdom are to start slowly. Work the dosage up very gradually to allow your system to adjust. God, I would just love to have others duplicate the success I have had. Keep me posted and send me specific questions if they come up.
>
> WayneHey Wayne,
I thought I was starting low at only a quarter of a 50mg pill. The first day was okay, but the second day I felt nauseous, dizzy and tired. I also had a pretty bad headache. I skipped taking it today and I still feel lousy. I know it stays in your sytem for like 72 hours just like Prozac. I'm just wondering if what I'm experiencing sounds normal to you and should I just take a quarter pill every third day or some other protocol. I've tried so many things, with so many bad reactions I'm really getting pretty fed up. Please advise me as to what you think I should do. I hope to read back from you soon.
Mike
Posted by Wayne R. on May 13, 1999, at 14:56:35
In reply to Not doing so good., posted by Michael on May 13, 1999, at 13:09:37
> Hey Wayne,
>
I'm just wondering if what I'm experiencing sounds normal to you and should I just take a quarter pill every third day or some other protocol.
> Mike
Mike, Like most meds I am not sure there is a "normal" since we are all so different. As for me I broke a 50 mg tablet into 7 pieces and took the smallest piece first, etc. That worked well for me but if you are especially sensitive you might go with tiny fragments for several days until things even out and then go to a slightly larger fragment. Wishing you the best... Wayne
Posted by saintjames on May 13, 1999, at 15:05:01
In reply to Not doing so good., posted by Michael on May 13, 1999, at 13:09:37
> > Hey Mike!
> >
> > May you become the permanent “King of the world”!! I guess my only words of wisdom are to start slowly. Work the dosage up very gradually to allow your system to adjust. God, I would just love to have others duplicate the success I have had. Keep me posted and send me specific questions if they come up.
> > Wayne
>
> Hey Wayne,
>
> I thought I was starting low at only a quarter of a 50mg pill. The first day was okay, but the second day I felt nauseous, dizzy and tired. I also had a pretty bad headache. I skipped taking it today and I still feel lousy. I know it stays in your sytem for like 72 hours just like Prozac. I'm just wondering if what I'm experiencing sounds normal to you and should I just take a quarter pill every third day or some other protocol. I've tried so many things, with so many bad reactions I'm really getting pretty fed up. Please advise me as to what you think I should do. I hope to read back from you soon.
>
> MikeJames here....
Prozac lasts far longer than 72 hrs. Side effects are always going to be bad the first week. For me, unless they are life threatning I have always sit them out to see if they lessen and the med works.
james
Posted by Jim on May 14, 1999, at 6:15:07
In reply to Not doing so good., posted by Michael on May 13, 1999, at 13:09:37
Jim here, former would-be naltrexone poster-boy (see last months posts). I agree with Wayne that the key may to start with VERY small doses--I overshot even by taking an eighth of a pill for the first few days: nightmares, insomnia, etc. After curiously feeling terrific a few days after stopping the naltrexone, I restarted and did much better on very small fractional doses (i.e. 1 or 2 mg a day, or even every other day--the kind of doses you would expect only to have an effect on opiate abusers, but had a profound effect on me). I reluctantly discontinued it recently because it was giving me the same sort of idiosyncratic side-effects I get with SSRIs, but low dosages seemed to work well for a while, especially for cutting back the food cravings that have now all returned with a vengence! In sum, I think the 25 or 50mg dosage may be too high for many people, at least to start with.
Good luck,
Jim
> Hey Wayne,
>
> I thought I was starting low at only a quarter of a 50mg pill. The first day was okay, but the second day I felt nauseous, dizzy and tired. I also had a pretty bad headache. I skipped taking it today and I still feel lousy. I know it stays in your sytem for like 72 hours just like Prozac. I'm just wondering if what I'm experiencing sounds normal to you and should I just take a quarter pill every third day or some other protocol. I've tried so many things, with so many bad reactions I'm really getting pretty fed up. Please advise me as to what you think I should do. I hope to read back from you soon.
>
> Mike
Posted by PattyG on May 14, 1999, at 19:26:33
In reply to Re: Not doing so good., posted by Jim on May 14, 1999, at 6:15:07
Glad to hear (well, not really "glad") that others are having same experience as my husband. Poor soul was really nauseated and dizzy the first day on 25 mg. Thankfully, he cut it in half! We're trying the "break it into quite a few pieces" process and starting over. Anyone with experience know if eventually your system becomes accilamated?
Posted by Michael on May 17, 1999, at 14:30:49
In reply to Re: Not doing so good., posted by PattyG on May 14, 1999, at 19:26:33
> Glad to hear (well, not really "glad") that others are having same experience as my husband. Poor soul was really nauseated and dizzy the first day on 25 mg. Thankfully, he cut it in half! We're trying the "break it into quite a few pieces" process and starting over. Anyone with experience know if eventually your system becomes accilamated?
Please keep me posted!! I've given up for the time being. I just felt so horrible for about 3 days after taking the second dose that I'm afraid to try again. I'm not doing all that great in general but at least I don't feel as bad as I did. I've experimented so much lately that I just need some time to relax. I need a little stability before I try anything again.
Posted by PattyG on May 18, 1999, at 11:27:27
In reply to Re: Not doing so good., posted by Michael on May 17, 1999, at 14:30:49
Sorry you're having the same problems. I've broken the tablet into fractions of fractions and he still complains of headaches, some nausea, and loose bowels. Even took a dose with two aspirin and started taking it at bedtime, but to no avail. Also, anyone know if Naltrexone is the generic for Revia (the way our insurance worked, it would appear to be.) If so, wondered if that could be part of the problem? Anyone know? And.........how about Kudzuroot? It's supposed to be the "natural" Naltrexone - anyone try that yet?
Posted by chuck on May 18, 1999, at 12:15:50
In reply to opioid agonist/antagonist discussion mailing list, posted by Elizabeth on April 20, 1999, at 17:28:53
>I would love to get on this mailing list---->started taking naltrexone about 4 weeks ago (with Zoloft, for last four years) with some results, though I'm not altogether sure what they are; that is, if if has 'boosted' my SSRI, it has done so only slightly. thanks.
Posted by chuck on May 18, 1999, at 12:16:00
In reply to opioid agonist/antagonist discussion mailing list, posted by Elizabeth on April 20, 1999, at 17:28:53
>I would love to get on this mailing list---->started taking naltrexone about 4 weeks ago (with Zoloft, for last four years) with some results, though I'm not altogether sure what they are; that is, if if has 'boosted' my SSRI, it has done so only slightly. thanks.
Posted by Elizabeth on May 18, 1999, at 17:52:35
In reply to Re: Not doing so good., posted by PattyG on May 18, 1999, at 11:27:27
Yeah, Revia is a brand name of naltrexone. (Another one I've heard is Trexan.)
The active ingredients in kudzu root are alcohol dehydrogenase inhibitors, I think...it doesn't work the same way as naltrexone does, anyway.
Posted by PattyG on May 18, 1999, at 23:35:41
In reply to naltrexone - Patty, posted by Elizabeth on May 18, 1999, at 17:52:35
(Elizabeth wrote)Yeah, Revia is a brand name of naltrexone. (Another one I've heard is Trexan.)
The active ingredients in kudzu root are alcohol dehydrogenase inhibitors, I think...it doesn't work the same way
as naltrexone does, anyway.////Sorry for being so....dumb....but are you saying that Naltrexone is, then, the generic of Revia? And what is Trexan? Haven't heard of that one. Also, I attended a workshop at the State Mental Health Convention on the Neurobiology of Addiction and the psychiatrist mentioned Kudzuroot and I was under the impression that he was inferring this worked in the same manner as Naltrexone. In what way do you know it to be effective? Thanks for any info you have!
Posted by Wayne R. on May 19, 1999, at 5:42:34
In reply to Re: naltrexone - Patty, posted by PattyG on May 18, 1999, at 23:35:41
Patty,
Naltrexone is the generic name. It has only been available as a generic for a year or so. Revia and Trexan are manufacturers brand names of the same thing.
Naltrexone has FDA approval for the treatment of certain drug and alcohol addictions. It fills in or blocks the receptors that influence the action of and craving for those drugs, etc. Naltrexone was accidentally discovered to help some people with hard to treat depression when combined with an SSRI type antidepressant. Nobody seems to know why this even works as yet. You may wish to review my postings since February to get more information. Best regards… Wayne
Posted by PattyG on May 19, 1999, at 7:33:20
In reply to Re: naltrexone - Patty, posted by Wayne R. on May 19, 1999, at 5:42:34
Okay, now what I need to know is if it could be possible that the folks who are having difficulty taking Naltrexone (headaches, nausea, etc.) would fair better with Revia (the non-generic drug?) Anyone have any info on this? THanks much!
Posted by Wayne R. on May 19, 1999, at 11:56:50
In reply to Re: naltrexone - Wayne, posted by PattyG on May 19, 1999, at 7:33:20
The generics are supposed to be made to the same standards and so it should not make any difference. I started on Revia and switched to the generic Naltrexone and I have noticed no difference in relief, side effects (none for me), etc. Wayne
Posted by Elizabeth on May 20, 1999, at 2:19:10
In reply to Re: naltrexone - Patty, posted by Wayne R. on May 19, 1999, at 11:56:50
Hi Patty. You're not dumb - I'm sorry if it sounded like I was talking down to you!
As to the mechanism of kudzu root, I looked into it some more and it doesn't seem like it's quite that simple. But I *don't* know of any evidence that it works in the way that naltrexone is known to work.
There are a couple of studies that have been done or are being done in rodents. I remember some stuff a few years ago by Keung and colleagues. I don't know if they're still working on it.
Posted by Dr Haraldur Erlendsson on February 1, 2000, at 8:02:22
In reply to Re: Refractory depression--naltrexone theories?, posted by Jim on April 14, 1999, at 7:37:18
Are you aware of the animal studies
of learned helplessness and
naltrexone
Posted by PattyG on February 1, 2000, at 21:04:19
In reply to Re: Refractory depression--naltrexone theories?, posted by Dr Haraldur Erlendsson on February 1, 2000, at 8:02:22
> Are you aware of the animal studies
> of learned helplessness and
> naltrexone////No. Please advise!
Posted by Anna P. on February 3, 2000, at 16:54:50
In reply to Re: Refractory depression--naltrexone theories?, posted by PattyG on February 1, 2000, at 21:04:19
> > Are you aware of the animal studies
> > of learned helplessness and
> > naltrexone
>
> ////No. Please advise!Naltrexone has helped me to avoid Lithium( I'm already seriously overweight) by preventing the fading of the antidepressant.
Anna P.
Posted by Scott L. Schofield on February 6, 2000, at 9:28:58
In reply to Re: Refractory depression--naltrexone theories?, posted by Anna P. on February 3, 2000, at 16:54:50
> Naltrexone has helped me to avoid Lithium( I'm already seriously overweight) by preventing the fading of the antidepressant.
Which one?
Thanks.
- Scott
Posted by Janet from Brazil on February 6, 2000, at 15:56:43
In reply to Re: Refractory depression--naltrexone theories?, posted by Dr Haraldur Erlendsson on February 1, 2000, at 8:02:22
> Are you aware of the animal studies
> of learned helplessness and
> naltrexoneCould you please give me a synopsis of these studies as I'M interested.Thank you
Posted by Anna P. on February 8, 2000, at 21:48:37
In reply to Re: Refractory depression--naltrexone theories?, posted by Scott L. Schofield on February 6, 2000, at 9:28:58
> > Naltrexone has helped me to avoid Lithium( I'm already seriously overweight) by preventing the fading of the antidepressant.
>
> Which one?
>
> I've found out the only combo working for me is Moclobemide - Naltrexone, but I read that Naltrexone helps with SSIR's poop out.
Whereas all medication stop working in my case, a single doze of the Naltrexone stays in my body for up to 8 hours,
augmenting Moclobemide.Anna P.
Posted by Fred Potter on January 23, 2001, at 16:24:50
In reply to opioid agonist/antagonist discussion mailing list, posted by Elizabeth on April 20, 1999, at 17:28:53
25 mg of Naltrexone augmenting 40mg Prozac has given me the fullest antidepressant anti-anxiety response I've had in all my 37 years of suffering. It's very expensive though, and some family friction is being caused by this. If it's not too late to be put on the mailing list I would be most grateful. I'm a fan
Fred
Posted by J.Lester on January 25, 2001, at 19:45:57
In reply to Re: opioid agonist/antagonist discussion mailing list, posted by Fred Potter on January 23, 2001, at 16:24:50
> 25 mg of Naltrexone augmenting 40mg Prozac has given me the fullest antidepressant anti-anxiety response I've had in all my 37 years of suffering. It's very expensive though, and some family friction is being caused by this. If it's not too late to be put on the mailing list I would be most grateful. I'm a fan
> FredIs it true that it's only effective with SSRIs ? I hate them. How about the rest of ADs ?
Posted by SLS on January 25, 2001, at 21:34:31
In reply to Naltrexone only with SSRIs ?, posted by J.Lester on January 25, 2001, at 19:45:57
> > 25 mg of Naltrexone augmenting 40mg Prozac has given me the fullest antidepressant anti-anxiety response I've had in all my 37 years of suffering. It's very expensive though, and some family friction is being caused by this. If it's not too late to be put on the mailing list I would be most grateful. I'm a fan
> > Fred
>
> Is it true that it's only effective with SSRIs ? I hate them. How about the rest of ADs ?
It seems to work with Nardil.
- Scott
Posted by ChrisK on January 26, 2001, at 5:26:47
In reply to Naltrexone only with SSRIs ?, posted by J.Lester on January 25, 2001, at 19:45:57
I've taken it succesfully with Nortriptyline.
> > 25 mg of Naltrexone augmenting 40mg Prozac has given me the fullest antidepressant anti-anxiety response I've had in all my 37 years of suffering. It's very expensive though, and some family friction is being caused by this. If it's not too late to be put on the mailing list I would be most grateful. I'm a fan
> > Fred
>
> Is it true that it's only effective with SSRIs ? I hate them. How about the rest of ADs ?
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Dr. Bob is Robert Hsiung, MD,
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