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Dr. Bob is Robert Hsiung, MD,
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Posted by nancy on April 21, 1999, at 12:00:06
In reply to Re: topomax, posted by katie on April 20, 1999, at 22:38:44
Actually, pills do change feeling, thoughts, desires...and some of them do disrupt one's physiology significantly causing weight gain or loss.
When I took Topomax, I was replused by just the thought of food. Also, I could only tolerate water to quench my thirst...well, ok, I could drink coffee. But any other type of liquid had a disgusting flavor.
I have been taking Seroquel instead of Topomax, recently, to satisfy my pdoc curiosity about my potential response to these completely different mood stabilizers.
I'm going to get back on the Topomax and DROP the Seroquel. Topomax is an AED, whereas, Seroquel is an atypical antipsychotic...I'm getting dyskinesia in my hands. In my experience, Topomax is the mood stabilizer of CHOICE (granted, if one has a choice) for any severe manic depressive w/, rapid cycling, mixed states, and/or intolerance to other AEDs.
> >My Dr. has prescribed topomax for me to eventually replace the lithium. I've taken it about a week and will up the dose to what will be my normal level tomorrow. So far I haven't really noticed my appetite changing at all. But I'm still taking the lithium too. I know that losing weight really comes down to what the individual wants and is willing to do to attain a goal. I feel you can't put too much stock into a pill to solve all your problems. Don't get me wrong...I need those durn things to help me through my day, but ultimately I control my destiny. (It is kinda nice to think that some prescription drugs have desirable "side-effects".)
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> Topomax is suppose to do the opposite from depakote in terms of instead of weight gain it has weight loss side effects. Has anyone had any experience with these? Ellen
Posted by katie on April 21, 1999, at 14:19:09
In reply to Re: topomax, posted by nancy on April 21, 1999, at 12:00:06
Also, I could only tolerate water to quench my thirst...well, ok, I could drink coffee. But any other type of liquid had a disgusting flavor.
>In response to above statement I have noticed a heightened sense of taste with everything from morning breath to how refreshing a really cold soda tastes. But most of the time I notice a kind of metallic taste.
Posted by Toby on April 26, 1999, at 10:49:35
In reply to Re: topomax, posted by katie on April 21, 1999, at 14:19:09
What kinds of doses are working for you ladies? I've seen everything from 100 mg per day to 600 mg per day in the studies, but the studies also indicate that the higher doses make people cognitively dull. I have only one patient on it now (at 100 mg) and she's still got a little bit in the way of hypomania so we're slowly going to go up to 150 mg. She's very bright and in graduate school so I'm being cautious because I don't want to dull her intellect or creativeness, but at the same time when she's manic she doesn't get a whole lot of useful activities done either. I'm hoping we can find a happy medium with the Topamax.
Posted by katie on April 26, 1999, at 13:16:19
In reply to Re: topamax, posted by Toby on April 26, 1999, at 10:49:35
In my case (I weigh around 150) my doc started me at 50 mg and I have been on 100 mg for about 5 days. (I've noticed w/ p.m. dose that I have to stay awake for a good hour before going to bed because I reach a dream state before I'm actually sleeping and it freaks me out.) I'll be taking the Eskalith down a notch(450 mg) this week. I'll try to keep you posted next month on how I'm doing.
***another note--in the a.m.-- very groggy--may or may not be indicative of the topamax.
> What kinds of doses are working for you ladies? I've seen everything from 100 mg per day to 600 mg per day in the studies, but the studies also indicate that the higher doses make people cognitively dull. I have only one patient on it now (at 100 mg) and she's still got a little bit in the way of hypomania so we're slowly going to go up to 150 mg. She's very bright and in graduate school so I'm being cautious because I don't want to dull her intellect or creativeness, but at the same time when she's manic she doesn't get a whole lot of useful activities done either. I'm hoping we can find a happy medium with the Topamax.
Posted by Nancy on April 26, 1999, at 18:51:16
In reply to Re: topamax, posted by Toby on April 26, 1999, at 10:49:35
I was taking 100 mgs(and still on my way up in dosage) of Topomax. But, my pdoc has just stopped prescribing Topomax completely, because of a medical conference that he recently attended. So, I'm on Seroquel for the long run, I guess. :) Take care....N
> What kinds of doses are working for you ladies? I've seen everything from 100 mg per day to 600 mg per day in the studies, but the studies also indicate that the higher doses make people cognitively dull. I have only one patient on it now (at 100 mg) and she's still got a little bit in the way of hypomania so we're slowly going to go up to 150 mg. She's very bright and in graduate school so I'm being cautious because I don't want to dull her intellect or creativeness, but at the same time when she's manic she doesn't get a whole lot of useful activities done either. I'm hoping we can find a happy medium with the Topamax.
Posted by v on April 28, 1999, at 5:40:23
In reply to Re: topamax, posted by Nancy on April 26, 1999, at 18:51:16
what reason did he give for pulling the topomax?
i've been considering topomax along in addition to my effexor - last month the "new doc" wanted me to take zyprexa and/or risperdol (for sleep and his perception of my "agitated" mind which i don't agree with) but i refused because of weight gain issue other concerns... i'm not sure about this doc anyway as he didn't seem to hear a word i said re:meds - prescribing zyprexa AFTER i told him about my concerns of weight gain and that i'm a cyclist (prolonged heat/sun exposure being a no-no on this drug)
after reading toby's post now i'm worried about dullness!!! i struggle with thinking i'm an idiot and/or untalented enough w/o something actually rendering me so... would a very low dose be worth trying? i'm currently taking 150mg effexor XR in the morning and xanax occasionally (couple of times a week at most). i could probably benefit from a higher dose of effexor but would rather struggle at 150 and keep the side effects down
i'm seeing him friday... may try to find someone else after that
BTW, i'm also dissociative - somewhere along the continuum - as i've heard it put: "not clearly multipple but definitely not singleton"
thanks,
v> I was taking 100 mgs(and still on my way up in dosage) of Topomax. But, my pdoc has just stopped prescribing Topomax completely, because of a medical conference that he recently attended. So, I'm on Seroquel for the long run, I guess. :) Take care....N
>
>
> > What kinds of doses are working for you ladies? I've seen everything from 100 mg per day to 600 mg per day in the studies, but the studies also indicate that the higher doses make people cognitively dull. I have only one patient on it now (at 100 mg) and she's still got a little bit in the way of hypomania so we're slowly going to go up to 150 mg. She's very bright and in graduate school so I'm being cautious because I don't want to dull her intellect or creativeness, but at the same time when she's manic she doesn't get a whole lot of useful activities done either. I'm hoping we can find a happy medium with the Topamax.
Posted by Nancy on April 28, 1999, at 13:36:37
In reply to Re:topamax & dullness????, posted by v on April 28, 1999, at 5:40:23
Thanks for asking, v. It was a question that I'd put to him, but our appt was over and he was in a rush to get to the next client. I'll ask him this same question next week at my next appt. I'll let you know what his reasons were for refusing to prescribe topomax to anyone, anymore.
He's a psychopharmacologist who does alot of clinical research. During our last appt, he asked me to work for him as a research associate, publishing clinical research in major medical journals. We spent a great deal of time discussing this topic. Although, I have an honors degree in chemistry, a background of research associate experience in areas from organic and metallic chemistry to neurochemistry, and did some time in graduate school researching fetal tissue transplantation in the treatment of Parkinsonian, the last three years of my life I was struggling with treatment resistive bipolar-1 hell.
I feel lost and incompetent. I haven't regained full capacity, yet. I'm not sure what to expect over the next few months. I don't know when I'll be fully functional, again. I feel like these last few years were a tragic waste of time and ability.
My pdoc isn't worried, however. He's confident that I will, once again, be a shining star. He isn't going to rush me back into research. But, he's certain that I'll be capable very soon. I'm beginning to believe it, just a little bit, myself.
Nancy
> what reason did he give for pulling the topomax?
>
> i've been considering topomax along in addition to my effexor - last month the "new doc" wanted me to take zyprexa and/or risperdol (for sleep and his perception of my "agitated" mind which i don't agree with) but i refused because of weight gain issue other concerns... i'm not sure about this doc anyway as he didn't seem to hear a word i said re:meds - prescribing zyprexa AFTER i told him about my concerns of weight gain and that i'm a cyclist (prolonged heat/sun exposure being a no-no on this drug)
>
> after reading toby's post now i'm worried about dullness!!! i struggle with thinking i'm an idiot and/or untalented enough w/o something actually rendering me so... would a very low dose be worth trying? i'm currently taking 150mg effexor XR in the morning and xanax occasionally (couple of times a week at most). i could probably benefit from a higher dose of effexor but would rather struggle at 150 and keep the side effects down
>
> i'm seeing him friday... may try to find someone else after that
>
> BTW, i'm also dissociative - somewhere along the continuum - as i've heard it put: "not clearly multipple but definitely not singleton"
>
> thanks,
> v
>
> > I was taking 100 mgs(and still on my way up in dosage) of Topomax. But, my pdoc has just stopped prescribing Topomax completely, because of a medical conference that he recently attended. So, I'm on Seroquel for the long run, I guess. :) Take care....N
> >
> >
> > > What kinds of doses are working for you ladies? I've seen everything from 100 mg per day to 600 mg per day in the studies, but the studies also indicate that the higher doses make people cognitively dull. I have only one patient on it now (at 100 mg) and she's still got a little bit in the way of hypomania so we're slowly going to go up to 150 mg. She's very bright and in graduate school so I'm being cautious because I don't want to dull her intellect or creativeness, but at the same time when she's manic she doesn't get a whole lot of useful activities done either. I'm hoping we can find a happy medium with the Topamax.
Posted by Toby on April 29, 1999, at 14:38:40
In reply to Re:topamax & dullness????, posted by Nancy on April 28, 1999, at 13:36:37
To v.: My patient has not experienced any cognitive problems with the Topamax so far. When she was on Depakote, Lithium and neurontin she did have sedation and trouble concentrating (she wasn't on all three at once, just for clarification) so we're just being careful with the Topamax from the outset. I bumped her up to 200 mg early this week so we'll see how she does with that.
Posted by v on May 1, 1999, at 11:31:15
In reply to Re:topamax & dullness????, posted by Nancy on April 28, 1999, at 13:36:37
i have no doubt that you ARE a shining star... :)
how did you feel on the topamax? i just got them & am oh so scared (be careful what you ask for etc)... actually he thought it was a really good idea - but now i'm nervous about taking them - will start with 50mg at bedtime and hopefully not have to go higher than that to get some relief at night
i know what you mean about feeling that you've lost so much time in your life... too much of me is taken up with just surviving... it hurts when i think about what could have been... and like you, i'm trying to come up for air after the last couple of years of spinning and spiraling.
right now, i'm feeling sorry for myself... very unproductive... and very fat... i carry about 20 extra pounds of bodyfat that i can't get off despite cycling about 100 miles a week and weight training - can't eat clean for any length of time... sigh... a fat athlete just doesn't cut it... nor does the artist that doesn't create...
best,
v> Thanks for asking, v. It was a question that I'd put to him, but our appt was over and he was in a rush to get to the next client. I'll ask him this same question next week at my next appt. I'll let you know what his reasons were for refusing to prescribe topomax to anyone, anymore.
>
> He's a psychopharmacologist who does alot of clinical research. During our last appt, he asked me to work for him as a research associate, publishing clinical research in major medical journals. We spent a great deal of time discussing this topic. Although, I have an honors degree in chemistry, a background of research associate experience in areas from organic and metallic chemistry to neurochemistry, and did some time in graduate school researching fetal tissue transplantation in the treatment of Parkinsonian, the last three years of my life I was struggling with treatment resistive bipolar-1 hell.
>
> I feel lost and incompetent. I haven't regained full capacity, yet. I'm not sure what to expect over the next few months. I don't know when I'll be fully functional, again. I feel like these last few years were a tragic waste of time and ability.
>
> My pdoc isn't worried, however. He's confident that I will, once again, be a shining star. He isn't going to rush me back into research. But, he's certain that I'll be capable very soon. I'm beginning to believe it, just a little bit, myself.
>
> Nancy
>
>
> > what reason did he give for pulling the topomax?
> >
> > i've been considering topomax along in addition to my effexor - last month the "new doc" wanted me to take zyprexa and/or risperdol (for sleep and his perception of my "agitated" mind which i don't agree with) but i refused because of weight gain issue other concerns... i'm not sure about this doc anyway as he didn't seem to hear a word i said re:meds - prescribing zyprexa AFTER i told him about my concerns of weight gain and that i'm a cyclist (prolonged heat/sun exposure being a no-no on this drug)
> >
> > after reading toby's post now i'm worried about dullness!!! i struggle with thinking i'm an idiot and/or untalented enough w/o something actually rendering me so... would a very low dose be worth trying? i'm currently taking 150mg effexor XR in the morning and xanax occasionally (couple of times a week at most). i could probably benefit from a higher dose of effexor but would rather struggle at 150 and keep the side effects down
> >
> > i'm seeing him friday... may try to find someone else after that
> >
> > BTW, i'm also dissociative - somewhere along the continuum - as i've heard it put: "not clearly multipple but definitely not singleton"
> >
> > thanks,
> > v
> >
> > > I was taking 100 mgs(and still on my way up in dosage) of Topomax. But, my pdoc has just stopped prescribing Topomax completely, because of a medical conference that he recently attended. So, I'm on Seroquel for the long run, I guess. :) Take care....N
> > >
> > >
> > > > What kinds of doses are working for you ladies? I've seen everything from 100 mg per day to 600 mg per day in the studies, but the studies also indicate that the higher doses make people cognitively dull. I have only one patient on it now (at 100 mg) and she's still got a little bit in the way of hypomania so we're slowly going to go up to 150 mg. She's very bright and in graduate school so I'm being cautious because I don't want to dull her intellect or creativeness, but at the same time when she's manic she doesn't get a whole lot of useful activities done either. I'm hoping we can find a happy medium with the Topamax.
Posted by v on May 9, 1999, at 12:09:41
In reply to Re:topamax & dullness???? nancy, posted by v on May 1, 1999, at 11:31:15
nancy,
did you ever find out why your doctor took you off the topamax?
Posted by Nick on May 9, 1999, at 12:59:32
In reply to Re:topamax / nancy?, posted by v on May 9, 1999, at 12:09:41
Could someone tell what the generic name for topamax is? Nick
Posted by katie on May 9, 1999, at 18:53:31
In reply to Re:topamax - what is generic name, posted by Nick on May 9, 1999, at 12:59:32
> Could someone tell what the generic name for topamax is? Nick
I'm pretty sure it's toperimate (don't count on that being spelled right.)
Posted by Craig on May 10, 1999, at 1:47:36
In reply to Re:topamax - what is generic name, posted by Nick on May 9, 1999, at 12:59:32
> Could someone tell what the generic name for topamax is? Nick
Hi Nick, topiramate is the generic name of Topamax. I found this at www.rxlist.com
Posted by Toby on May 12, 1999, at 8:27:31
In reply to Re:topamax & dullness????, posted by Nancy on April 28, 1999, at 13:36:37
I don't want to be the big naysayer, but i would ask you to think a little about your doc's suggestion that you do research for him. Shrinks are just not supposed to have any kinds of dealings with their patients outside of the treatment relationship. It's an APA ehtical guideline. Psychiatrists have a fiduciary relationship with their patients, meaning a protective, nonexploitative relationship. The psychiatrist is not supposed to gain anything from the relationship other than a fee for services rendered and possibly an inner glow at seeing a patient do well. A social relationship, a work relationship, gifts, etc are just not supposed to develop because once a shrink has a vested interest in the patient other than professional, boundaries begin to blur and it becomes difficult for the doctor to see the patient's symptoms as symptoms, as problems to be remedied, and instead begins seeing the person as a friend or a business partner or employee or employer or whatever and once that point is reached, the doctor becomes useless as a therapist or even as a psychopharmacologist because the doctor is then treating the symptoms that bother him as they relate to his social interactions with the patient. This is why doctors are prohibited from treating family and friends. Of course, many doctors do treat family and friends and when this is discovered they often lose their license or at the very least have to go through alot of investigation and probation. And why? Because no matter how good the doctor is and no matter how wonderful their clinical judgement is, when it comes to family and friends, one cannot be properly objective and important symptoms will be missed just because they are familiar or minor symptoms will be overtreated because they annoy the doctor or because he can't say "no" now that he's been treating them for so long.
I've probably over-explained this, but I just want you to beware of the possible implications this could have on your treatment with him and/or your research work with him. What if you get well and start researching for him and then relapse and start doing poorly in your research? Is he in enough control of his feelings that he could see the symptoms returning early and not blame you for delayed publishing or faulty results and is he in enough control that this wouldn't bleed over into your psychiatric treatment? And if he had to let you go from the research job, could he still treat your illness effectively and could you still trust him with your treatment if you resented him terminating your job? And why did he spend so much time at your last appointment talking about what you could do for him rather than talking about your treatment? I realize you wanted to talk about it too because that is your interest, but for him, it is a slippery slope. Again, I want you to be able to return to your research and from your postings, I see your intelligence and am hopeful that this will be a reality for you, but I want you to be aware of the pitfalls of what your doctor proposed so you can make a good decision when the time comes.
Posted by Ellen Brodie on May 12, 1999, at 19:08:30
In reply to Re: topomax, posted by katie on April 20, 1999, at 22:38:44
> Nancy, I have been on Topmax for almost three weeks now. I have had a sugnificant decrease in appetite but I am not sure if that is the depression or the medication. It has made a sginificant diffence in helping to stbailizing my moods. I was starting with taking Klonopin at about 20mg a day now I am down to about half that anount. I am taking 200 mg of the topomax and have had bee please in the way it has helped my moods. Lots of side effects. Psycho motor slowing, cognitive dulling, definite taste changes, tingles in fingers. speech patterns have slowed almost to the point of stuttering, I am hoping over time these will lessen, My thoughts to these sides effects, I will take them to suicide attempts anyday. I have opted not to add a anti depressant to mt med care as i have done enougth research and I have not heard enough positve info that manic depressive patients do well on anti depressants. I woulld not go on depakote or litium because if weight gain. I am going to stick it out with the topomax and see how it goes. I can handle the side effects for now. I have learned to laugh at myself and am trying to have a good sense of humour. Positve self talk helps. Please let me now how your doing. Good Luck. Ellen
Posted by Chris A. on May 16, 1999, at 4:10:09
In reply to Re: topomax, posted by Ellen Brodie on May 12, 1999, at 19:08:30
To my friends who suffer from bipolar,
Posted by Aaron Friedman on May 27, 1999, at 20:49:47
In reply to Re: topamax, posted by Nancy on April 26, 1999, at 18:51:16
> I was taking 100 mgs(and still on my way up in dosage) of Topomax. But, my pdoc has just stopped prescribing Topomax completely, because of a medical conference that he recently attended. So, I'm on Seroquel for the long run, I guess. :) Take care....N
>
>
> > What kinds of doses are working for you ladies? I've seen everything from 100 mg per day to 600 mg per day in the studies, but the studies also indicate that the higher doses make people cognitively dull. I have only one patient on it now (at 100 mg) and she's still got a little bit in the way of hypomania so we're slowly going to go up to 150 mg. She's very bright and in graduate school so I'm being cautious because I don't want to dull her intellect or creativeness, but at the same time when she's manic she doesn't get a whole lot of useful activities done either. I'm hoping we can find a happy medium with the Topamax.I hav sone information on Topamax.. If the titration period is done at a very very slow rate (starting @ 25mg and inc @ 25mg per week the side effects are lessened
Posted by Ellen Brodie on May 28, 1999, at 5:34:48
In reply to Re: topamax, posted by Aaron Friedman on May 27, 1999, at 20:49:47
> I am now on 300mg a day of topomax. My doc has been uping the prescription at 50mg about every 10 days. As the time as gone on I have notice consideraberably less cognitive dulling. At first I was at the reading level or at least felt like I was at the reading level of a twelve year old. I am thirthy six. It has helped stabilized my moods and the side efects have decreased over time. I am also taking klonopin. I am bipolar and have a generalized anxiety disorder. I hope this helps. Good Luck. Ellen
Posted by Georgia F on May 29, 1999, at 23:27:30
In reply to Re: topamax, posted by Ellen Brodie on May 28, 1999, at 5:34:48
> > I am now on 300mg a day of topomax. My doc has been uping the prescription at 50mg about every 10 days. As the time as gone on I have notice consideraberably less cognitive dulling. At first I was at the reading level or at least felt like I was at the reading level of a twelve year old. I am thirthy six. It has helped stabilized my moods and the side efects have decreased over time. I am also taking klonopin. I am bipolar and have a generalized anxiety disorder. I hope this helps. Good Luck. Ellen
i am new to the whole ballgame of bipolar plus all of the medications involved...in the last year and and a half...i have been on a roller coaster of pills and doctors and side effects. I seem to not know what is wrong with me. The only thing they all agree on is ...i am bipolar..hard thing to find out at the late age...i was just kooky until now....i have been on lithium until three weeks ago among other things...and talk about extra weight...want some? 75 lbs in 14 months and now this incredible edema...i can barely walk...and i have 4 doctors telling me 4 different things...HELP!
Posted by Ellen Brodie on May 30, 1999, at 7:10:46
In reply to Re: topamax, posted by Aaron Friedman on May 27, 1999, at 20:49:47
> My doc took me up to 300mg of topomax. it was way to much in terms of the side effects. Actually the cognitive dulling has lessened alot but the anxiety was awful. I had her drop it back. I will proably have her go back to about 225. I seem to be able to stabilize my moods at that dosage. I notice though that my moods are the worse around my mentrual cycle. Any women out there concur with me!. Wish they that we could take pills just for that time of the month! HA!.
Posted by Georgia F. on May 30, 1999, at 18:15:51
In reply to Re: topamax, posted by Georgia F on May 29, 1999, at 23:27:30
disorder. I hope this helps. Good Luck. Ellen
>
> i am new to the whole ballgame of bipolar plus all of the medications involved...in the last year and and a half...i have been on a roller coaster of pills and doctors and side effects. I seem to not know what is wrong with me. The only thing they all agree on is ...i am bipolar..hard thing to find out at the late age...i was just kooky until now....i have been on lithium untilthree weeks ago among other things...and talk about extra weight...want some? 75 lbs in 14 months and now this incredible edema...i can barely walk...and i have 4 doctors telling me 4 different things...HELP!
yesterday i tried posting here...the 75 lbs woman....by the way my name is Georgia...duh..see there is also increased fat in head...lol...i just began the topamax two weeks ago along with serzone and resperdal...any advice?
thanks.....since i am dense...may be easier to emaild me...georgia
Posted by Ellen Brodie on May 30, 1999, at 18:56:01
In reply to Re: topamax, posted by Georgia F. on May 30, 1999, at 18:15:51
>i don't want to start handing out advice that I am not qualified to give but it sounds to be like you don't have much confidence on your doctors or your diagnosis. Find competent medical care. I have been through many doctors and have only in the past year gotten good treatment, but it was through alot of pain and effort that I got it. I was hospitalized once. Do your own research, read if you can and educate yourself as much as you can. If you need to e-mail me or want to chat more my e-mail is bodywizard@aol.com. Good Luck! trust me! You don'r need to suffer! Ellen
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> yesterday i tried posting here...the 75 lbs woman....by the way my name is Georgia...duh..see there is also increased fat in head...lol...i just began the topamax two weeks ago along with serzone and resperdal...any advice?
> thanks.....since i am dense...may be easier to emaild me...georgia
Posted by mj on May 10, 2000, at 15:09:33
In reply to Re: topamax, posted by Ellen Brodie on May 30, 1999, at 18:56:01
Has anyone LOST any weight with this topomax. I have gained 75lbs on lithium and zyprexa with dieting and exercising with a personal trainer. If anyone's had any luck with losing the weight please let me know how. Thanks
Posted by Brenda on May 12, 2000, at 13:30:21
In reply to Re: topamax, posted by mj on May 10, 2000, at 15:09:33
> Has anyone LOST any weight with this topomax. I have gained 75lbs on lithium and zyprexa with dieting and exercising with a personal trainer. If anyone's had any luck with losing the weight please let me know how. Thanks
Mj - I was on Topamax 100 mg. for about two months. I did experience loss of appetite. I was also on Wellbrutrin at the time and had absolutely no desire for food. It was actually a problem, as I have low blood sugar and would get hypoglycemic.
Good luck, Brenda
Posted by CH on May 31, 2000, at 13:34:46
In reply to Re: topamax, posted by Ellen Brodie on May 30, 1999, at 18:56:01
I'm currently taking Topamax and does curb your appetite. I've lost a few pounds.
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